scholarly journals Chronic Migraine Is Associated With Reduced Corneal Nerve Fiber Density and Symptoms of Dry Eye

2015 ◽  
Vol 55 (4) ◽  
pp. 543-549 ◽  
Author(s):  
Krista I. Kinard ◽  
A. Gordon Smith ◽  
J. Robinson Singleton ◽  
Margaret K. Lessard ◽  
Bradley J. Katz ◽  
...  
Keyword(s):  
Chronic Migraine ◽  
Nerve Fiber ◽  
Dry Eye ◽  
Fiber Density ◽  
Corneal Nerve ◽  
Nerve Fiber Density

scholarly journals Erratum to: ARA 290 Improves Symptoms in Patients with Sarcoidosis-Associated Small Nerve Fiber Loss and Increases Corneal Nerve Fiber Density

2016 ◽  
Vol 22 (1) ◽  
pp. 674-674
Author(s):  
Albert Dahan ◽  
Ann Dunne ◽  
Maarten Swartjes ◽  
Paolo L. Proto ◽  
Lara Heij ◽  
...  
Keyword(s):  
Nerve Fiber ◽  
Fiber Density ◽  
Corneal Nerve ◽  
Nerve Fiber Density ◽  
Small Nerve

scholarly journals Reduced Corneal Nerve Fiber Density in Type 2 Diabetes by Wide-Area Mosaic Analysis

2017 ◽  
Vol 58 (14) ◽  
pp. 6318 ◽  
Author(s):  
Neil S. Lagali ◽  
Stephan Allgeier ◽  
Pedro Guimarães ◽  
Reza A. Badian ◽  
Alfredo Ruggeri ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Nerve Fiber ◽  
Wide Area ◽  
Fiber Density ◽  
Mosaic Analysis ◽  
Corneal Nerve ◽  
Nerve Fiber Density

scholarly journals ARA 290 Improves Symptoms in Patients with Sarcoidosis-Associated Small Nerve Fiber Loss and Increases Corneal Nerve Fiber Density

2013 ◽  
Vol 19 (1) ◽  
pp. 334-345 ◽  
Author(s):  
Albert Dahan ◽  
Ann Dunne ◽  
Maarten Swartjes ◽  
Paolo L. Proto ◽  
Lara Heij ◽  
...  
Keyword(s):  
Nerve Fiber ◽  
Fiber Density ◽  
Corneal Nerve ◽  
Nerve Fiber Density ◽  
Small Nerve

scholarly journals Assessment and comparison of the morphology and function of the corneal sub-basal nerve plexus in type-1 diabetes mellitus patients and in healthy subjects

2016 ◽  
Vol 1 (1) ◽  
pp. 51-63
Author(s):  
Irmante Derkac ◽  
Ingrida Januleviciene ◽  
Kirwan Asselineau ◽  
Dzilda Velickiene
Keyword(s):  
Nerve Fiber ◽  
Healthy Subjects ◽  
Nerve Fibers ◽  
Corneal Sensitivity ◽  
Fiber Density ◽  
Corneal Confocal Microscopy ◽  
Corneal Nerve ◽  
Type 1 Dm ◽  
Nerve Fiber Density

Aim/purpose: It is believed that small nerve bundles are damaged in the earliest stages of neuropathy caused by diabetes mellitus (DM). Our goal was to evaluate and compare anatomical characteristics of corneal nerve fibers and corneal sensitivity in type-1 DM patients and in healthy control subjects.Design: A prospective, masked, controlled cross-sectional clinical study.Method: Thirty patients with type-1 DM and ten non-diabetic healthy subjects underwent a corneal confocal microscopy to evaluate the corneal sub-basal nerve fibers (density, number of nerves and branches, total nerve length) and contact corneal esthesiometry.Results: Diabetic patients had significantly lower corneal nerve fiber density density (14.32 ± 5.87 vs. 19.71 ± 5.59 mm/mm2; p = 0.023 ) nerve branches number (4.57 ± 3,91 vs. 9.90 ± 5.8 n°/image; p = 0.006) , nerve fiber length (2.28 ± 0.94 vs. 3.13 ± 0.89 mm; p = 0.032) and corneal sensitivity (1.13 ± 0.29 vs. 0.98 ± 0.058 gr/mm2 p = 0.02), as compared with controls. A negative correlation was found between corneal nerve fiber length, corneal nerve number, corneal nerve fiber density and disease duration (p < 0.05).Conclusion: Corneal confocal microscopy and corneal sensitivity evaluation are noninvasive techniques helping to detect early changes in the sub-basal nerve plexus characteristic for diabetic neuropathy (DN) in patients with type-1 DM. Further studies are required to investigate the role of corneal neuropathy assessment using these novel techniques as a toll to detect early DN. 

scholarly journals Intraepidermal Nerve Fiber Density in Friedreich’s Ataxia

2018 ◽  
Vol 77 (12) ◽  
pp. 1137-1143 ◽  
Author(s):  
Elisabetta Indelicato ◽  
Wolfgang Nachbauer ◽  
Andreas Eigentler ◽  
Dagmar Rudzki ◽  
Julia Wanschitz ◽  
...  
Keyword(s):  
Nerve Fiber ◽  
Friedreich’S Ataxia ◽  
Friedreich's Ataxia ◽  
Fiber Density ◽  
Intraepidermal Nerve Fiber Density ◽  
Nerve Fiber Density ◽  
Intraepidermal Nerve Fiber

scholarly journals Epidermal nerve fiber density, oxidative stress, and mitochondrial haplogroups in HIV-infected Thais initiating therapy

AIDS ◽  
2014 ◽  
Vol 28 (11) ◽  
pp. 1625-1633 ◽  
Author(s):  
Todd Hulgan ◽  
Rebecca T. Levinson ◽  
Mariana Gerschenson ◽  
Nittaya Phanuphak ◽  
Jintanat Ananworanich ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Nerve Fiber ◽  
Mitochondrial Haplogroups ◽  
Fiber Density ◽  
Epidermal Nerve Fiber Density ◽  
Nerve Fiber Density ◽  
Epidermal Nerve Fiber
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