scholarly journals Structural changes in dermal collagen and oxidative stress levels in the skin of Japanese overweight males

2014 ◽  
Vol 36 (5) ◽  
pp. 477-484 ◽  
Author(s):  
M. Matsumoto ◽  
A. Ibuki ◽  
T. Minematsu ◽  
J. Sugama ◽  
M. Horii ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Structural Changes ◽  
Stress Levels ◽  
Dermal Collagen ◽  
And Oxidative Stress

scholarly journals RNA-Seq Expression Analysis of Chronic Asthmatic Mice with Bu-Shen-Yi-Qi Formula Treatment and Prediction of Regulated Gene Targets of Anti-Airway Remodeling

2021 ◽  
Vol 2021 ◽  
pp. 1-9
Author(s):  
Jie Cui ◽  
Zexi Lv ◽  
Fangzhou Teng ◽  
La Yi ◽  
Weifeng Tang ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Gene Network ◽  
Structural Changes ◽  
Airway Remodeling ◽  
Signal Pathways ◽  
Rna Seq ◽  
Critical Nodes ◽  
Differential Expression Genes ◽  
Polymerase Chain ◽  
And Oxidative Stress

Airway remodeling is one of the typical pathological characteristics of asthma, while the structural changes of the airways in asthma are complex, which impedes the development of novel asthma targeted therapy. Our previous study had shown that Bu-Shen-Yi-Qi formula (BSYQF) could ameliorate airway remodeling in chronic asthmatic mice by modulating airway inflammation and oxidative stress in the lung. In this study, we analysed the lung transcriptome of control mice and asthmatic mouse model with/without BSYQF treatment. Using RNA-sequencing (RNA-seq) analysis, we found that 264/1746 (15.1%) of transcripts showing abnormal expression in asthmatic mice were reverted back to completely or partially normal levels by BSYQF treatment. Additionally, based on previous results, we identified 21 differential expression genes (DEGs) with fold changes (FC) > (±) 2.0 related to inflammatory, oxidative stress, mitochondria, PI3K/AKT, and MAPK signal pathways which may play important roles in the mechanism of the anti-remodeling effect of BSYQF treatment. Through inputting 21 DEGs into the IPA database to construct a gene network, we inferred Adipoq, SPP1, and TNC which were located at critical nodes in the network may be key regulators of BSYQF's anti-remodeling effect. In addition, the quantitative real-time polymerase chain reaction (qRT-PCR) result for the selected four DEGs matched those of the RNA-seq analysis. Our results provide a preliminary clue to the molecular mechanism of the anti-remodeling effect of BSYQF in asthma.

Xanthine oxidoreductase polymorphisms: influence in blood pressure and oxidative stress levels

2007 ◽  
Vol 17 (8) ◽  
pp. 589-596 ◽  
Author(s):  
Felipe J. Chaves ◽  
Dolores Corella ◽  
Sebastian Blesa ◽  
Maria L. Mansego ◽  
Pablo Marín ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Blood Pressure ◽  
Xanthine Oxidoreductase ◽  
Stress Levels ◽  
And Oxidative Stress

scholarly journals Relationship between serum DHEAS and oxidative stress levels of body mass index in healthy postmenopausal women

Redox Report ◽  
2016 ◽  
Vol 21 (2) ◽  
pp. 61-66 ◽  
Author(s):  
Burhan Goy ◽  
Murat Atmaca ◽  
Mehmet Aslan ◽  
Rıfkı Ucler ◽  
Murat Alay ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Body Mass Index ◽  
Postmenopausal Women ◽  
Body Mass ◽  
Stress Levels ◽  
And Oxidative Stress

Seminal plasma oxytocin and oxidative stress levels in infertile men with varicocele

Andrologia ◽  
2014 ◽  
Vol 47 (2) ◽  
pp. 209-213 ◽  
Author(s):  
T. Mostafa ◽  
L. A. Rashed ◽  
I. Osman ◽  
M. Marawan
Keyword(s):  
Oxidative Stress ◽  
Seminal Plasma ◽  
Infertile Men ◽  
Stress Levels ◽  
And Oxidative Stress

scholarly journals Association of mid-pregnancy antioxidative vitamin and oxidative stress levels with infant growth during the first 3 years of life

2014 ◽  
Vol 58 (1) ◽  
pp. 20207 ◽  
Author(s):  
Juhee Hong ◽  
Hye Ah Lee ◽  
Eun Ae Park ◽  
Young-Ju Kim ◽  
Hwayoung Lee ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Infant Growth ◽  
Stress Levels ◽  
And Oxidative Stress

Electrolyte, Nitric Oxide and Oxidative Stress Levels of Aqueous Humor in Patients with Retinal Detachment and Silicone Oil Tamponade

2020 ◽  
Vol 45 (11) ◽  
pp. 1443-1450
Author(s):  
Meltem Ece Kars ◽  
Yasin Toklu ◽  
Mücella Arıkan Yorgun ◽  
Salim Neşelioğlu ◽  
Funda Eren
Keyword(s):  
Oxidative Stress ◽  
Nitric Oxide ◽  
Retinal Detachment ◽  
Aqueous Humor ◽  
Silicone Oil ◽  
Stress Levels ◽  
Silicone Oil Tamponade ◽  
And Oxidative Stress
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