Relative changes in handgrip strength and skeletal muscle volume in patients with chronic liver disease over a 2-year observation period

2018 ◽  
Vol 48 (7) ◽  
pp. 502-508 ◽  
Author(s):  
Atsushi Hiraoka ◽  
Kojiro Michitaka ◽  
Hirofumi Izumoto ◽  
Hidetaro Ueki ◽  
Shogo Kitahata ◽  
...  
2018 ◽  
Vol 33 (9) ◽  
pp. 1659-1666 ◽  
Author(s):  
Yoshihiko Tachi ◽  
Akihiro Kozuka ◽  
Takanori Hirai ◽  
Yoji Ishizu ◽  
Takashi Honda ◽  
...  

2019 ◽  
Vol 10 (2) ◽  
pp. 347-354 ◽  
Author(s):  
Atsushi Hiraoka ◽  
Hirofumi Izumoto ◽  
Hidetaro Ueki ◽  
Takeaki Yoshino ◽  
Toshihiko Aibiki ◽  
...  

2021 ◽  
Vol 2021 ◽  
pp. 1-7
Author(s):  
Giovanni Marasco ◽  
Sinan Sadalla ◽  
Giulio Vara ◽  
Rita Golfieri ◽  
Davide Festi ◽  
...  

Sarcopenia is gaining attention as a negative prognostic factor in different fields of medicine, including chronic liver failure. However, the assessment of sarcopenia in patients with liver diseases is often neglected due to unawareness of reliable tools and methods and thus is limited to research studies. Cross-sectional imaging is a diffuse diagnostic tool and is commonly performed in patients with chronic liver failure. The last advancements in radiology image analysis using dedicated software allow an easy and standardized method to assess skeletal muscle volume. Several measures can be obtained from cross-sectional imaging analysis to evaluate sarcopenia in patients affected by chronic liver disease. We aimed to review the recent advances in imaging-based sarcopenia assessment, in particular in patients with chronic liver diseases. As a result, we found that the skeletal muscle index (SMI) seems to be a reliable method to assess sarcopenia in cirrhotic patients. Even if further studies are needed to validate proper cut-offs for each clinical endpoint, physicians are invited to consider the assessment of sarcopenia in the work-up of patients with chronic liver disease.


2019 ◽  
Vol 70 (1) ◽  
pp. e684
Author(s):  
Tomoyuki Suehiro ◽  
Yuki Kugiyama ◽  
Shigemune Bekki ◽  
Satoru Hashimoto ◽  
Akira Saeki ◽  
...  

2020 ◽  
Vol 50 (6) ◽  
pp. 704-714
Author(s):  
Tatsuki Ichikawa ◽  
Hisamitsu Miyaaki ◽  
Satoshi Miuma ◽  
Yasuhide Motoyoshi ◽  
Mio Yamashima ◽  
...  

Nutrition ◽  
2018 ◽  
Vol 54 ◽  
pp. 83-88 ◽  
Author(s):  
Yoshihiko Tachi ◽  
Akihiro Kozuka ◽  
Takanori Hirai ◽  
Yuko Kojima ◽  
Yoji Ishizu ◽  
...  

2017 ◽  
Vol 47 (12) ◽  
pp. 1223-1234 ◽  
Author(s):  
Hiroki Nishikawa ◽  
Hirayuki Enomoto ◽  
Akio Ishii ◽  
Yoshinori Iwata ◽  
Yuho Miyamoto ◽  
...  

2016 ◽  
Vol 64 (2) ◽  
pp. S284-S285
Author(s):  
S.E. Brown ◽  
Z. Mrevlje ◽  
N. Vidas ◽  
P.A. Kane ◽  
N. Heaton ◽  
...  

2019 ◽  
Vol 49 (12) ◽  
pp. 1427-1440 ◽  
Author(s):  
Ayu Nagamatsu ◽  
Takumi Kawaguchi ◽  
Keisuke Hirota ◽  
Shunji Koya ◽  
Manabu Tomita ◽  
...  

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Tongzeng Li ◽  
Manman Xu ◽  
Ming Kong ◽  
Wenyan Song ◽  
Zhongping Duan ◽  
...  

AbstractSarcopenia is a well-recognized factor affecting the prognosis of chronic liver disease, but its impact on acute decompensation underlying chronic liver disease is unknown. This study evaluated the impact of sarcopenia on short-term mortality in patients with acute-on-chronic liver failure (ACLF). One hundred and seventy-one ACLF patients who underwent abdominal CT between 2015 and 2019 were retrospectively included in this study. Skeletal muscle index at the third lumbar vertebrae (L3-SMI) was used to diagnose sarcopenia.The ACLF patients in this study had a L3-SMI of 41.2 ± 8.3 cm2/m2 and sarcopenia was present in 95/171 (55.6%) patients. Body mass index (BMI), cirrhosis, and higher serum bilirubin were independently associated with sarcopenia. Following multivariate Cox regression analysis, cirrhosis (hazard ratio (HR) 2.758, 95%CI 1.323–5.750), serum bilirubin (HR 1.049, 95%CI 1.026–1.073), and international normalized ratio (INR) (HR 1.725, 95%CI 1.263–2.355) were associated with 3-month mortality (P < 0.05), whereas L3-SMI and sarcopenia were not. A subgroup analysis of the factors related to sarcopenia showed that sarcopenia was still not predictive of short-term outcome in ACLF patients. L3-SMI and sarcopenia are not associated with short-term mortality in patients with ACLF.


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