scholarly journals Performance of serum α-fetoprotein levels in the diagnosis of hepatocellular carcinoma in patients with a hepatic mass

HPB ◽  
2014 ◽  
Vol 16 (4) ◽  
pp. 366-372 ◽  
Author(s):  
Stephen L. Chan ◽  
Frankie Mo ◽  
Philip J. Johnson ◽  
Deyond Y.W. Siu ◽  
Michael H.M. Chan ◽  
...  
2021 ◽  
Vol 0 (0) ◽  
pp. 0
Author(s):  
Philippe Ah-Soune ◽  
Ludivine Gan ◽  
Fanny Houser ◽  
Thomas Di Bernardo ◽  
Aude Le Goffic

2016 ◽  
Vol 111 ◽  
pp. S935-S936
Author(s):  
Roshni Narurkar ◽  
Lakshmi Asritha Gollapudi ◽  
Vipin Mittal ◽  
David Wolf

2017 ◽  
Vol 3 (1) ◽  
pp. 205511691770665
Author(s):  
Lara Boland ◽  
Scott Lindsay ◽  
Laurencie Brunel ◽  
Juan Podadera ◽  
Peter Bennett

Case summary A 17-year-old female neutered domestic shorthair cat presented for several days of reduced faecal volume and a rectal prolapse. Physical examination revealed a 2 cm rectal prolapse, hepatomegaly and a low body condition score of 3/9. Haematology and biochemistry revealed a mild non-regenerative anaemia (haematocrit 24.5%; reference interval [RI] 30.3–52.3%), a mild mature neutrophilia (16.21 × 109/l; RI 1.48–10.29 × 109/l) and a mild increase in alanine aminotransferase activity (222 IU/l; RI 12–130 IU/l). Abdominal radiographs identified hepatomegaly. The rectal prolapse was reduced under general anaesthesia. Abdominal ultrasound identified a caecocolic intussusception and a large hepatic mass. Thoracic radiographs were unremarkable. Hepatic fine-needle aspirate cytology revealed well-differentiated hepatocytes. A typhlectomy was performed and the quadrate liver lobe, with mass, was resected. Gross examination of the caecum identified a focal polyp; histopathology showed moderate plasmacytic–lymphocytic typhlitis and reactive mucosal-associated lymphoid tissue. The hepatic mass was diagnosed as a well-differentiated hepatocellular carcinoma. Six weeks postoperatively the cat had gained 0.5 kg, had an improved body condition score of 5/9 and resolution of clinical signs. The cat died acutely 1 year later from an unknown cause. Relevance and novel information Caecocolic intussusception is rare in cats and uncommon in dogs. This is the third report in a cat and the first associated with a caecal polyp. As reported in dogs, the outcome following surgery was good. Hepatocellular carcinoma is a rarely reported feline neoplasm, which may have a good prognosis with surgical resection.


Diagnostics ◽  
2021 ◽  
Vol 12 (1) ◽  
pp. 44
Author(s):  
Teodoro Rudolphi-Solero ◽  
Eva María Triviño-Ibáñez ◽  
Antonio Medina-Benítez ◽  
Javier Fernández-Fernández ◽  
Daniel José Rivas-Navas ◽  
...  

Fibrolamellar hepatocellular carcinoma is a primary hepatic tumor that usually appears in young adults. Radical surgery is considered curative for this kind of tumor, so early diagnosis becomes essential for the prognosis of the patients. The main characteristic of this entity is the central scar, which is the center of differential diagnosis. We report the case of a 30-year-old man who was diagnosed with fibrolamellar hepatocellular carcinoma by ultrasonography. Contrast-enhanced CT confirmed this diagnosis, and the patient underwent a [18F] fluorocholine PET/CT. Hypermetabolism and the morphology in the nuclear medicine exploration suggest neoplastic nature of the lesion. Radical surgery was performed, and histopathologic analysis was performed, which resulted in focal nodular hyperplasia. Hepatic masses with central scar could have a difficult differential diagnosis, and focal nodular hyperplasia could mimic fibrolamellar hepatocellular carcinoma imaging patterns. These morphofunctional characteristics have not been described in [18F] Fluorocholine PET/CT, so there is a need to find out the potential role PET/CT in the differential diagnosis of hepatic mass with central scar.


1998 ◽  
Vol 13 (11-s4) ◽  
pp. S315-S319 ◽  
Author(s):  
ZHAO-YOU TANG ◽  
XIN-DA ZHOU ◽  
ZENG-CHEN MA ◽  
ZHI-QUAN WU ◽  
JIA FAN ◽  
...  

1982 ◽  
Vol 118 (1) ◽  
pp. 69-70 ◽  
Author(s):  
A. J. Bennett

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