scholarly journals The development of search filters for adverse effects of surgical interventions in medline and Embase

2018 ◽  
Vol 35 (2) ◽  
pp. 121-129 ◽  
Author(s):  
Su Golder ◽  
Kath Wright ◽  
Yoon Kong Loke
Keyword(s):  
Adverse Effects ◽  
Surgical Interventions ◽  
Search Filters

scholarly journals Naming Specific Adverse Effects Improves Relative Recall for Search Filters Identifying Literature on Surgical Interventions in MEDLINE and Embase

2019 ◽  
Vol 14 (1) ◽  
pp. 65-67
Author(s):  
Ann Glusker
Keyword(s):  
Adverse Effects ◽  
Systematic Reviews ◽  
Mesh Term ◽  
Search Strategies ◽  
User Engagement ◽  
Discussion Section ◽  
Surgical Interventions ◽  
Search Terms ◽  
Search Filters ◽  
Specific Search

A Review of: Golder, S., Wright, K., & Loke, Y.K. (2018). The development of search filters for adverse effects of surgical interventions in MEDLINE and Embase. Health Information and Libraries Journal, 35(2), 121-129. https://doi.org/10.1111/hir.12213 Abstract Objective – “To develop and validate search filters for MEDLINE and Embase for the adverse effects of surgical interventions” (p.121). Design – From a universe of systematic reviews, the authors created “an unselected cohort…where relevant articles are not chosen because of the presence of adverse effects terms” (p.123). The studies referenced in the cohort reviews were extracted to create an overall citation set. From this, three equal-sized sets of studies were created by random selection, and used for: development of a filter (identifying search terms); evaluation of the filter (testing how well it worked); and validation of the filter (assessing how well it retrieved relevant studies). Setting – Systematic reviews of adverse effects from the Database of Abstracts of Reviews of Effects (DARE), published in 2014. Subjects – 358 studies derived from the references of 19 systematic reviews (352 available in MEDLINE, 348 available in Embase). Methods – Word and phrase frequency analysis was performed on the development set of articles to identify a list of terms, starting with the term creating the highest recall from titles and abstracts of articles, and continuing until adding new search terms produced no more new records recalled. The search strategy thus developed was then tested on the evaluation set of articles. In this case, using the strategy recalled all of the articles which could be obtained using generic search terms; however, adding specific search terms (such as the MeSH term “surgical site infection”) improved recall. Finally, the strategy incorporating both generic and specific search terms for adverse effects was used on the validation set of articles. Search strategies used are included in the article, as is a list in the discussion section of MeSH and Embase indexing terms specific to or suggesting adverse effects. Main Results – “In each case the addition of specific adverse effects terms could have improved the recall of the searches” (p. 127). This was true for all six cases (development, evaluation and validation study sets, for each of MEDLINE and Embase) in which specific terms were added to searches using generic terms, and recall percentages compared. Conclusion – While no filter can deliver 100% of items in a given standard set of studies on adverse effects (since title and abstract fields may not contain any indication of relevance to the topic), adding specific adverse effects terms to generic ones while developing filters is shown to improve recall for surgery-related adverse effects (similarly to drug-related adverse effects). The use of filters requires user engagement and critical analysis; at the same time, deploying well-constructed filters can have many benefits, including: helping users, especially clinicians, get a search started; managing a large and unwieldy set of citations retrieved; and to suggest new search strategies.

955 An Audit for Reviewing the Soft Food Bolus Obstruction - Optimum Intervention and Referral Direction

2021 ◽  
Vol 108 (Supplement_2) ◽  
Author(s):  
N Nargheese ◽  
T Peedika
Keyword(s):  
Patient Satisfaction ◽  
Adverse Effects ◽  
Clinical Governance ◽  
Compelling Evidence ◽  
Food Bolus ◽  
Suprasternal Notch ◽  
Surgical Interventions ◽  
Upper Gi ◽  
Complex Patient

Abstract Introduction Absolute dysphagia secondary to impacted soft food bolus in oesophagus can occur due to various reasons. Existing pathway was ENT if patient points above the suprasternal notch and GI if below or at the level of notch. Objectives To assess management in patients with soft food bolus dysphagia and reviewing old pathway. Method Data was collected via clinical governance, case notes on track and analysed overall pathway of patients and discussed with the consultants; Paid attention to patients requiring surgical interventions, compared the complications 0f OGD and rigidscopy. Also, effectiveness of Buscopan weighing its adverse effects. Results Total of 147 cases were included, 2 patients from upper GI being secondarily referred to ENT, 18 of ENT with GI, 3.8 of 19% complications has risk of perforations with Rigid scope. 2.6% had risk with OGD with no perforations. 2% needed OGD after rigid. 85% underwent intervention after Buscopan. Conclusions There is no compelling evidence for Buscopan - to be used only for patient satisfaction. Combining Multiple transfers & complex patient journeys causing delay for treatments with less complications of OGD, soft food bolus should be managed by local gastro/gen surgery teams who can provide timely appropriate intervention, ENT involvement only if airway or pharyngeal concern.

scholarly journals Nalbuphine Use for Postoperative Pain in Bariatric Surgery: Case Series and Rationale

2020 ◽  
Vol 2 (6) ◽  
Author(s):  
A. R. De Oliveira ◽  
F. S. Conter ◽  
E. S. Martinelli ◽  
A. C. Weston
Keyword(s):  
Bariatric Surgery ◽  
Adverse Effects ◽  
Total Dose ◽  
Case Series ◽  
Laparoscopic Approach ◽  
Relevant Information ◽  
Porto Alegre ◽  
Surgical Interventions ◽  
Significant Difference ◽  
Grade 3

Obesity became an epidemic condition worldwide with a significant impact in healthcare and surgical interventions emerged as a treatment for it. Due to their health conditions, obese population are at higher risk of presenting opioids adverse effects. The goal of this study is to assess the potential use of nalbuphine on bariatric surgery according to its beneficial effect as an agonist-antagonist opioid. A total of 93 medical records of consecutive patients were selected retrospectively at Santa Casa de Porto Alegre Hospital from January 2018 to January 2019. Patients were overall women, middle-aged, with obesity grade 3 and with stable comorbidities. Sleeve gastrectomy was the main surgery technique by laparoscopic approach. Anesthesia used was essentially TIVA, with Dipyrone and NSAIDS as the main adjuvants associated. The time to the first requirement of nalbuphine (TFRN) and total dose of nalbuphine in 24h (TDN24) had medians of 80 minutes and 20mg, respectively. Respiratory depression, urinary retention and pruritus were not found in any patients. The only data statistically significant was sex related TDN24, with men using almost twice larger median doses than women. The analgesic properties and adverse effects profile look encouraging in this setting. The female prevalence is a relevant information considering the influence of gender in nalbuphine efficacy. We can see the agreement with this concept observing that the only statistically significant difference in all study was the total dose of nalbuphine in the first 24h postoperative, favoring females. 

scholarly journals Effectiveness of adverse effects search filters: drugs versus medical devices

2016 ◽  
Vol 104 (3) ◽  
Author(s):  
Kelly Farrah, MLIS, AHIP ◽  
Monika Mierzwinski-Urban, MLIS ◽  
Karen Cimon
Keyword(s):  
Adverse Effects ◽  
Adverse Events ◽  
Medical Devices ◽  
Diagnostic Tests ◽  
Safety Information ◽  
Health Technologies ◽  
Rapid Reviews ◽  
Search Filters ◽  
Testing Set

Objective: The study tested the performance of adverse effects search filters when searching for safety information on medical devices, procedures, and diagnostic tests in MEDLINE and Embase.Methods: The sensitivity of 3 filters was determined using a sample of 631 references from 131 rapid reviews related to the safety of health technologies. The references were divided into 2 sets by type of intervention: drugs and nondrug health technologies. Keyword and indexing analysis were performed on references from the nondrug testing set that 1 or more of the filters did not retrieve.Results: For all 3 filters, sensitivity was lower for nondrug health technologies (ranging from 53%– 87%) than for drugs (88%–93%) in both databases. When tested on the nondrug health technologies set, sensitivity was lower in Embase (ranging from 53%–81%) than in MEDLINE (67%–87%) for all filters. Of the nondrug records that 1 or more of the filters missed, 39% of the missed MEDLINE records and 18% of the missed Embase records did not contain any indexing terms related to adverse events. Analyzing the titles and abstracts of nondrug records that were missed by any 1 filter, the most commonly used keywords related to adverse effects were: risk, complications, mortality, contamination, hemorrhage, and failure.Conclusions: In this study, adverse effects filters were less effective at finding information about the safety of medical devices, procedures, and tests compared to information about the safety of drugs.

scholarly journals Effectiveness of adverse effects search filters: drugs versus medical devices

2016 ◽  
Vol 104 (3) ◽  
pp. 221-225 ◽  
Author(s):  
Kelly Farrah ◽  
Monika Mierzwinski-Urban ◽  
Karen Cimon
Keyword(s):  
Adverse Effects ◽  
Medical Devices ◽  
Search Filters

Evaluation of intestinal microflora composition in patients with burdened allergic history after surgery and its impact on risk of developing antibiotic-associated diarrhea

2020 ◽  
Vol 1 (30) ◽  
pp. 45-47
Author(s):  
M. S. Turchina ◽  
J. E. Annenkova ◽  
M. V. Bukreeva ◽  
L. Yu. Koroleva ◽  
Yu. M. Morozov ◽  
...  
Keyword(s):  
Risk Factors ◽  
Adverse Effects ◽  
Direct Effect ◽  
Broad Spectrum ◽  
Intestinal Microflora ◽  
Adverse Reactions ◽  
Pathological Condition ◽  
Antibacterial Drugs ◽  
Surgical Interventions ◽  
Antibiotic Associated Diarrhea

Currently, patients quite often and often uncontrollably take antibacterial drugs, which leads to the development of various complications from many organs and systems. One of the most common adverse reactions to taking antibiotics is antibiotic-associated diarrhea. Moreover, such a pathological condition is due to both the direct effect of the drug, and a change in the composition of the intestinal microflora. Despite the frequent occurrence of antibiotic-associated diarrhea, this problem raises many questions among practitioners, since the risk factors for its development and methods of prevention have not been fully studied. This is especially important in patients who have undergone surgical interventions, since the combination in this contingent of the appointment of broad-spectrum antibacterial drugs and altered body reactivity in most cases leads to the development of adverse effects.

scholarly journals Searching for Adverse Effects in MEDLINE and EMBASE Requires a Combined Approach for Efficient Retrieval

2006 ◽  
Vol 1 (3) ◽  
pp. 60
Author(s):  
Marcy L. Brown
Keyword(s):  
Systematic Review ◽  
Adverse Effects ◽  
Drug Effects ◽  
Search Strategies ◽  
Controlled Vocabulary ◽  
Medline Search ◽  
Drug Names ◽  
Final Approach ◽  
Search Filters ◽  
The Uk

A review of: Golder, Su, Heather M. McIntosh, Steve Duffy, and Julie Glanville. “Developing Efficient Search Strategies to Identify Reports of Adverse Effects in MEDLINE and EMBASE.” Health Information & Libraries Journal 23.1 (Mar. 2006): 3-12. Objective – To assess the sensitivity and precision of various search strategies for retrieving adverse effects studies from the MEDLINE and EMBASE databases. Design – Analytical survey. Subjects – A case study using a recently published systematic review of the effectiveness and adverse effects of seven new anti-epileptic drugs. Setting – MEDLINE and EMBASE searches performed by researchers at the Centre for Reviews and Dissemination and the UK Cochrane Centre Search Filters Design Group at the University of York, UK. Methods – Five key approaches to searching were defined. The first approach used either text words or controlled vocabulary to search for specific adverse effects. The second used subheadings or qualifiers either attached to drug names found in the controlled vocabulary (approach 2a) or ‘floating’ without drug names (approach 2b). The third approach used text words as synonyms for the phrase ‘adverse effects.’ The fourth used controlled indexing terms for adverse effects. The fifth and final approach used two published search strategies incorporating study design (Badgett et al., Loke et al.). These five approaches were used to search for studies of the adverse effects of seven new anti-epileptic drugs. 5,011 unique papers were retrieved. Of these, 236 were judged potentially relevant and 225 full text articles were obtained. The inclusion criteria from a previously published systematic review (Wilby et al.) were applied to the papers, and 79 met the criteria. Five papers were added to the set after being identified from reference lists, clinical experts, and other sources. This new set of 84 studies was used as a quasi gold standard (QGS) against which more than 300 combinations of the five approaches could be tested. To create the set of possible approaches, the researchers combined search strategies one through four in all possible ways, and used all available subheading combinations from 2a and 2b. The Badgett and Loke searches were tested separately. Main Results – Sensitivity and precision were determined for each combination. Formulas used to calculate sensitivity and precision were provided. In MEDLINE, search strategies using floating subheadings achieved the highest sensitivity. The most useful single subheading in both MEDLINE and EMBASE was “adverse effects,” with 79.1% and 79.5% sensitivity respectively. Of the more than 300 combinations tested, the most sensitive combination in MEDLINE included specified adverse effects in combination with the floating subheadings “adverse effects,” “complications,” and “drug effects,” together with text words for adverse effects. This strategy had 97.0% sensitivity, but low precision at 2.8%. The highest precision was achieved by using subheadings attached to drug indexing terms. In EMBASE, the strategy of Loke et al. provided the highest sensitivity at 86.3% and precision of 2.0%. Since researchers are not likely to know in advance all of the reported adverse effects of a particular drug therapy, the most sensitive strategies without specific adverse events were also identified. The search with the highest sensitivity in MEDLINE had 95.5% sensitivity, and 97.3% sensitivity in EMBASE. Conclusion – Searching for adverse effects requires a combination of approaches in both MEDLINE and EMBASE. In MEDLINE, the most sensitive combination yielded 97.0% sensitivity. Regardless of the approach used, precision remains low. An effective generic search filter for adverse effects searches may not yet be feasible. More research is needed on search strategies, as well as more consistent methods of reporting and indexing adverse effects.

scholarly journals Diverse approaches to scoliosis in young children

2020 ◽  
Vol 5 (10) ◽  
pp. 753-762 ◽  
Author(s):  
Alpaslan Senkoylu ◽  
Rolf B. Riise ◽  
Emre Acaroglu ◽  
Ilkka Helenius
Keyword(s):  
Young Children ◽  
Adverse Effects ◽  
Vertebral Body ◽  
Early Onset ◽  
Long Term Results ◽  
Spine Deformity ◽  
Surgical Interventions ◽  
Growing Rods ◽  
Serial Casting ◽  
Magnetically Controlled Growing Rods

Management of scoliosis in young children needs a comprehensive approach because of its complexity. There are many debatable points; however, only serial casting, growing rods (including traditional and magnetically controlled) and anterior vertebral body tethering will be discussed in this article. Serial casting is a time-gaining method for postponing surgical interventions in early onset scoliosis, despite the fact that it has some adverse effects which should be considered and discussed with the family beforehand. Use of growing rods is a growth-friendly surgical technique for the treatment of early onset spine deformity which allows chest growth and lung development. Magnetically controlled growing rods are effective in selected cases although they sometimes have a high number of unplanned revisions. Anterior vertebral body tethering seems to be a promising novel technique for the treatment of idiopathic scoliosis in immature cases. It provides substantial correction and continuous curve control while maintaining mobility between spinal segments. However, long-term results, adverse effects and their prevention should be clarified by future studies. Cite this article: EFORT Open Rev 2020;5:753-762. DOI: 10.1302/2058-5241.5.190087

scholarly journals Analysis of Commission Forensic-medical Examinations performed in Cases Concerning the Responsibility of Surgical Professional Doctors

2020 ◽  
Vol 27 (2) ◽  
pp. E2020210
Author(s):  
Natalia Kozan ◽  
Volodymyr Voloshynovych ◽  
Yuliia Kotsyubynska ◽  
Halyna Zelenchuk ◽  
Andrii Tsikhivskyi
Keyword(s):  
Adverse Effects ◽  
Annual Reports ◽  
Criminal Case ◽  
Medical Professionals ◽  
Surgical Interventions ◽  
Medical Expertise ◽  
Legal Literacy ◽  
Examination Methods ◽  
Medical Examinations ◽  
Therapeutic Profile

The objective of the research was the analysis of the structure of the commission of forensic medical examinations concerning professional offenses of medical professionals of the surgical profile according to the data of the Ivano-Frankivsk Regional Bureau of Forensic Medical Expertise for the period 2015-2019. Materials and methods. The material of the study were the annual reports of the Ivano-Frankivsk Regional Bureau of Forensic Medical Expertise (Commission Department) and criminal case materials. Obtained data were processed using Microsoft Exel, Statistica 6.0.  Results. It was found that forensic medical examinations in case of improper performance of professional duties by medical workers accounted for a relatively small part 71 (14.3%) of the total forensic medical expertise. After the performed analysis, it was found that the doctors made diagnostic, therapeutic, organizational-tactical, deontological and combined errors that had a direct (29%) or indirect (26%) connection with the onset of death or adverse effects on the patient’s health. In 45% of cases, there was no correlation between the doctor’s actions and the occurrence of adverse effects for the patient. Conclusions. The number of cases for improper performance of professional duties by medical workers is significantly higher in surgeons and obstetricians-gynecologists than in doctors of therapeutic profile. Every year, the complexity of commission forensic medical examinations in case of improper performance of professional duties by medical workers increases. This is due to the increasing complexity of surgical interventions and instrumental examination methods, as well as the increasing legal literacy of the population.

scholarly journals The development of search filters for adverse effects of medical devices in medline and embase

2019 ◽  
Vol 36 (3) ◽  
pp. 244-263 ◽  
Author(s):  
Su Golder ◽  
Kelly Farrah ◽  
Monika Mierzwinski‐Urban ◽  
Kath Wright ◽  
Yoon Kong Loke
Keyword(s):  
Adverse Effects ◽  
Medical Devices ◽  
Search Filters
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