scholarly journals A prospective clinical study of regenerative endodontic treatment of traumatized immature teeth with necrotic pulps using bi-antibiotic paste

2017 ◽  
Vol 51 ◽  
pp. e204-e215 ◽  
Author(s):  
H. Nazzal ◽  
K. Kenny ◽  
A. Altimimi ◽  
J. Kang ◽  
M. S. Duggal
Keyword(s):  
Clinical Study ◽  
Endodontic Treatment ◽  
Prospective Clinical Study ◽  
Immature Teeth ◽  
Regenerative Endodontic Treatment

Regenerative Endodontic Treatment versus Apical Plug in Immature Teeth: Three-Year Follow-Up

2016 ◽  
Vol 40 (5) ◽  
pp. 356-360 ◽  
Author(s):  
Saeed Asgary ◽  
Mahta Fazlyab ◽  
Ali Nosrat
Keyword(s):  
Endodontic Treatment ◽  
Treatment Protocols ◽  
Anterior Maxilla ◽  
Periapical Lesions ◽  
Cem Cement ◽  
Immature Teeth ◽  
Tooth Discoloration ◽  
History Of ◽  
The Right ◽  
Regenerative Endodontic Treatment

This report compares and evaluates the treatment outcomes of regenerative endodontic treatment and apical plug as two accepted treatment protocols in a pair of necrotic immature maxillary central incisors of a 12-year old female. The patient was referred complaining of a dull pain and swelling in her upper lip area. She had a history of trauma to the anterior maxilla two years earlier. Both teeth were clinically diagnosed with pulp necrosis and periapical radiographs revealed that separate periapical radiolucent lesions surrounded the immature apices of both teeth. The left and right incisors were treated with apical plug and regenerative endodontic treatment, respectively, using calcium-enriched mixture (CEM) cement. The patient was followed-up for three years. During this period, both teeth were clinically asymptomatic and showed complete radiographic healing of the periapical lesions. The right central incisor showed root development. No tooth discoloration was evident. Apexification by apical plug placement and pulp regeneration are both reliable treatments for immature non-vital teeth. In order to choose the right treatment the advantages of either technique should be weighed against its drawbacks. CEM cement can be successfully applied for both purposes. This biomaterial causes less discoloration of the tooth.

scholarly journals 12-Year Follow-Up of Regenerative Endodontic Treatment of Immature Permanent Upper Incisors with Acute Abscess

2020 ◽  
Vol 31 (6) ◽  
pp. 680-684
Author(s):  
Claudio Maniglia-Ferreira ◽  
Eduardo Diogo Gurgel Filho ◽  
Fabio de Almeida Gomes ◽  
Sthefanny Amaral Reis ◽  
Fernanda Geraldo Pappen
Keyword(s):  
Clinical Success ◽  
Glass Ionomer Cement ◽  
Mineral Trioxide Aggregate ◽  
Endodontic Treatment ◽  
Treatment Access ◽  
Root Canals ◽  
Immature Teeth ◽  
The Right ◽  
Regenerative Endodontic Treatment

Abstract This case report discusses the endodontic treatment of a 7-year-old girl who suffered trauma (intrusion) to the immature upper central incisors secondary to a fall from a bicycle. Thirty days after the accident the patient was brought by her mother for clinical and radiographic assessment with a chief complaint of swelling and tenderness to percussion and palpation. Acute apical abscess associated with immature teeth were diagnosed. A decision was made to perform regenerative endodontic treatment. Access cavities were made and the root canals were disinfected by irrigation with 2.5% sodium hypochlorite. Final irrigation was performed with 17% EDTA. Due to pain and presence of secretions, 2% chlorhexidine gel was applied as an intracanal medicament. Seven days later, at the second visit, the root canals were once again disinfected and the canals of the right and left permanent upper central incisors were filled with double antibiotic paste (metronidazole/ciprofloxacin) and calcium hydroxide paste, respectively. Zinc oxide was mixed in both pastes. At the third visit, after 21 more days, the pastes were removed and the periapical areas were stimulated with a #80 K-file to encourage clot formation within the pulp cavities. A mineral trioxide aggregate (MTA) paste cervical plug was placed and the teeth were restored with glass ionomer cement. Radiographs and CBCT scans demonstrated complete root formations. The patient has been followed for 12 years, with evidence of clinical success throughout.

scholarly journals Prognostic validity of the Periapical and Endodontic Status Scale for the radiographically assessed 2-year treatment outcomes in teeth with apical periodontitis: a prospective clinical study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Jelena Gudac ◽  
Kristina Hellén-Halme ◽  
Vita Machiulskiene
Keyword(s):  
Treatment Outcome ◽  
Clinical Study ◽  
High Risk ◽  
Treatment Outcomes ◽  
Risk Group ◽  
High Risk Group ◽  
Endodontic Treatment ◽  
Prospective Clinical Study ◽  
Root Canals ◽  
Treatment Risk

Abstract Background Endodontic treatment planning and treatment success evaluation are largely based on radiographic assessment of anatomical and treatment-related parameters of teeth with apical periodontitis (AP). This prospective clinical study aimed to assess radiographically the 2-year endodontic treatment outcomes for teeth with AP, and to evaluate prognostic validity of Periapical and Endodontic Status Scale (PESS). Methods A total of 128 patients, representing 176 teeth with AP were examined by cone-beam computed tomography at baseline and at 24 months after endodontic treatment. Treatment outcome was evaluated using estimates of periapical radiolucency and the relationship between anatomical structures and location. The strength of the associations between these and treatment-related parameters was tested by logistic regression analysis. PESS sensitivity and specificity were calculated for every treatment risk group (low, moderate, high) of teeth. Results One hundred and fifty-seven teeth, representing 350 root canals had a positive treatment outcome, while 19 teeth, representing 53 root canals had a negative treatment outcome at 24 months. The probability of negative outcome was 25 times higher in the moderate/high-risk group than in the mild-risk group of teeth (OR = 25.1; 95%CI [12.2–51.5]). Pre-treatment complications and retreatment cases with radiolucency were associated with negative outcomes (OR = 35.9; 95%CI [12.6–102.4]; OR = 26.437; 95%CI [10.9–64.1], respectively). PESS sensitivity and specificity was over 80% in all risk groups except for high risk group, due to very low number of cases. Conclusions Endodontic treatment outcome depends on the severity of periapical changes. The presence of complications and retreatment cases with periapical lesions are associated with negative treatment outcome. The PESS is a valid instrument to predict outcome of teeth with low-moderate treatment risk of AP.

scholarly journals Unpredictable Outcomes of a Regenerative Endodontic Treatment

2021 ◽  
Vol 2021 ◽  
pp. 1-6
Author(s):  
Zahra Mohammadi ◽  
Hadi Assadian ◽  
Behnam Bolhari ◽  
Mohammadreza Sharifian ◽  
Mehrfam Khoshkhounejad ◽  
...  
Keyword(s):  
Bacterial Contamination ◽  
Root Apex ◽  
Sinus Tract ◽  
Endodontic Treatment ◽  
Central Incisor ◽  
Immature Teeth ◽  
Valuable Treatment ◽  
Radiolucent Lesion ◽  
Regenerative Endodontic Treatment

Regenerative endodontic treatment (RET) is a valuable treatment for necrotic immature teeth with many advantages such as increasing root length and thickness of root wall. The success of RETs is based on healthy stem cells, suitable scaffolds, and growth factors and takes place when bacterial contamination is well controlled. The aim of this article is to address controversy in a case with multiple success criteria. This paper reports a 9-year-old boy with a complicated crown fracture of the maxillary left central incisor about three years prior to referral with a diagnosis of intrusive luxation with spontaneous reeruption. The tooth had an underdeveloped root and a well-defined periapical radiolucent lesion around the root apex. RET was considered according to the stage of root development. Upon the three-week recall session, the clinical examination indicated that the patient was asymptomatic in the affected site. However, the patient returned two weeks later with a sinus tract pertaining to the apex of tooth #9. Therefore, debridement of the root canal space was repeated and the RET redone. On the second trial, the patient was symptom-free, but no more evidence of root maturation was observed on 18-month follow-up. The tooth was asymptomatic (without swelling, drainage, and pain) during this time, and esthetics was provided for the patient.

scholarly journals Different Approaches to the Regeneration of Dental Tissues in Regenerative Endodontics

2021 ◽  
Vol 11 (4) ◽  
pp. 1699
Author(s):  
Anna M. Krupińska ◽  
Katarzyna Skośkiewicz-Malinowska ◽  
Tomasz Staniowski
Keyword(s):  
Case Reports ◽  
Endodontic Treatment ◽  
Cochrane Library ◽  
Root Canal Therapy ◽  
Dental Tissues ◽  
Regenerative Endodontics ◽  
Manual Search ◽  
Immature Teeth ◽  
Pulp Revascularization ◽  
Regenerative Endodontic Treatment

(1) Background: The regenerative procedure has established a new approach to root canal therapy, to preserve the vital pulp of the tooth. This present review aimed to describe and sum up the different approaches to regenerative endodontic treatment conducted in the last 10 years; (2) Methods: A literature search was performed in the PubMed and Cochrane Library electronic databases, supplemented by a manual search. The search strategy included the following terms: “regenerative endodontic protocol”, “regenerative endodontic treatment”, and “regenerative endodontics” combined with “pulp revascularization”. Only studies on humans, published in the last 10 years and written in English were included; (3) Results: Three hundred and eighty-six potentially significant articles were identified. After exclusion of duplicates, and meticulous analysis, 36 case reports were selected; (4) Conclusions: The pulp revascularization procedure may bring a favorable outcome, however, the prognosis of regenerative endodontics (RET) is unpredictable. Permanent immature teeth showed greater potential for positive outcomes after the regenerative procedure. Further controlled clinical studies are required to fully understand the process of the dentin–pulp complex regeneration, and the predictability of the procedure.

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