Ion release and mechanical properties of calcium silicate and calcium hydroxide materials used for pulp capping

2014 ◽  
Vol 48 (1) ◽  
pp. 89-94 ◽  
Author(s):  
L. C. Natale ◽  
M. C. Rodrigues ◽  
T. A. Xavier ◽  
A. Simões ◽  
D. N. de Souza ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Calcium Hydroxide ◽  
Calcium Silicate ◽  
Ion Release ◽  
Pulp Capping ◽  
Materials Used

scholarly journals Induction of reparative dentin by calcium silicate-based material as direct pulp capping agent

2019 ◽  
Vol 12 (4) ◽  
pp. 182-186
Author(s):  
Mozammal Hossain ◽  
Mahmood Sajedeen ◽  
Yukio Nakamura
Keyword(s):  
Calcium Hydroxide ◽  
Calcium Silicate ◽  
Normal Function ◽  
Direct Pulp Capping ◽  
Pulp Tissue ◽  
Pulp Capping ◽  
Exposure Site ◽  
Reparative Dentin ◽  
Dentin Formation ◽  
Reparative Dentin Formation

This study was performed to examine whether calcium silicate could induce reparative dentin formation without eliciting any adverse effect in direct pulp capping of premolar teeth. Twenty participants who need extraction of their 4 healthy permanent premolar teeth for orthodontic reasons were included in this study. Following the surgical procedure, the exposed pulp tissue was treated either with calcium silicate or covered with calcium hydroxide paste. On day 3, 7, 14 and 28, the experimental teeth was extracted and examined using light microscopy and histometric analysis to observe the inflammatory changes and the amount of reparative dentin formation. The results showed that in the calcium silicate treated teeth, substantial amounts of dentine-like tissue was formed on day 14 and mostly located on the exposure site. It was also observed in the calcium hydroxide treated teeth but dentin-like tissue located at a distance from the exposure site. The total amount of reparative dentine formed in the calcium silicate-treated teeth was significantly higher (p<0.005) than in the calcium hydroxide-treated specimens. In conclusion that the calcium silicate indices pulpal wound healing and reparative formation in the exposed teeth without affecting the normal function of the remaining pulp.

scholarly journals A New Calcium Silicate-Based Root Canal Dressing: Physical and Chemical Properties, Cytotoxicity and Dentinal Tubule Penetration

2020 ◽  
Vol 31 (6) ◽  
pp. 598-604
Author(s):  
Natália Villa ◽  
Vanessa Valgas Dos Santos ◽  
Ubirajara Maciel da Costa ◽  
Aline Teixeira Mendes ◽  
Pedro Henrique Marks Duarte ◽  
...  
Keyword(s):  
Calcium Hydroxide ◽  
Calcium Ion ◽  
Calcium Silicate ◽  
Chemical Properties ◽  
Dentinal Tubule ◽  
Ion Release ◽  
Tukey Test ◽  
Physical And Chemical ◽  
Tubule Penetration ◽  
And Chemical Properties

Abstract The aims of this study were to evaluate the physical and chemical properties, cytotoxicity and dentinal tubule penetration of a new calcium silicate-based root canal dressing. For pH and calcium ion release evaluation (1, 24, 72 and 168 h) were used a pH meter and colorimetric spectrophotometer, respectively. Radiopacity evaluation followed the ISO 6876:2012. Cytotoxicity was evaluated by the percentage of cell viability using MTT assay. Illustrative images of dentinal tubule penetration were obtained using confocal laser scanning microscopy (CLSM). Data from pH and calcium ion release were statistically analyzed by two-way analysis of variance and Tukey test. Radiopacity was analyzed using the Student t-test. The statistical tests for cytotoxicity results were the one-way analysis of variance and Tukey test. Both materials showed alkaline pH in all experimental times. The pH values for calcium hydroxide paste were higher than bioceramic paste at 1, 24, and 72 h (p<0.05). The calcium ion release of bioceramic was lower than the calcium hydroxide paste only at 24 h (p<0.05). The bioceramic was more radiopaque than the calcium hydroxide paste (p<0.05). Bioceramic paste presented a dose and time-dependent cytotoxic effect after MTT assay. CLSM images showed absence of tubule penetration for both pastes. The new calcium silicate-based canal dressing presented alkaline pH, high calcium release, and acceptable radiopacity. Bio C Temp showed a dose and time-dependent cytotoxic and absence of dentinal tubule penetration.

scholarly journals Cytotoxicity and Bioactivity of Dental Pulp-Capping Agents towards Human Tooth-Pulp Cells: A Systematic Review of In-Vitro Studies and Meta-Analysis of Randomized and Controlled Clinical Trials

Materials ◽  
2020 ◽  
Vol 13 (12) ◽  
pp. 2670 ◽  
Author(s):  
Mariano S. Pedano ◽  
Xin Li ◽  
Kumiko Yoshihara ◽  
Kirsten Van Landuyt ◽  
Bart Van Meerbeek
Keyword(s):  
Calcium Hydroxide ◽  
Calcium Silicate ◽  
Dental Pulp ◽  
Meta Analysis ◽  
Capping Agents ◽  
Human Dental Pulp Cells ◽  
Pulp Capping ◽  
Human Dental Pulp ◽  
Pulp Cells

Background. In the era of biology-driven endodontics, vital pulp therapies are regaining popularity as a valid clinical option to postpone root-canal treatment. In this sense, many different materials are available in the market for pulp-capping purposes. Objectives. The main aim of this systematic review and meta-analysis was to examine literature regarding cytotoxicity and bioactivity of pulp-capping agents by exposure of human dental pulp cells of primary origin to these materials. A secondary objective was to evaluate the inflammatory reaction and reparative dentin-bridge formation induced by the different pulp-capping agents on human pulp tissue. Data sources. A literature search strategy was carried out on PubMed, EMBASE and the Web of Science databases. The last search was done on 1 May 2020. No filters or language restrictions were initially applied. Two researchers independently selected the studies and extracted the data. Study selection included eligibility criteria, participants and interventions, study appraisal and synthesis methods. In vitro studies were included when human dental pulp cells of primary origin were (in) directly exposed to pulp-capping agents. Parallel or split-mouth randomized or controlled clinical trials (RCT or CCT) were selected to investigate the effects of different pulp-capping agents on the inflammation and reparative bridge-formation capacity of human pulp tissue. Data were synthesized via odds ratios (95% confidence interval) with fixed or random effects models, depending on the homogeneity of the studies. The relative risks (95% confidence interval) were presented for the sake of interpretation. Results. In total, 26 in vitro and 30 in vivo studies were included in the systematic review and meta-analysis, respectively. The qualitative analysis of in vitro data suggested that resin-free hydraulic calcium-silicate cements promote cell viability and bioactivity towards human dental pulp cells better than resin-based calcium-silicate cements, glass ionomers and calcium-hydroxide cements. The meta-analysis of the in vivo studies indicated that calcium-hydroxide powder/saline promotes reparative bridge formation better than the popular commercial resin-free calcium-silicate cement Pro-Root MTA (Dentsply-Sirona), although the difference was borderline non-significant (p = 0.06), and better than calcium-hydroxide cements (p < 0.0001). Moreover, resin-free pulp-capping agents fostered the formation of a complete reparative bridge better than resin-based materials (p < 0.001). On the other hand, no difference was found among the different materials tested regarding the inflammatory effect provoked at human pulp tissue. Conclusions. Calcium-hydroxide (CH) powder and Pro-Root MTA (Dentsply-Sirona) have shown excellent biocompatibility in vitro and in vivo when tested on human cells and teeth. Their use after many years of research and clinical experience seems safe and proven for vital pulp therapy in healthy individuals, given that an aseptic environment (rubber dam isolation) is provided. Although in vitro evidence suggests that most modern hydraulic calcium-silicate cements promote bioactivity when exposed to human dental pulp cells, care should be taken when these new materials are clinically applied in patients, as small changes in their composition might have big consequences on their clinical efficacy. Key findings (clinical significance). Pure calcium-hydroxide powder/saline and the commercial resin-free hydraulic calcium-silicate cement Pro-Root MTA (Dentsply-Sirona) are the best options to provide a complete reparative bridge upon vital pulp therapy. Systematic review registration number. PROSPERO registration number: CRD42020164374.

Two calcium silicate-based materials used in direct pulp capping (in-vivo study)

2020 ◽  
Vol 17 (2) ◽  
pp. 78
Author(s):  
MonaM Abdel Sameia ◽  
AbeerM Darrag ◽  
WalaaM Ghoneim
Keyword(s):  
Calcium Silicate ◽  
In Vivo Study ◽  
Direct Pulp Capping ◽  
Pulp Capping ◽  
Materials Used

scholarly journals Theracal lc: A boon to dentistry

2021 ◽  
Vol 11 (2) ◽  
pp. 112-117
Author(s):  
Kalyani G Umale ◽  
Vandana J Gade ◽  
Reema N Asani ◽  
Priya R. Kosare ◽  
Snehal Gaware ◽  
...  
Keyword(s):  
Calcium Hydroxide ◽  
Calcium Silicate ◽  
Tissue Formation ◽  
Hard Tissue ◽  
Setting Reaction ◽  
Pulp Capping ◽  
Composition Method ◽  
Calcium Silicates ◽  
Pulp Vitality ◽  
Postoperative Sensitivity

TheraCal LC, the focus of this article, is a material that creates a new category of resin-modified calcium silicates (RMCS). It is a light-cured, resin-based, and highly radiopaque liner designed to release calcium to promote hard-tissue formation, and is indicated for use under direct restorative materials as a replacement to calcium hydroxide and other calcium silicate-based materials, glass ionomers, eugenol-based sedative materials, and pulp capping restoratives. TheraCal LC exhibits several properties to help maintain ideal hard-tissue health and to reduce the incidence of postoperative sensitivity. This article is aimed to review the composition, method of application, setting reaction, properties and uses of TheraCal LC. TheraCal LC is interesting and promising product, which have the potential of creating major contributions to maintaining pulp vitality.

scholarly journals Histological evaluation of human pulp capped with light-cured calcium based cements: a randomized controlled clinical trial

2017 ◽  
Vol 3 (5) ◽  
pp. 120 ◽  
Author(s):  
G. Jeya Gopika ◽  
Sathyanarayanan Ramarao ◽  
Carounanidy Usha ◽  
Bindu Meera John ◽  
N. Vezhavendhan
Keyword(s):  
Inflammatory Response ◽  
Calcium Hydroxide ◽  
Calcium Silicate ◽  
Permanent Teeth ◽  
Histological Evaluation ◽  
Controlled Clinical Trial ◽  
Direct Pulp Capping ◽  
Hard Tissue ◽  
Pulp Capping ◽  
Reparative Dentin

<p><strong>Background: </strong>Calcium hydroxide has traditionally been used as the pulp capping material for pulpal exposures in permanent teeth. The tunnel defects in the barrier and the tendency for dissolution, however, fails to provide permanent protection to the pulp. Light curable resin based cements have been introduced to enable a better marginal seal and lesser dissolution. The purpose of this study was to compare and evaluate the response of human pulp following direct pulp capping with the new resin based Calcium silicate (TheraCal LC) and Calcium hydroxide with hydroxyapatite (Septocal LC) cements compared with calcium hydroxide (Dycal). <strong></strong></p><p><strong>Methods: </strong>72 intact human premolars scheduled for orthodontic extractions were exposed to direct pulp capping procedures using three different pulp capping agents. Teeth were randomly divided into 3 groups, Group A: Dycal, Group B: TheraCal LC, Group C: Septocal LC. The teeth were extracted at the end of 15 and 40 days’ and were evaluated histologically. They were scored for reparative dentin formation and inflammatory response. Inferential statistics was done using Chi square test<strong>. </strong><strong></strong></p><p><strong>Results: </strong>Majority of the specimens in all three groups at the end of 15 days’ showed partial to lateral deposition of hard tissue. There was continuous deposition of hard tissue and severe inflammatory response at the end of 40 days’ in Dycal. There was partial deposition of hard tissue and reduced inflammatory response at the end of 40 days’ in TheraCal LC and Septocal LC. However, the results were not statistically significant between the three groups at two different time periods. <strong></strong></p><p><strong>Conclusions: </strong>Light cured,<strong> </strong>Calcium silicate (TheraCal LC) and Calcium hydroxide with hydroxyapatite (Septocal LC) cements were as effective as calcium hydroxide (Dycal) in inducing the formation of reparative dentin and evoking inflammatory response.</p>

scholarly journals Mineral Trioxide Aggregate Versus Calcium Hydroxide in Direct Pulp Capping: A Review of Literature

2020 ◽  
Vol 5 (07) ◽  
Author(s):  
Abdullah Mohammed Alrabiah
Keyword(s):  
Success Rate ◽  
Calcium Hydroxide ◽  
Mineral Trioxide Aggregate ◽  
Cost Effective ◽  
Long Term Results ◽  
Glass Ionomer ◽  
Direct Pulp Capping ◽  
Pulp Capping ◽  
Materials Used

Direct pulp-capping is a treatment for exposed vital pulp involving the placement of a dental material over the exposed area. This facilitates both the formation of protective barrier and the maintenance of vital pulp. Direct pulp capping (DPC) has been used as an alternative approach to the maintenance of vital pulp. So, many tooth extractions and root canal treatments could have been avoided through the conservative approach of direct pulp capping. For this purpose, different kinds of materials used such as Zinc Oxide Eugenol, Glass Ionomer (GI), Resin Modified Glass Ionomer (RMGI), Adhesive systems, Calcium Hydroxide (CH), Mineral Trioxide Aggregate (MTA) and Bio dentine. MTA performed more effective than conventional Calcium Hydroxide clinically as a direct pulp capping material. MTA showed higher success rate than dycal. MTA is easier to use clinically as a direct pulp capping material. MTA also provided better long-term results and more effective than Calcium Hydroxide in maintaining long-term vitality. MAT is significantly less toxic, less pulpal inflammations. Furthermore, MTA is more predictable than dycal in formation of dentin barrier and superior than Calcium Hydroxide in dentinogenetic process in human pulp. MTA is more effective and superior comparing the Calcium Hydroxide as a direct pulp capping material, demonstrating higher success rate with favorable outcomes in maintaining long term tooth vitality and easier to use in pulp capping. Finally, MTA is more cost-effective than CH for DPC despite higher initial treatment costs because expensive retreatments were avoided.

scholarly journals Calcium silicate and calcium hydroxide materials for pulp capping: biointeractivity, porosity, solubility and bioactivity of current formulations

2014 ◽  
Vol 13 (1) ◽  
pp. 0-0 ◽  
Author(s):  
Maria Giovanna Gandolfi ◽  
Francesco Siboni ◽  
Tatiana Botero ◽  
Maurizio Bossù ◽  
Francesco Riccitiello ◽  
...  
Keyword(s):  
Calcium Hydroxide ◽  
Calcium Silicate ◽  
Pulp Capping

scholarly journals Study on modification mechanism of workability and mechanical properties for graphene oxide-reinforced cement composite

2020 ◽  
Vol 10 ◽  
pp. 184798042091260
Author(s):  
Yuxia Suo ◽  
Rongxin Guo ◽  
Haiting Xia ◽  
Yang Yang ◽  
Feng Yan ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Compressive Strength ◽  
Graphene Oxide ◽  
Calcium Hydroxide ◽  
Calcium Silicate ◽  
Calcium Silicate Hydrate ◽  
Inverse Correlation ◽  
Cement Composite ◽  
Hydration Reaction ◽  
Cement Pastes

Graphene oxide/cement composite was prepared using a graphene oxide aqueous solution. The workability and mechanical properties of graphene oxide/cement composite with different concentrations for graphene oxide and the ratio of water to cement were investigated. The results observed were the fluidity of cement pastes decreased noticeably with the addition of graphene oxide and increased with the increase in the ratio of water to cement for all tested samples of different graphene oxide contents. It is indicated that a noticeable inverse correlation between the concentration of graphene oxide and fluidity was observed, and a positive linear relationship between the ratio of water to cement and fluidity was also obtained. The compressive strength of cement pastes significantly improved in the presence of an appropriate concentration of graphene oxide as compared to that of the cement paste without graphene oxide; this difference was due to the denser microstructure of graphene oxide/cement composite than that of the control specimens. With the combined analysis of X-ray diffraction and scanning electron microscopy with energy-dispersive spectrometry, the results showed that graphene oxide could promote and regulate the formation and connection of calcium hydroxide and calcium silicate hydrate during the hydration reaction, forming numerous regular and extremely compact plate-shaped crystals, and the compact plate-shaped microstructures constituted of not only calcium hydroxide and calcium silicate hydrate but also wrapped ettringite. This investigation will provide a flexible way to preparation of graphene oxide/cement composite with wanted fluidity and optimized compressive strength that promote the industry application of graphene oxide/cement composite.

Sign in / Sign up

Export Citation Format

Share Document