ALK rearrangements in infantile fibrosarcoma‐like spindle cell tumors of soft tissue and kidney

2021 ◽  
Author(s):  
Serena Y. Tan ◽  
Alyaa Al‐Ibraheemi ◽  
William A. Arhens ◽  
Javier E. Oesterheld ◽  
Julie C. Fanburg‐Smith ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Spindle Cell ◽  
Infantile Fibrosarcoma ◽  
Spindle Cell Tumors

Spindle cell tumors of bone and soft tissue in infants and children

2013 ◽  
pp. 23-40
Author(s):  
Lester J. Layfield ◽  
Carlos W. Bedrossian ◽  
Julia R. Crim ◽  
Lucio Palombini
Keyword(s):  
Soft Tissue ◽  
Spindle Cell ◽  
Infants And Children ◽  
Tumors Of Bone ◽  
Spindle Cell Tumors ◽  
In Infants And Children

SMOOTH AND SKELETAL MUSCLE MYOSINS IN SPINDLE CELL TUMORS OF SOFT TISSUE

1985 ◽  
Vol 35 (1) ◽  
pp. 125-136 ◽  
Author(s):  
Takashi Saku ◽  
Nobuo Tsuda ◽  
Masanobu Anami ◽  
Haruo Okabe
Keyword(s):  
Skeletal Muscle ◽  
Soft Tissue ◽  
Spindle Cell ◽  
Spindle Cell Tumors

scholarly journals The histologic spectrum of soft tissue spindle cell tumors with NTRK3 gene rearrangements

2019 ◽  
Vol 58 (11) ◽  
pp. 739-746 ◽  
Author(s):  
Albert J. Suurmeijer ◽  
Brendan C. Dickson ◽  
David Swanson ◽  
Lei Zhang ◽  
Yun‐Shao Sung ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Spindle Cell ◽  
Gene Rearrangements ◽  
Spindle Cell Tumors

scholarly journals Bovine Papillomavirus DNA and S100 Profiles in Sarcoids and Other Cutaneous Spindle Cell Tumors in Horses

2016 ◽  
Vol 54 (1) ◽  
pp. 44-52 ◽  
Author(s):  
E. D. Epperson ◽  
W. L. Castleman
Keyword(s):  
Soft Tissue ◽  
Spindle Cell ◽  
Soft Tissue Sarcomas ◽  
Soft Tissue Tumors ◽  
Bovine Papillomavirus ◽  
Nerve Sheath Tumor ◽  
Peripheral Nerve Sheath Tumors ◽  
Nerve Sheath ◽  
Spindle Cell Tumors ◽  
Tumor Types

Histopathologic differentiation between deep dermal or subcuticular equine sarcoids (ie, nodular sarcoids) and other spindle cell tumors in the dermis and subcutis such as peripheral nerve sheath tumors (PNSTs) can be challenging based on morphologic criteria alone. It has been proposed that polymerase chain reaction (PCR) for bovine papillomavirus (BPV) DNA and S100 immunohistochemistry be used as diagnostic tests to separate equine sarcoids from PNSTs. We reviewed 197 skin-associated spindle cell tumors (ie, soft tissue sarcomas), including PNSTs and sarcoids, received at the University of Florida between 1995 and 2013 and performed BPV PCR and S100 immunohistochemistry on archived paraffin-embedded tissues. We found that BPV DNA was demonstrable in 70% of the sarcoids, 59% of the PNSTs, 37% of the fibrosarcomas, and 22% of other tumors (myxosarcomas, fibromas, and other sarcomas) diagnosed on histomorphologic characteristics. Positive S100 staining was only seen in 12 tumors in the study (5 fibrosarcomas, 3 sarcoids, 2 PNSTs, and 2 other sarcomas). The results demonstrate that BPV is associated with many skin-associated spindle cell soft tissue tumors in horses in addition to sarcoids. S100 was rarely expressed in equine soft tissue sarcomas in the skin but was expressed in many tumor types, including PNSTs and sarcoids. Because 41% of the PNSTs classified by histomorphology in this study were BPV negative and 94% were S100 negative, it is reasonable to classify these as soft tissue sarcomas with nerve sheath tumor histomorphology rather than as either PNSTs or sarcoids.

Inflammatory Myofibroblastic Tumour in Antimesenteric Border of Descending Colon of Children: A Case Report

2015 ◽  
Vol 3 (1) ◽  
pp. 47-50
Author(s):  
Shahnoor Islam ◽  
AKM Amirul Morshed ◽  
Afiqul Islam
Keyword(s):  
Soft Tissue ◽  
Spindle Cell ◽  
Inflammatory Myofibroblastic Tumour ◽  
Pathological Findings ◽  
Soft Tissue Lesion ◽  
Soft Tissue Tumours ◽  
Inflammatory Pseudotumour ◽  
Erythrocyte Sedimentation ◽  
Antimesenteric Border

Inflammatory myofibroblastic tumour (IMT) occurring at intraabdominal sites in children has rarely been described. Inflammatory pseudotumour is a soft tissue lesion that may be confused with a sarcoma. It is abbreviated as IMT. Inflammatory myofibroblastic tumour, also known as soft tissue tumours, atypical fibromyxoid tumours, pseudosarcomatous fibromyxoid tumour, plasma cell granuloma, pseudosarcomatous myofibrotic proliferation, post-operative spindle cell nodules. In this paper, we describe a case of inflammatory myofibroblastic tumour (IMT) with an unusual constellation of clinical, pathological findings. A 10-year-old girl had an 7-cm intraabdominal mass accompanied by severe anemia, fever, constipation, weight loss, thrombocytosis, elevated erythrocyte sedimentation rate. Laparotomy was performed. The final pathologic diagnosis was IMT. At the most recent follow up (12months) after excision of the tumour, the patient was symptom-free and there was no evidence of tumour recurrence.J. Paediatr. Surg. Bangladesh 3(1): 47-50, 2012 (January)

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