scholarly journals The relation between increased carotid intima‐media thickness with fibrin monomers in obese Children

2021 ◽  
Author(s):  
Esra Yazarlı ◽  
Rukiye Ünsal Saç ◽  
Betül Şimşek ◽  
Özlem Engiz ◽  
Yıldız Dallar Bilge ◽  
...  
Keyword(s):  
Intima Media Thickness ◽  
Carotid Intima Media Thickness ◽  
Obese Children ◽  
Media Thickness ◽  
Fibrin Monomers

scholarly journals The relation between increased carotid intima-media thickness with fibrin monomers in obese children

2021 ◽  
Author(s):  
Esra Yazarlı ◽  
Rukiye Saç ◽  
Betül Şimşek ◽  
Özlem Engiz ◽  
Bulent Alioglu ◽  
...  
Keyword(s):  
Childhood Obesity ◽  
Intima Media Thickness ◽  
Carotid Intima Media Thickness ◽  
Healthy Control Group ◽  
Control Group ◽  
Obese Children ◽  
Media Thickness ◽  
Healthy Control ◽  
Fibrin Monomers ◽  
D Dimer

Objective: This study aimed to investigate the association between carotid intima-media changes that play a part in the atherosclerotic process in childhood obesity and fibrin monomers as an important indicator of fibrin plaque. Methods: This is a cross-sectional study of obese children and non-obese healthy control subjects. Height, weight, body mass index, waist/hip ratio, systolic/diastolic blood pressures were recorded, in addition, biochemistry, hemogram, fibrin monomers and d-dimer were measured in both groups. Right and left common carotid intima-media thicknesses were measured by ultrasonography and mean carotid intima-media thickness was calculated. Results: Obese children (n=89, 46.1% girls, median age: 12.6±2.3 years) and healthy control group (n=40, 52.5% girls, median age: 13.2±2.2 years) were comparable in terms of gender, age and puberty stage. Mean carotid intima-media thickness was higher in obese children than the healthy control group (p=0.002). There was no difference between the two groups in terms of fibrin monomers and D-dimer levels. In obese children, there was a weak negative correlation between mean carotid intima-media thickness and fibrin monomers (p=0.030, r=-0.233). Conclusion: In obese children, mean carotid intima-media thickness was determined higher, as an early indicator of atherosclerosis. We want to emphasize that obese children are at risk for cardiovascular disease and should be evaluated in terms of atherosclerosis. This study investigates the relation between increased carotid intima-media thickness and fibrin monomers, in children, the first time in Literature. What’s already known about this topic? It is possible to reveal the early period of the atherosclerosis process by showing carotid intima medial thickness. Fibrin is a major component of many atherosclerotic plaques. What does this article add? Our study investigated the relationship between mean carotid intima-media thickness in childhood obesity and fibrin monomers. But no positive correlation was found between fibrin monomers and the carotid intima-media thickness.

scholarly journals Lean Body Mass May Explain Apparent Racial Differences in Carotid Intima-Media Thickness in Obese Children

2014 ◽  
Vol 27 (5) ◽  
pp. 561-567 ◽  
Author(s):  
Shahryar M. Chowdhury ◽  
Melissa H. Henshaw ◽  
Brad Friedman ◽  
J. Philip Saul ◽  
Girish S. Shirali ◽  
...  
Keyword(s):  
Racial Differences ◽  
Lean Body Mass ◽  
Body Mass ◽  
Intima Media Thickness ◽  
Carotid Intima Media Thickness ◽  
Obese Children ◽  
Media Thickness

scholarly journals Serum TSH level in obese children and its correlations with atherogenic lipid indicators and carotid intima media thickness

2018 ◽  
Vol 18 (75) ◽  
pp. 296-301
Author(s):  
Małgorzata Rumińska ◽  
◽  
Ewelina Witkowska-Sędek ◽  
Anna Majcher ◽  
Michał Brzewski ◽  
...  
Keyword(s):  
Intima Media Thickness ◽  
Carotid Intima Media Thickness ◽  
Obese Children ◽  
Media Thickness ◽  
Serum Tsh ◽  
Atherogenic Lipid

scholarly journals Carotid intima-media thickness and cardiovascular risk factors in childhood and adolescent obesity

2018 ◽  
Vol 5 (11) ◽  
pp. 4643
Author(s):  
Aml A. Mahfouz ◽  
Mohamed N. Massoud ◽  
Omneya M. Omar ◽  
Ahmed M. Abou–Gabal
Keyword(s):  
Blood Pressure ◽  
Cardiovascular Risk ◽  
Intima Media Thickness ◽  
Carotid Intima Media Thickness ◽  
The Body ◽  
Anthropometric Measurement ◽  
Model Assessment ◽  
Fasting Insulin ◽  
Obese Children ◽  
Media Thickness

Background: Childhood obesity is a significant health problem that has reached epidemic proportions around the world and it is a risk factor for atherosclerosis. The study aimed to investigate carotid intima-media thickness (CIMT) in obese children and evaluate the relationship of CIMT to various cardiovascular risk factors.Methods: This was achieved through including 40 obese children aged 5-16 years who were referred to Alexandria University Children's Hospital (AUCH) and 20 non-obese age and sex-matched children as the control group. All obese children in this study were subjected to thorough history taking, thorough clinical examination stressing on anthropometric measurement, blood pressure measurement and laboratory investigations including lipid profile, liver function tests, fasting glucose and fasting insulin and ultrasonographic study for the liver and carotid intima-media thickness measurement.Results: compared to the control, the obese children demonstrated a significantly thicker carotid intima-media (p<0.001). Univariate correlation analysis revealed that CIMT was significantly correlated with the body mass index (BMI), waist circumference measurement, diastolic blood pressure (DBP), high-density lipoprotein cholesterol (HDLC), fasting insulin, homeostasis model assessment- insulin resistance (HOMA-IR), quantitative insulin-sensitivity check index (QUICKI) and fatty liver. In multiple linear regression analysis, CIMT correlated significantly with DBP in the obese group.Conclusions: Atherosclerosis begins in obese children and adolescents and CIMT measurement is a noninvasive, feasible, reliable and inexpensive method to detect subclinical atherosclerosis. 

scholarly journals Evaluation oF Epicardial Fat and Carotid Intima-Media Thickness in Obese Children

2016 ◽  
Vol 26 (1) ◽  
Author(s):  
Hatem Hamed Elshorbagy ◽  
ElSaeed R. Fouda ◽  
Naglaa M. Kamal ◽  
Mohammed M. Bassiouny ◽  
Waleed M. Fathi
Keyword(s):  
Intima Media Thickness ◽  
Carotid Intima Media Thickness ◽  
Epicardial Fat ◽  
Obese Children ◽  
Media Thickness
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