Helicobacter pylori “Test‐and‐Treat” strategy with urea breath test: A cost‐effective strategy for the management of dyspepsia and the prevention of ulcer and gastric cancer in Spain—Results of the Hp‐Breath initiative

Helicobacter ◽  
2020 ◽  
Vol 25 (4) ◽  
Author(s):  
Ariel Beresniak ◽  
Peter Malfertheiner ◽  
Francesco Franceschi ◽  
Francois Liebaert ◽  
Hocine Salhi ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Helicobacter Pylori ◽  
Breath Test ◽  
Cost Effective ◽  
Urea Breath Test ◽  
Effective Strategy ◽  
Test And Treat ◽  
Cost Effective Strategy

Cost-effectiveness analysis of Helicobacter pylori screening in prevention of gastric cancer in Chinese

2008 ◽  
Vol 24 (01) ◽  
pp. 87-95 ◽  
Author(s):  
Feng Xie ◽  
Nan Luo ◽  
Gord Blackhouse ◽  
Ron Goeree ◽  
Hin-Peng Lee
Keyword(s):  
Gastric Cancer ◽  
Helicobacter Pylori ◽  
Cost Effectiveness ◽  
Model Simulation ◽  
Healthcare Providers ◽  
Cost Effective ◽  
Public Healthcare ◽  
Effective Strategy ◽  
Cost Effective Strategy ◽  
Life Years

Objectives:The aim of this study was to evaluate the costs and effectiveness associated with no screening,Helicobacter pyloriserology screening, and the13C-urea breath test (UBT) for gastric cancer in the Chinese population.Methods:A Markov model simulation was carried out in Singaporean Chinese at 40 years of age (n= 478,500) from the perspective of public healthcare providers. The main outcome measures were costs, number of gastric cancer cases prevented, life-years saved, quality-adjusted life-years (QALYs) gained from the screening age to death, and incremental cost-effectiveness ratios (ICERs), which were compared among the three strategies. The uncertainty surrounding ICERs was addressed by scenario analyses and probabilistic sensitivity analysis using Monte Carlo simulation.Results: The ICER of serology screening versus no screening was $25,881 per QALY gained (95 percent confidence interval (95 percent CI), $5,700 to $120,000). The ICER of UBT versus no screening was $53,602 per QALY gained (95 percent CI, $16,000 to $230,000). ICER of UBT versus serology screening was $470,000 per QALY gained, for which almost all random samples of the ICERs distributed above $50,000 per QALY.Conclusions: It cannot be confidently concluded that eitherH pyloriscreening was a cost-effective strategy compared with no screening in all Chinese at the age of 40 years. Nevertheless, serology screening has demonstrated much more potential to be a cost-effective strategy, especially in the population with higher gastric cancer prevalence.

A comparative study of the 14C-Urea Breath Test and histology for the detection of Helicobacter pylori in terms of cost effectiveness and patient acceptability

2001 ◽  
Author(s):  
◽  
Fawzia Ismail Peer
Keyword(s):  
Helicobacter Pylori ◽  
Cost Effectiveness ◽  
Biopsy Specimen ◽  
Breath Test ◽  
Histological Analysis ◽  
Cost Effective ◽  
Urea Breath Test ◽  
Patient Acceptability ◽  
Carbon 14 ◽  
H Pylori

The purpose of this study was to evaluate the Carbon-14 Urea Breath Test e4C-UBT) and histology for the detection of Helicobacter pylori (H pylori) in terms of cost-effectiveness and patient perceptions. It was hypothesized that the 14C_UBTwas more cost-effective and more easily tolerated than a histological analysis of a biopsy specimen obtained on endoscopy for H pylori detection

scholarly journals Association of Helicobacter Pylori Infection in Patients Having Coronary Artery Disease

2004 ◽  
Vol 3 (3) ◽  
pp. 7
Author(s):  
A Ranjit ◽  
CM Pathak ◽  
K.L. Khanduja ◽  
H.K. Ball ◽  
D.K. Bhasin
Keyword(s):  
Gastric Cancer ◽  
Coronary Artery Disease ◽  
Coronary Heart Disease ◽  
Helicobacter Pylori ◽  
Gastric Ulcer ◽  
Coronary Artery ◽  
Breath Test ◽  
Urea Breath Test ◽  
Artery Disease ◽  
H Pylori

Helicobacter pylori usually cause a lifelong infection of gastric mucosa that may lead to gastric ulcer and later on gastric cancer. H, pylori infection and coronary heart disease are common conditions in late middle and old age. Recently, some studies have found casual association between H. Pylori infection and coronary artery disease, cerebrovascular disease and atherosclerosis. The study was done to detect the presence of H. Pylori in patients of coronary artery disease (CAD) by 14C-urea breath test and to find out any possible association between H. Pylori infection and coronary artery disease,

Prevalence of Helicobacter Pylori in gastric cancer in a South-east Asian Population by 14 C-Urea breath test

2001 ◽  
Vol 71 (10) ◽  
pp. 574-576 ◽  
Author(s):  
Alexander Y-F. Chung ◽  
Pierce K. H. Chow ◽  
Wing-Kwong Yu ◽  
Jean M. S. Ho ◽  
Hsiang-Sui Chan ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Helicobacter Pylori ◽  
Breath Test ◽  
East Asian ◽  
Asian Population ◽  
Urea Breath Test ◽  
East Asian Population
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