scholarly journals Proposal for a clinical and an echocardiographic score for prediction of left atrial thrombosis in atrial fibrillation patients undergoing early electrical cardioversion

Author(s):  
Antonio Vincenti ◽  
Luca Porcu ◽  
Andrea Sonaglioni ◽  
Simonetta Genovesi
2019 ◽  
Vol 2019 ◽  
pp. 1-7
Author(s):  
Rasa Karaliute ◽  
Justina Jureviciute ◽  
Julija Jurgaityte ◽  
Giedre Stanaitiene ◽  
Vaida Mizariene ◽  
...  

Atrial fibrillation (AF) despite the absence of heart failure is related to increased levels of natriuretic peptides (NPs). NPs have not been widely investigated in relation to left atrium (LA) function after sinus rhythm (SR) restoration and duration of AF. The aim of the study was to determine the changes of NPs levels and to define their relation with LA phasic function after electrical cardioversion (ECV). Methods. The study included 48 persistent AF patients with restored SR after ECV. NT-proANP and NT-proBNP were measured for all patients before the ECV. LA phasic function (reservoir, conduit, and pump phases) was assessed using echocardiographic volumetric analysis within the first 24 hours after ECV. Patients were repeatedly tested after 1 month in case of SR maintenance. Results. After 1 month, SR was maintained in 26 (54%) patients. For those patients, NT-proBNP decreased significantly (p=0.0001), whereas NT-proANP tended to decrease (p=0.13). Following 1 month after SR restoration, LA indexed volume decreased (p=0.0001) and all phases of LA function improved (p=<0.01). Patients with AF duration < 3 months had lower NT-proANP compared to patients with AF duration from 6 to 12 months (p = 0.005). Higher NT-proANP concentration before ECV was associated with lower LA reservoir function during the first day after SR restoration (R=-0.456, p=0.005), whereas higher NT-proBNP concentration after 1 month in SR was significantly related to lower LA reservoir function (R=-0.429, p=0.047). Conclusions. LA indexed volume, all phases of LA function, and NT-proBNP levels improved significantly following 1 month of SR restoration. Preliminary results suggest that higher baseline NT-proANP levels and higher NT-proBNP for patients with maintained SR for 1 month are related to lower LA reservoir function. The longer duration of persistent AF is associated with higher NT-proANP concentration.


2016 ◽  
Vol 94 (6) ◽  
pp. 433-438
Author(s):  
Alevtina V. Grontkovskaya ◽  
N. N. Borovkov ◽  
N. V. Amineva

The article considers the influence of arterial hypertension on the frequency of intra-atrial thrombosis in patients with atrial fibrillation (AF) of non-valvular etiology. Materials and methods. 38 patients were examined (26 men and 12 women) aged 35 to 75 years with documented AF. Paroxysmal AF was diagnosed in 10 patients (26.32%). The persistent and permanent forms of arrhythmia were revealed in 14 cases (36.84%). Stage II-III hypertensive disease (HD) was diagnosed in 27 patients (71.1%). The transthoracic and transesophageal echocardiography was performed with the use of ultrasonic devices such as Aloka-SSD-4000 ProSound (Japan) and PhilipsIE 33 (USA). Results. The analysis of results of echocardiography (both transthoracic and transesophageal) made it possible to detect intra-atrial clots in 54,8% of the patients with AF of non-valvular etiology. Atrial cavity thrombosis was registered in 15 of the 22 cases (68,2%) among the patients with hypertension as a direct cause of AF or another concomitant pathology. Lower blood flow velocity from the left atrial appendage was registered in hypertensive patients compared to those without hypertension - 29.0 (4.2) and 35.4 respectively (8.1) mm/s (p = 0.038; Student's t-test). The reduction of the peak bloodflow velocity in the left atrial appendage was proportional to the increase of hypertension (R = -0,861; p <0,001; R - Spearman's coefficient). The frequency of intra-atrial thrombosis did not depend on the form of atrialfibrillation and duration of the arrhythmic anamnesis. Conclusion. Hypertension is an independent predictor of thromboembolic complications in atrial fibrillation of non-valvular etiology.


1991 ◽  
Vol 67 (1) ◽  
pp. 93-95 ◽  
Author(s):  
Isabelle C. Van Gelder ◽  
Harry J. Crijns ◽  
Wiek H. Van Gilst ◽  
Hans P.M. Hamer ◽  
Kong I. Lie

2013 ◽  
Vol 34 (suppl 1) ◽  
pp. P1103-P1103
Author(s):  
A. Zimmermann ◽  
M. Bossard ◽  
S. Aeschbacher ◽  
T. Schoen ◽  
G. Voellmin ◽  
...  

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