Vitamin D level in a sample of Egyptian females of childbearing age attending a family medicine center

Author(s):  
Maivel Emile Soby Gerges ◽  
Ghada Essam Aldin Amin ◽  
Fady Andraous ◽  
Diaa Marzouk Abdel Hamid ◽  
Mohamed Farouk Allam
2010 ◽  
Vol 202 (5) ◽  
pp. e1-e3 ◽  
Author(s):  
George A. Macones ◽  
Jennifer Allsworth ◽  
Lorie Harper ◽  
Katherine Goetzinger

2010 ◽  
Vol 202 (5) ◽  
pp. 436.e1-436.e8 ◽  
Author(s):  
Adit A. Ginde ◽  
Ashley F. Sullivan ◽  
Jonathan M. Mansbach ◽  
Carlos A. Camargo

2018 ◽  
Vol 52 (9) ◽  
pp. 876-883 ◽  
Author(s):  
Brandi L. Bowers ◽  
Amy M. Drew ◽  
Christian Verry

Background: The vast majority of women at high risk for osteoporotic fractures are not treated, despite known significant clinical and economic consequences of this prevalent condition. To date, this is the first study of this size and duration to examine the role of pharmacists in management of osteoporosis in a family medicine clinic. Objective: To compare the initiation or continuation of prescription antifracture therapy in high-risk patients with collaborative pharmacist-physician to physician-only management; secondarily, to evaluate recommendation rates for antifracture therapy and calcium and vitamin D. Methods: This retrospective cohort analysis included women older than 65 years with a dual-energy X-ray absorptiometry (DXA) scan ordered by a family medicine physician. High risk was defined as T-scores ≤−2.5 at the lumbar spine, femoral neck, or 33% radius, or a FRAX 10-year fracture risk score ≥20% for major osteoporosis-related or ≥3% for hip fractures. Results: There were 466 (311 high-risk) pharmacist-physician and 549 (237 high-risk) physician-managed DXAs included. For high-risk DXAs, collaborative management resulted in increased rates of receiving antifracture therapy prescriptions over physician-only management (66% vs 34%, P < 0.001), advisement for antifracture therapy (87% vs 32%, P < 0.001), and calcium and vitamin D (97% vs 45%, P < 0.001). Collaborative management also improved calcium and vitamin D advisement among all DXAs (96% vs 46%, P < 0.01). There was no difference in adverse events documented in the pharmacist-physician compared with physician-only management (7.2% vs 3.7%, P = 0.32). Conclusion and Relevance: Pharmacist-physician collaboration is associated with higher treatment rates of osteoporosis. This study supports the pharmacist-physician partnership as one method of improving osteoporosis management.


1998 ◽  
Vol 30 (4) ◽  
pp. 431-437 ◽  
Author(s):  
ADEKUNLE DAWODU ◽  
GAMIL ABSOOD ◽  
MAHENDRA PATEL ◽  
MUKESH AGARWAL ◽  
MUTAIRU EZIMOKHAI ◽  
...  

Low serum 25-OHD in female Arab subjects, which may predispose their infants to hypocalcaemia, has been suggested to be due to inadequate sunshine exposure, but may include other sociobiological factors. The effects of duration of sunshine exposure - weighted against the magnitude of clothing (UV exposure) and other sociobiological variables such as age, education and living accommodation - on serum 25-OHD and mineral status of 33 UAE national women of childbearing age were compared with those of 25 non-Gulf Arabs and seventeen Europeans. Serum concentrations of calcium, phosphorus, alkaline phosphatase and intact parathyroid hormone among the groups were not significantly different. The serum concentration of 25-OHD in UAE nationals was 8·6 ng/ml (4·5–17·4), mean±1 SD, and in non-Gulf Arabs 12·6 ng/ml (6·0-26·4); both these values were significantly lower (p=<50·0001) than the 64·3 ng/ml (49-84·3) found in Europeans. Compared with Europeans, the UAE and non-Gulf Arabs in this study were younger, had fewer years of education and had significantly lower clothing and UV scores (p<0·0001). Furthermore, there was a positive correlation (r=0·59425) between serum 25-OHD and UV score, but not with length of exposure. After adjusting for other confounding variables, nationality, clothing and UV scores remained major determinants of serum 25-OHD (p<0·0001). Therefore, limited skin exposure to sunlight appears to be an important determinant of vitamin D status in our subjects. Strategies to increase vitamin D stores should include vitamin D supplementation or advice on effective sunlight exposure.


2008 ◽  
Vol 100 (2) ◽  
pp. 269-272 ◽  
Author(s):  
Rosa M. Ortega ◽  
Aránzazu Aparicio ◽  
Elena Rodríguez-Rodríguez ◽  
Laura M. Bermejo ◽  
José M. Perea ◽  
...  

The loss of weight was analysed in a group of sixty overweight/obese women of childbearing age (20–35 years) according to their initial vitamin D status. Subjects were randomly assigned to one of two slightly hypocaloric diets: Diet V, in which the consumption of vegetables was increased, or Diet C, in which the relative consumption of cereals (especially breakfast cereals) was increased. Dietetic, anthropometric and biochemical data were collected at the start of the study and again at 2 weeks after dividing the women into groups depending on their having an initial serum 25-hydroxyvitamin D (25(OH)D) concentration of < 50 nmol/l (LD) or ≥ 50 nmol/l (HD). Dietary intervention led to a reduction in energy intake, body weight and BMI in all groups. The HD women showed greater body fat losses during the study than the LD women (1·7 (sd 1·8) kg compared to 0·5 (sd 0·8) kg). A better vitamin D status therefore aided the loss of body fat over the experimental period (OR 0·462; CI 0·271, 0·785; P < 0·001). However, when the dietary groups were analysed separately, this effect was only seen in the C subjects (OR 0·300; CI 0·121, 0·748; P < 0·001). The present results suggest that women with a better vitamin D status respond more positively to hypocaloric diets and lose more body fat; this was especially clear among the C subjects who had a greater vitamin D supply during the experimental period.


Sign in / Sign up

Export Citation Format

Share Document