scholarly journals Assessment of the optic nerve, optic disc, and perineural area using shear‐wave elastography in patients with multiple sclerosis

2021 ◽  
Author(s):  
Suna Sahın Edız ◽  
Basak Atalay ◽  
Ilknur Aydin Canturk ◽  
Adnan Kabaalıoglu
Keyword(s):  
Multiple Sclerosis ◽  
Optic Nerve ◽  
Optic Disc ◽  
Shear Wave ◽  
Shear Wave Elastography

scholarly journals Assessment of the optic nerve, optic disc, and perineural area using shear-wave elastography in patients with multiple sclerosis

2021 ◽  
Author(s):  
Suna Sahin Ediz ◽  
Basak Atalay ◽  
Ilknur Aydın Canturk ◽  
Adnan Kabaalioglu
Keyword(s):  
Multiple Sclerosis ◽  
Optic Nerve ◽  
Optic Neuritis ◽  
Optic Disc ◽  
Shear Wave ◽  
Shear Wave Elastography ◽  
Control Group ◽  
Optic Nerves ◽  
Significant Difference ◽  
The Mean

Purpose: To observe and describe the stiffness changes of the optic nerve in the patients with multiple sclerosis (MS) with or without optic neuritis and healthy adults via shear wave elastography (SWE). Methods: Seventy optic nerves from thirty-five patients with MS and sixty optic nerves from thirty healthy subjects were included prospectively in the study. The optic nerve (ON), optic disc (OD), and perineural area were evaluated with SWE and optic nerve sheat diameter (ONSD) was measured by ultrasound. Results The mean age of patients was 39.68 ± 9.99 years. There was no statistically significant difference between the groups in terms of ONSD, SWE ON, SWE OD, and SWE perineural area levels (p> 0.05). In the MS group; No statistically significant difference was found between patients with and without optic neuritis for the mean age, gender distribution, duration of MS, types of MS, ONSD, SWE ON, SWE OD, SWE perineural area, and Expanded Disability Status Scale (EDSS) scores (p> 0.05). No statistically significant difference in terms of ONSD, SWE ON, SWE OD, and SWE perineural area between the MS patients with or without optic neuritis and the control group (p> 0.05). Conclusion: Shear wave elastography measurements of the optic nerve, optic disc, and perineural area do not contribute to the evaluation of optic neuritis in a patient with MS.

scholarly journals Evaluation of the optic nerve using strain and shear wave elastography in patients with multiple sclerosis and healthy subjects

2017 ◽  
Vol 19 (1) ◽  
pp. 39 ◽  
Author(s):  
Mikail İnal ◽  
Sinan Tan ◽  
Erhan M. Yumusak ◽  
Mehmet Hamdi Şahan ◽  
Murat Alpua ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Optic Nerve ◽  
Healthy Volunteers ◽  
Shear Wave ◽  
Healthy Subjects ◽  
Shear Wave Elastography ◽  
Optic Nerves ◽  
Type 3

Aims: Our aim was to evaluate the elasticity features of the optic nerve using strain (SE) and shear wave elastography (SWE) in multiple sclerosis (MS) patients in comparison with healthy subjects. Material and methods: One hundred and seven optic nerves from 54 MS patients and 118 optic nerves from 59 healthy subjects were examined prospectively by SE and SWE. Optic nerves were divided into three types in accordance to the elasticity designs, as follows: type 1 predominantly blue (hardest tissue); type 2 predominantly blue/green (hard tissue); and type 3 predominantly green (intermediate tissue). Quantitative measurements of optic nerve hardness with SWE were analyzed in kilopascals. Results: Elastographic images from healthy volunteers showed mostly type 3 optic nerves (61.9%); type 2 was also found (38.1%), but type 1 was not observed. Elastographic examination of MS patients showed mostly type 2 optic nerves (88%), while some type 1 (4.6%) and type 3 optic nerves (6.5%) were rarely observed. There was a statistically significant difference in terms of elasticity patterns between patients and healthy volunteers (p<0.001). Statistically significant differences were observed between patients and healthy volunteers in the analysis of SWE values (10.381±3.48 kPa and 33.87±11.64 p<0.001). The receiver operating characteristic curve analysis was perfect (0.993; 95% confidence interval [CI]=0.971–0.999), and a cut-off value of 18.3 kPa shear had very high sensitivity and specificity for the patient group. No significant differences were observed between patients with and without previous optic neuritis. Conclusion: SE and SWE examination findings concerning the optic nerve in MS patients demonstrated remarkable differences according to the healthy group.

scholarly journals Shear wave elastography in optic neuritis: diagnostic accuracy of the optic nerve and adjacent fat tissue values

2021 ◽  
Vol 21 (86) ◽  
pp. e194-e199
Author(s):  
Mustafa Devran Aybar ◽  
◽  
Onder Turna ◽  
Keyword(s):  
Optic Nerve ◽  
Diagnostic Accuracy ◽  
Optic Neuritis ◽  
Shear Wave ◽  
Shear Wave Elastography ◽  
Curve Analysis ◽  
Fat Tissue ◽  
Roc Curve Analysis ◽  
Optic Nerves ◽  
The Mean

Introduction: In this study, we attempt to determine the diagnostic performance of shear wave elastography of the optic nerve and adjacent fat tissue in patients with optic neuritis. Methods: The study included a patient group consisting of 72 eyes of 36 patients who were diagnosed with unilateral optic neuritis, and an age-matched control group of 36 eyes of 18 healthy subjects. The patient group consisted of 25 multiple sclerosis patients and 11 recurrent isolated optic neuritis patients. The mean shear wave elastography values of the optic nerves and intraorbital fat tissue adjacent optic nerves were recorded using m/s and kPa as units. ROC curve analysis was performed, and the diagnostic accuracy of shear wave elastography values was determined. Results: The mean shear wave elastography values of the optic nerves with neuritis (2.49 ± 0.41 m/s and 17.56 ± 4.42 kPa) were significantly higher than the values of the contralateral normal optic nerves (1.71 ± 0.32 m/s and 9.02 ± 2.34 kPa) (p = 0.006 and p = 0.004, respectively) in the optic neuritis group. The mean shear wave elastography values of intraorbital fat tissue adjacent optic nerves with neuritis (1.87 ± 0.32 m/s and 9.65 ± 1.12 kPa) were significantly higher than the values of the contralateral normal side (1.47 ± 0.27 m/s and 6.78 ± 1.14 kPa) (p = 0.025 and p = 0.022, respectively) in the optic neuritis group. ROC curve analysis showed a high diagnostic accuracy for determining optic neuritis with shear wave elastography values of the optic nerves (AUC 0.955 [95% CI, 0.933–0.978] in m/s and AUC 0.967 [95% CI, 0.940–0.985] in kPa). Conclusions: Shear wave elastography may be an important alternative diagnostic tool in the diagnosis of optic neuritis.

Evaluation of the Optic Nerve by Strain and Shear Wave Elastography in Patients With Migraine

2018 ◽  
Vol 38 (5) ◽  
pp. 1153-1161 ◽  
Author(s):  
Mehmet Hamdi Şahan ◽  
Adil Doğan ◽  
Mikail İnal ◽  
Murat Alpua ◽  
Neşe Asal
Keyword(s):  
Optic Nerve ◽  
Shear Wave ◽  
Shear Wave Elastography

Evaluation of Optic Nerve with Strain and Shear Wave Elastography in Patients with Behçet's Disease and Healthy Subjects

2017 ◽  
Vol 43 (7) ◽  
pp. 1348-1354 ◽  
Author(s):  
Mikail Inal ◽  
Sinan Tan ◽  
Serkan Demirkan ◽  
Veysel Burulday ◽  
Özgür Gündüz ◽  
...  
Keyword(s):  
Optic Nerve ◽  
Shear Wave ◽  
Behçet’S Disease ◽  
Healthy Subjects ◽  
Behcet’S Disease ◽  
Behçet's Disease ◽  
Shear Wave Elastography ◽  
Behcet's Disease

Biomechanical properties of optic nerve and retrobulbar structures with 2D and 3D shear wave elastography in patients affected by glaucoma

2020 ◽  
Vol 61 ◽  
pp. 106-114
Author(s):  
Manlio Guazzaroni ◽  
Donatella Ferrari ◽  
Feliciana Lamacchia ◽  
Fabio Salimei ◽  
Salvatore Marsico ◽  
...  
Keyword(s):  
Optic Nerve ◽  
Shear Wave ◽  
Shear Wave Elastography ◽  
Biomechanical Properties ◽  
2D And 3D

Evaluation of the optic nerve using strain and shear-wave elastography in pre-eclampsia

2019 ◽  
Vol 74 (10) ◽  
pp. 813.e1-813.e9 ◽  
Author(s):  
N. Asal ◽  
C.D. Sayan ◽  
N.B. Gökçınar ◽  
M.H. Şahan ◽  
A. Doğan ◽  
...  
Keyword(s):  
Optic Nerve ◽  
Shear Wave ◽  
Shear Wave Elastography

Shear wave elastography evaluation of brachial plexus in multiple sclerosis

2021 ◽  
pp. 028418512110028
Author(s):  
Enes Gürün ◽  
İsmail Akdulum ◽  
Melih Akyüz ◽  
Suna Özhan Oktar
Keyword(s):  
Multiple Sclerosis ◽  
Brachial Plexus ◽  
Shear Wave ◽  
Nerve Root ◽  
Shear Wave Elastography ◽  
Control Group ◽  
Control Groups ◽  
Nerve Roots ◽  
Peripheral Nerve Involvement ◽  
And Control

Background Multiple sclerosis (MS) is a chronic neuroinflammatory disease characterized by inflammation involving the peripheral nerves. Shear wave elastography (SWE) is potentially a method of choice for detecting peripheral nerve involvement. Purpose To compare the degree of thickening and nerve elasticity of brachial plexus (BP) nerve roots and evaluate the usefulness of sonoelastography in patients with clinically diagnosed MS without brachial plexopathy. Material and Methods Thirty-two patients with MS and 32 controls were included in the study. Bilateral C5, C6, and C7 mean nerve root diameters, and mean elasticity values in kiloPascal (kPa) were measured in the patient and control groups. The relationship between the age, height, and weight values and nerve diameter-elasticity values of the patient and control groups was compared. Results The elasticity values of the C5 and C6 nerve roots were increased, and the nerve root thickness was decreased in the MS group compared to that in the control ( P < 0.05). There was no difference between the C7 mean nerve root elasticity (kPa) and diameter measurements in the patient and control groups ( P > 0.05). Conclusion Our study showed an increase in the BP nerve root elasticity values (kPa) in patients with MS compared to that of the control group and a decrease in diameter values thought to be related to the possible chronic atrophic process. The results are consistent with the demyelinating process of the peripheral nervous system (PNS) due to MS.

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