Prognostic value of tumour budding in stomach cancers

2021 ◽  
Author(s):  
Sirin Kucuk
Keyword(s):  
Prognostic Value ◽  
Tumour Budding

scholarly journals The prognostic value of tumour stroma ratio and tumour budding in stage II colon cancer. A nationwide population-based study

2018 ◽  
Vol 33 (8) ◽  
pp. 1115-1124 ◽  
Author(s):  
Ann Christina Eriksen ◽  
Flemming B. Sørensen ◽  
Jan Lindebjerg ◽  
Henrik Hager ◽  
René dePont Christensen ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Prognostic Value ◽  
Population Based ◽  
Stage Ii ◽  
Tumour Stroma ◽  
Population Based Study ◽  
Stage Ii Colon Cancer ◽  
Tumour Budding

Prognostic value of tumour budding in oesophageal cancer: a meta-analysis

2015 ◽  
Vol 68 (2) ◽  
pp. 173-182 ◽  
Author(s):  
Alhadi Almangush ◽  
Markku Karhunen ◽  
Sampsa Hautaniemi ◽  
Tuula Salo ◽  
Ilmo Leivo
Keyword(s):  
Oesophageal Cancer ◽  
Prognostic Value ◽  
Meta Analysis ◽  
Tumour Budding

scholarly journals Tumour budding detected by laminin-5 γ2-chain immunohistochemistry is of prognostic value in epidermoid anal cancer

2005 ◽  
Vol 16 (6) ◽  
pp. 893-898 ◽  
Author(s):  
P.J. Nilsson ◽  
C. Rubio ◽  
C. Lenander ◽  
G. Auer ◽  
B. Glimelius
Keyword(s):  
Anal Cancer ◽  
Prognostic Value ◽  
Laminin 5 ◽  
Tumour Budding

scholarly journals Tumour-stroma ratio outperforms tumour budding as biomarker in colon cancer: a cohort study

2021 ◽  
Author(s):  
Marloes A. Smit ◽  
Gabi W. van Pelt ◽  
Valeska Terpstra ◽  
Hein Putter ◽  
Rob A. E. M. Tollenaar ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Survival Analysis ◽  
Prognostic Value ◽  
Tnm Classification ◽  
Disease Free Survival ◽  
Tumour Stroma ◽  
Intraobserver Agreement ◽  
Free Survival ◽  
Disease Free ◽  
Tumour Budding

AbstractThe tumour-stroma ratio (TSR) and tumour budding (TB) are two high-risk factors with potential to be implemented in the next TNM classification. The aim of the current study was to evaluate the practical application of the two biomarkers based on reproducibility, independency and prognostic value. Patients diagnosed with stage II or III colon cancer who underwent surgery between 2005 and 2016 were included. Both TSR and TB were scored on haematoxylin and eosin-stained tissue sections. The TSR, based on the relative amount of stroma, was scored in increments of 10%. TB was scored following the consensus guidelines; a bud was defined as ≤ 4 tumour cells. For analysis, three categories were used. Cohen’s kappa was used for reproducibility. The prognostic value was determined with survival analysis. In total, 246 patients were included. The TSR distribution was N = 137 (56%) stroma-low and N = 109 (44%) stroma-high. The TB distribution was TB-low N = 194 (79%), TB-intermediate N = 35 (14%) and TB-high N = 17 (7%). The reproducibility of the TSR was good (interobserver agreement kappa = 0.83 and intraobserver agreement kappa = 0.82), whereas the inter- and intraobserver agreement for scoring TB was moderate (kappa 0.47 and 0.45, respectively). The survival analysis showed an independent prognostic value for disease-free survival for TSR (HR 1.57; 95% CI 1.01–2.44; p = 0.048) and for TB-high (HR 2.01; 95% CI 1.02–3.96; p = 0.043). Based on current results, we suggest the TSR is a more reliable parameter in daily practice due to better reproducibility and independent prognostic value for disease-free survival.

Prognostic value of p53 and Ki67 expression in gastric carcinoid tumors

2001 ◽  
Vol 120 (5) ◽  
pp. A298-A299
Author(s):  
A SAFATLERIBEIRO ◽  
U RIBEIRO ◽  
C KOBATA ◽  
C CORBETT ◽  
K IRIYA ◽  
...  
Keyword(s):  
Prognostic Value ◽  
Carcinoid Tumors ◽  
Gastric Carcinoid ◽  
Ki67 Expression

1089: Prognostic Value of Molecular Staging of Bladder Cancer with RT -PCR Assay for KRT20: Results at 5 Year-Follow-up

2007 ◽  
Vol 177 (4S) ◽  
pp. 360-360
Author(s):  
Ana Agud ◽  
Maria J. Ribal ◽  
Lourdes Mengual ◽  
Mercedes Marin-Aguilera ◽  
Laura Izquierdo ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
Prognostic Value ◽  
Rt Pcr ◽  
Pcr Assay ◽  
Molecular Staging
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