Intravenous Magnesium Sulfate to Treat Acute Headaches in the Emergency Department: A Systematic Review

2019 ◽  
Vol 59 (10) ◽  
pp. 1674-1686 ◽  
Author(s):  
Andrew C. Miller ◽  
Brandon K. Pfeffer ◽  
Michael R. Lawson ◽  
Kerry A. Sewell ◽  
Alexandra R. King ◽  
...  
Keyword(s):  
Systematic Review ◽  
Emergency Department ◽  
Magnesium Sulfate ◽  
Intravenous Magnesium

Intravenous Magnesium Sulfate Treatment for Acute Asthma in the Emergency Department: A Systematic Review of the Literature

2000 ◽  
Vol 36 (3) ◽  
pp. 181-190 ◽  
Author(s):  
Brian H. Rowe ◽  
Jennifer A. Bretzlaff ◽  
Chris Bourdon ◽  
Gary W. Bota ◽  
Carlos A. Camargo
Keyword(s):  
Systematic Review ◽  
Emergency Department ◽  
Magnesium Sulfate ◽  
Acute Asthma ◽  
Review Of The Literature ◽  
Intravenous Magnesium

scholarly journals The Effect of Intravenous Magnesium Sulphate as an Adjuvant in the Treatment of Acute Exacerbations of COPD in the Emergency Department: A Double-Blind Randomized Clinical Trial

2021 ◽  
Vol 31 (2) ◽  
Author(s):  
Fatemeh Jahanian ◽  
Iraj Goli Khatir ◽  
Hamed Amini Ahidashti ◽  
Sepideh Amirifard
Keyword(s):  
Clinical Trial ◽  
Emergency Department ◽  
Magnesium Sulfate ◽  
Magnesium Sulphate ◽  
Intervention Group ◽  
Control Group ◽  
Double Blind ◽  
Intravenous Magnesium ◽  
Acute Exacerbations ◽  
And Control

BACKGROUND፡ Acute exacerbations of chronic obstructive pulmonary disease (AECOPD) are serious complications that often require immediate intervention in an emergency department (ED). The aim of this study was to investigate the effect of intravenous magnesium sulphate as an adjuvant in the treatment of AECOPD in the ED.METHODS: In a double-blind, randomized clinical trial, a total of 60 patients with AECOPD presenting to the ED of Imam Khomeini Hospital in Sari, Iran, were included. The study was conducted between September 2016 and February 2018. Eligible patients were randomly allocated into two groups of intervention and control. Patients in the intervention and control groups received intravenous infusion of magnesium sulfate (2 gr) or normal saline over 30 minutes, respectively. For all patients, Borgdyspnea score, forced expiratory volume in one second (FEV1) result and clinical variables of interest were evaluated before the beginning of the intervention, and also 45 minutes and 6 hours after the commencement of intervention.RESULTS: Regardless of time of evaluation, pulse rate (PR), respiratory rate (RR) and Borg score in intervention group was lower than control group. Also, FEV1 and SPO2 were greater in intervention group compared to control group. However, these differences were not statistically significant (between-subject differences or group effect) (p<0.001). The trends of FEV1, SPO2, PR, RR and Borg score were similar between two groups of study (no interaction effect; P>0.05).CONCLUSION: According to the results of this study, it seems that using intravenous magnesium sulfate has no significant effect on SPO2, FEV1, RR, and PR of patients with AECOPD who presented to ED.

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