scholarly journals Src homology phosphotyrosyl phosphatase-2 expression is an independent negative prognostic factor in human breast cancer

2013 ◽  
Vol 63 (1) ◽  
pp. 74-82 ◽  
Author(s):  
Simone Muenst ◽  
Ellen C Obermann ◽  
Feng Gao ◽  
Daniel Oertli ◽  
Carsten T Viehl ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Prognostic Factor ◽  
Human Breast Cancer ◽  
Human Breast ◽  
Negative Prognostic Factor ◽  
Src Homology ◽  
Independent Negative Prognostic Factor

Age at menarche as a prognostic factor in human breast cancer

1976 ◽  
Vol 12 (9) ◽  
pp. 701-704 ◽  
Author(s):  
P. Juret ◽  
J.E. Couette ◽  
A.M. Mandard ◽  
A. Carré ◽  
T. Delozier ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Prognostic Factor ◽  
Human Breast Cancer ◽  
Age At Menarche ◽  
Human Breast

scholarly journals Nuclear Expression of Snail Is an Independent Negative Prognostic Factor in Human Breast Cancer

2013 ◽  
Vol 35 ◽  
pp. 337-344 ◽  
Author(s):  
S. Muenst ◽  
S. Däster ◽  
E. C. Obermann ◽  
R. A. Droeser ◽  
W. P. Weber ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Prognostic Factor ◽  
Human Cancer ◽  
Lymph Node Status ◽  
Intrinsic Subtypes ◽  
Snail Expression ◽  
Mesenchymal Transition ◽  
Luminal B ◽  
Negative Prognostic Factor ◽  
Independent Negative Prognostic Factor

Background. Snail is a key regulator of epithelial-mesenchymal transition of tumor cells. Several studies have shown nuclear Snail expression to be a negative prognostic factor in human cancer, where it is generally associated with more aggressive tumor behavior and worse survival.Objectives and Methods. To further explore the role of Snail expression in breast cancer, we conducted a study on a tissue microarray, encompassing 1043 breast cancer cases.Results. A total of 265 (25.4%) breast cancers were positive for Snail. Snail expression was significantly associated with greater tumor size, higher tumor stage and grade, positive lymph node status, and hormone receptor negative status and was differently expressed in the intrinsic subtypes of breast cancer, being the highest in the basal-like subtype and the lowest in the luminal A subtype. In multivariate analysis, Snail proved to be an independent negative prognostic factor for OS. In the intrinsic subtypes, Snail expression was a negative prognostic factor for OS in the luminal B HER2−, the luminal B HER2+, and the basal-like subtype.Conclusions. This is the first study demonstrating that nuclear Snail expression is an independent negative predictor of prognosis in breast cancer, thus suggesting that it may represent a potential therapeutic target.

Comparison of immunohistochemistry and RT-PCR for detection of CD44v-expression, a new prognostic factor in human breast cancer

1995 ◽  
Vol 60 (4) ◽  
pp. 471-477 ◽  
Author(s):  
Peter Dall ◽  
Karl-Heinz Heider ◽  
Hans-Peter Sinn ◽  
Petra Skroch-Angel ◽  
GÜNther Adolf ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Prognostic Factor ◽  
Human Breast Cancer ◽  
Human Breast ◽  
Rt Pcr

scholarly journals FOXA1: Growth inhibitor and a favorable prognostic factor in human breast cancer

2006 ◽  
Vol 120 (5) ◽  
pp. 1013-1022 ◽  
Author(s):  
Ido Wolf ◽  
Shikha Bose ◽  
Elizabeth A. Williamson ◽  
Carl W. Miller ◽  
Beth Y. Karlan ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Prognostic Factor ◽  
Human Breast Cancer ◽  
Growth Inhibitor ◽  
Human Breast ◽  
Favorable Prognostic Factor

Hyperphosphorylation of translational repressor 4E-BP1 as prognostic factor in human breast cancer

2006 ◽  
Vol 4 (2) ◽  
pp. 145
Author(s):  
M.D. Sabadell ◽  
Rojo ◽  
J. Lirola ◽  
J. Jimenez ◽  
O. Cordoba ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Prognostic Factor ◽  
Human Breast Cancer ◽  
Human Breast ◽  
Translational Repressor

Brief communications oncogene amplification per se: An independent prognostic factor in human breast cancer

1994 ◽  
Vol 11 (4) ◽  
pp. 189-191 ◽  
Author(s):  
Marie-Hélène Champème ◽  
Ivan Biéche ◽  
Kamel Hacéne ◽  
Rosette Lidereau
Keyword(s):  
Breast Cancer ◽  
Prognostic Factor ◽  
Human Breast Cancer ◽  
Independent Prognostic Factor ◽  
Human Breast ◽  
Oncogene Amplification ◽  
Per Se

scholarly journals PTP1B expression is an independent positive prognostic factor in human breast cancer

2012 ◽  
Vol 137 (2) ◽  
pp. 637-644 ◽  
Author(s):  
S. Soysal ◽  
E. C. Obermann ◽  
F. Gao ◽  
D. Oertli ◽  
W. E. Gillanders ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Prognostic Factor ◽  
Human Breast Cancer ◽  
Human Breast
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