scholarly journals Dispensing patterns of medicines prescribed by Australian dentists from 2006 to 2018 – a pharmacoepidemiological study

2020 ◽  
Author(s):  
Joon Soo Park ◽  
Amy T. Page ◽  
Estie Kruger ◽  
Marc Tennant
Keyword(s):  
Pharmacoepidemiological Study

A pharmacoepidemiological study of the consumption of antiparkinson drugs in the Basque Autonomous Community (Spain) (1992–2004)

2007 ◽  
Vol 13 (8) ◽  
pp. 500-504 ◽  
Author(s):  
Eider Abasolo Osinaga ◽  
Luis Carlos Abecia Inchaurregui ◽  
Itziar Etxeandia Ikobaltzeta ◽  
Natalia Burgos Alonso ◽  
Javier García del Pozo
Keyword(s):  
Autonomous Community ◽  
Pharmacoepidemiological Study ◽  
Antiparkinson Drugs

Atrial fibrillation in patients treated with intravenous zoledronic or pamidronic acid: a pharmacoepidemiological study

2021 ◽  
Vol 184 (3) ◽  
pp. 441-448
Author(s):  
Luc Pijnenburg ◽  
Joe-Elie Salem ◽  
Bénédicte Lebrun-Vignes ◽  
Jean Sibilia ◽  
Rose-Marie Javier ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Zoledronic Acid ◽  
Pamidronic Acid ◽  
Real Life ◽  
World Health ◽  
Disproportionality Analysis ◽  
Pharmacoepidemiological Study ◽  
Systematic Analysis ◽  
The World ◽  
Pharmacovigilance Database

Objective Atrial fibrillation (AF) may be triggered by intravenous bisphosphonates (IVBPs) such as zoledronic acid or pamidronic acid. Our objective was to confirm the association between AF and IVBPs in a real-life large pharmacovigilance database. Design A systematic analysis of VigiBase, the World Health Organization's pharmacovigilance database. Methods Analysis of adverse events reported as ‘atrial fibrillation’ (according to the Medical Dictionary for Drug Regulatory Activities) associated with the use of zoledronic acid or pamidronic acid, in VigiBase, the World Health Organization's global Individual Case Safety Report (ICSR) database. All ICSRs reporting AF associated with zoledronic acid or pamidronic acid were included in a disproportionality analysis determining the lower end of the 95% credibility interval for the information component (IC025), showing a statistical association when >0. Results 530 ICSRs reporting on the association between AF and IVBPs were extracted. Bayesian disproportionality analysis detected a significant association between AF and use of zoledronic acid (IC025 = 1.83) and pamidronic acid (IC025 = 2.16). Further analysis of these ICSRs determined that AF was severe in 85.0% of cases and with a mortality of 17.7%. The risk of severe AF was increased (OR: 2.98 (95% CI: 1.17–7.57), P = 0.02) following zoledronic acid vs pamidronic acid, after adjustment for age and gender. Conclusions This is the first VigiBase pharmacoepidemiological study confirming the association between IVBPs and AF. Most AF were severe, with a high frequency of lethal outcome. The risk of severe AF was increased following zoledronic acid use compared to pamidronic acid, advocating for a cautious use of IVBPs.

scholarly journals Seeking prescribing patterns in rural Crete: a pharmacoepidemiological study from a primary care area

2006 ◽  
Author(s):  
Nikos Antonakis ◽  
Irene Xylouri ◽  
Michalis Alexandrakis ◽  
Catherine Cavoura ◽  
Christos Lionis
Keyword(s):  
Primary Care ◽  
Prescribing Patterns ◽  
Pharmacoepidemiological Study

scholarly journals Web-based questionnaires: Lessons learned from practical implementation of a pharmacoepidemiological study

F1000Research ◽  
2017 ◽  
Vol 6 ◽  
pp. 135
Author(s):  
Raissa Cândido ◽  
Edson Perini ◽  
Cristiane Menezes de Pádua ◽  
Daniela Junqueira
Keyword(s):  
Data Collection ◽  
Information Science ◽  
Cognitive Enhancement ◽  
Lessons Learned ◽  
Practical Implementation ◽  
Considerable Effort ◽  
Pharmacoepidemiological Study ◽  
Web Based ◽  
Respondent Burden ◽  
Online Mode

Web-based questionnaires may offer advantages over traditional methods of data collection, including a less administrative workload and reduced respondent burden. However, the implementation of this mode of data collection carries other challenges and may demand more technical expertise to be designed and delivered. Here, we use the preliminary data from a survey developed to estimate the prevalence of methylphenidate use for cognitive enhancement among undergraduate and graduate students, to share the lessons we learned while implementing this online mode of data collection. We show that surveys using a web-based questionnaire should be carried out by a multidisciplinary team with support from Information Science specialists. Limitations to access these resources or budget constraints may demand a considerable effort to assure the success of the survey. Web-questionnaires are usually described as easy to use and economically encouraging. Therefore, we believe our experience, and the lessons we learned, may be a relevant resource for researchers from general backgrounds intending to undertake their first web-questionnaire.

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