scholarly journals Compartment model analysis of intravenous contrast-enhanced dynamic computed tomography in hepatic hemodynamics: A validation study using intra-arterial contrast-enhanced computed tomography

2018 ◽  
Vol 48 (10) ◽  
pp. 829-838 ◽  
Author(s):  
Daisuke Komatsu ◽  
Akira Yamada ◽  
Takeshi Suzuki ◽  
Masahiro Kurozumi ◽  
Yasunari Fujinaga ◽  
...  
2020 ◽  
pp. 102490792091339
Author(s):  
Seda Dağar ◽  
Emine Emektar ◽  
Hüseyin Uzunosmanoğlu ◽  
Şeref Kerem Çorbacıoğlu ◽  
Özge Öztekin ◽  
...  

Background: Despite its risks associated with renal injury, intravenous contrast media increases diagnostic efficacy and hence the chance of early diagnosis and treatment, which leaves clinicians in a dilemma regarding its use in emergency settings. Objective: The aim of this study was to determine the risk and predictors of contrast-induced acute kidney injury following intravenous contrast media administration for computed tomography in the emergency department. Methods: All patients aged 18 years and older who had a basal creatinine measurement within the last 8 h before contrast-enhanced computed tomography and a second creatinine measurement within 48–72 h after computed tomography scan between 1 January 2015 and 31 December 2017 were included in the study. Characteristics of patients with and without contrast-induced acute kidney injury development were compared. Multivariate regression analysis was used to assess the predictors for contrast-induced acute kidney injury. Results: A total of 631 patients were included in the final statistical analysis. After contrast media administration, contrast-induced acute kidney injury developed in 4.9% ( n = 31) of the patients. When the characteristics of patients are compared according to the development of contrast-induced acute kidney injury, significant differences were detected for age, initial creatinine, initial estimated glomerular filtration rate, and all acute illness severity indicators (hypotension, anemia, hypoalbuminemia, and need for intensive care unit admission). A multivariate logistic regression analysis was performed. The need for intensive care unit admission (odds ratio: 6.413 (95% confidence interval: 1.709–24.074)) and hypotension (odds ratio: 5.575 (95% confidence interval: 1.624–19.133)) were the main factors for contrast-induced acute kidney injury development. Conclusion: Our study results revealed that hypotension, need for intensive care, and advanced age were associated with acute kidney injury in patients receiving contrast media. Therefore, we believe that to perform contrast-enhanced computed tomography in emergency department should not be decided only by checking for renal function tests and that these predictors should be taken into consideration.


PLoS ONE ◽  
2019 ◽  
Vol 14 (7) ◽  
pp. e0219605 ◽  
Author(s):  
Kai Jiang ◽  
Christopher M. Ferguson ◽  
Abdelrhman Abumoawad ◽  
Ahmed Saad ◽  
Stephen C. Textor ◽  
...  

2013 ◽  
pp. 71-75
Author(s):  
Vi Thang Huynh ◽  
Trong Khoan Le ◽  
Trong Hao Vo

Objectives: To assess morphologic features, signal characteristics on sonography and dynamic computed tomography of hepatic hemangiomas. To compare the agreement degree of diagnosis of hepatic hemangiomas between sonography and computed tomography. Material and methods: We researched the sonography and computed tomography findings in 50 patients including 82 lesions hepatic hemangiomas at Hue university hospital and Hue central hospital from march 2012 to june 2013, 21 men and 29 women, mean age 51.7 ± 13.9 (range 30 – 89). Results: Mean mass diameter was 3.7 ± 1.9 cm. Sonography revealed hyperechonic pattern in 97.6% and hypoechonic pattern in 2.4%. On nonenhanced computed tomography, almost tumors (70.8%) showed hypodense, 26.8% had cleftlike areas of lower density than the main mass and 2.4% showed hyperdense lesions in a hypodense fatty liver. Almost tumors were periperally hyperdense on early contrast - enhanced computed tomography, progressive centripetal enhancement and in the delayed phase 85.4% displayed isodense and 14.6% displayed hyperdense fill-in. Conclusions: Triphasic helical computed tomography has additional values for sonography in diagnosis of hepatic hemangioma with typical characteristics: hypodense lesion on nonenhanced computed tomography, periperally hyperdense on early contrast - enhanced computed tomography, progressive centripetal enhancement and complete isodense fill-in of the lesion in the delayed phase. For tiny lesion smaller than 15mm (especially smaller than 10 mm), computed tomography plays a less important role. Key words: Hepatic hemangiomas, signal characteristics, sonography, computed tomography, research.


2021 ◽  
Vol 52 (2) ◽  
Author(s):  
Kelsey Brust ◽  
Kathryn Phillips ◽  
Mary Kaufman ◽  
Brittany Stevens ◽  
Alvin Camus ◽  
...  

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