Favorable outcomes of surgical resection for extrahepatic recurrent hepatocellular carcinoma

2020 ◽  
Author(s):  
Yutaka Midorikawa ◽  
Tadatoshi Takayama ◽  
Hisashi Nakayama ◽  
Masamichi Moriguchi ◽  
Osamu Aramaki ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Surgical Resection ◽  
Recurrent Hepatocellular Carcinoma

Surgical resection for recurrent hepatocellular carcinoma: Prognosis and analysis of risk factors

Surgery ◽  
1996 ◽  
Vol 120 (1) ◽  
pp. 23-29 ◽  
Author(s):  
Rey-Heng Hu ◽  
Po-Huang Lee ◽  
Sen-Chang Yu ◽  
Hao-Che Dai ◽  
Jin-Chuan Sheu ◽  
...  
Keyword(s):  
Risk Factors ◽  
Hepatocellular Carcinoma ◽  
Surgical Resection ◽  
Recurrent Hepatocellular Carcinoma

scholarly journals Comparison of repeated surgical resection and radiofrequency ablation for small recurrent hepatocellular carcinoma after primary resection

Oncotarget ◽  
2017 ◽  
Vol 8 (61) ◽  
pp. 104571-104581 ◽  
Author(s):  
Wei-Chi Sun ◽  
I-Shu Chen ◽  
Huei-Lung Liang ◽  
Cheng-Chung Tsai ◽  
Yu-Chia Chen ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Radiofrequency Ablation ◽  
Surgical Resection ◽  
Primary Resection ◽  
Recurrent Hepatocellular Carcinoma

PIVKA-II Is a Useful Tumor Marker for Recurrent Hepatocellular Carcinoma after Surgical Resection

Oncology ◽  
2007 ◽  
Vol 72 (1) ◽  
pp. 52-57 ◽  
Author(s):  
Do Young Kim ◽  
Yong Han Paik ◽  
Sang Hoon Ahn ◽  
Young Jun Youn ◽  
Jong Won Choi ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Tumor Marker ◽  
Surgical Resection ◽  
Recurrent Hepatocellular Carcinoma

Surgical Resection versus Re-Ablation for Intrahepatic Recurrent Hepatocellular Carcinoma after Initial Ablation Therapy

2020 ◽  
pp. 1-12
Author(s):  
Yongjin Wang ◽  
Yadi Liao ◽  
Wenwu Liu ◽  
Yuanping Zhang ◽  
Yichuan Yuan ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Surgical Resection ◽  
Proportional Hazards Model ◽  
Disease Free Survival ◽  
Cox Proportional Hazards ◽  
Cox Proportional Hazards Model ◽  
Significant Prognostic Factor ◽  
Curative Intent ◽  
Resection Group ◽  
Recurrent Hepatocellular Carcinoma

<b><i>Background and Aims:</i></b> Whether surgical resection or repeated ablation should be recommended for intrahepatic recurrent hepatocellular carcinoma (HCC) conforming to the Milan criteria after initial ablation remains unclear. In this study, we compared the outcomes of patients who underwent surgical resection with those who underwent re-ablation for recurrent HCC after initial curative-intent ablation. <b><i>Methods:</i></b> The data of 28 and 98 patients who underwent surgical resection and re-ablation, respectively, for recurrent HCC after initial ablation between January 2003 and 2017 were analyzed using propensity score matching. <b><i>Results:</i></b> Before matching, the 1-, 3-, and 5-year overall survival (OS) rates were 95.7, 83.0, and 74.4% for the ablation group, compared to 92.9, 89.1, and 70.9% for the resection group (<i>p</i> = 0.490). The corresponding disease-free survival (DFS) rates were 67.5, 40.1, and 25.6% for the ablation group and were 85.4, 59.9, and 53.3% for the resection group (<i>p</i> = 0.018). After matching, the 1-, 3-, and 5-year OS rates for the ablation and resection group were 95.2, 85.5 and 81.8% versus 96.0, 96.0, and 76.4%, respectively (<i>p</i> = 0.550). The 1-, 3-, and 5-year DFS rates were 58.0, 39.5, and 29.9% for the ablation group and were 95.8, 67.2, and 59.8% for the resection group (<i>p</i> = 0.004). Cox proportional hazards model identified surgical resection as the only significant prognostic factor for DFS but not for OS. <b><i>Conclusion:</i></b> For intrahepatic recurrent HCC patients after initial ablation, surgical resection could provide better DFS than re-ablation, while no difference in OS was observed between the 2 treatment groups.

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