HIV viraemia and mother-to-child transmission risk after antiretroviral therapy initiation in pregnancy in Cape Town, South Africa

HIV Medicine ◽  
2016 ◽  
Vol 18 (2) ◽  
pp. 80-88 ◽  
Author(s):  
L Myer ◽  
TK Phillips ◽  
JA McIntyre ◽  
N-Y Hsiao ◽  
G Petro ◽  
...  
Keyword(s):  
South Africa ◽  
Antiretroviral Therapy ◽  
Cape Town ◽  
Transmission Risk ◽  
Mother To Child Transmission ◽  
Child Transmission ◽  
Therapy Initiation ◽  
Mother To Child ◽  
In Pregnancy

HIV incidence during breastfeeding and mother-to-child transmission in Cape Town, South Africa

AIDS ◽  
2019 ◽  
Vol 33 (8) ◽  
pp. 1399-1401 ◽  
Author(s):  
Stanzi M. le Roux ◽  
Elaine J. Abrams ◽  
Kelly K. Nguyen ◽  
Landon Myer
Keyword(s):  
South Africa ◽  
Cape Town ◽  
Hiv Incidence ◽  
Mother To Child Transmission ◽  
Child Transmission ◽  
Mother To Child

scholarly journals Prevention of mother-to-child HIV transmission: from the first stages to the possibility of elimination

2021 ◽  
Vol 69 (6) ◽  
pp. 107-116
Author(s):  
Olga L. Mozalyova ◽  
Anna V. Samarina
Keyword(s):  
Antiretroviral Therapy ◽  
Highly Active Antiretroviral Therapy ◽  
Hiv Transmission ◽  
Transmission Rate ◽  
Preventive Treatment ◽  
Transmission Risk ◽  
Mother To Child Transmission ◽  
Child Transmission ◽  
Perinatal Hiv ◽  
Mother To Child

Despite the success in reducing mother-to-child HIV transmission rate worldwide, the problem of perinatal HIV transmission is still relevant. Sexual activity nowadays is the predominant way of transmission, therefore the number of HIV cases among women growths. This leads to an increased number of pregnancies and childbirth in HIV-infected women. Better preventive treatment has decreased the transmission risk to 1% or less. Despite this, the Russian Federation is still not among the countries where the elimination of mother-to-child transmission has been recorded. This review article focuses on the main stages of mother-to-child transmission prevention from the time that no antiretroviral therapy was available to the current stage, when highly active antiretroviral therapy is used during pregnancy, childbirth and for the treatment of newborns. The research provides a comparative analysis of modern national and international clinical recommendations for the prevention of mother-to-child HIV transmission.

scholarly journals Prevention of mother-to-child transmission in South Africa: an ever-changing landscape

2015 ◽  
Vol 8 (1) ◽  
pp. 5-12 ◽  
Author(s):  
Rosie Burton ◽  
Janet Giddy ◽  
Kathryn Stinson
Keyword(s):  
South Africa ◽  
Antiretroviral Therapy ◽  
Substantial Reduction ◽  
Hiv Treatment ◽  
Mother To Child Transmission ◽  
Child Transmission ◽  
Hiv Epidemic ◽  
The Government ◽  
The Impact ◽  
Mother To Child

Almost 30% of pregnant women attending public health clinics in South Africa are HIV positive; which represents approximately 280,000 women each year. South Africa has the largest antiretroviral therapy programme in the world, with over 2.7 million people on treatment in 2013. Since its belated and controversial beginning, the Prevention of Mother-to-Child Transmission programme has achieved a substantial reduction in vertical transmission. South Africa is justifiably proud of this success. However, the history of Prevention of Mother-to-Child Transmission (PMTCT) and antiretroviral therapy programmes in South Africa has been fraught with delays and political intervention. South Africa could have started both PMTCT and antiretroviral therapy programmes in 2000. Instead, the AIDS denialist views of the government allowed the HIV epidemic to spiral out of control. Roll-out of a national PMTCT programme began in 2002, but only after the government was forced to do so by a Constitutional Court ruling. Now, a decade later, HIV treatment and prevention programmes have been completely transformed. This article will discuss the evolution of the HIV epidemic in South Africa, and give a historical overview of the struggle to establish a national PMTCT, and the impact of delaying PMTCT and treatment programmes on infant and maternal health.

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