Continuous venovenous hemodialysis may be effective in digoxin removal in digoxin toxicity: A case report

2020 ◽  
Vol 24 (4) ◽  
Author(s):  
Cenk Gokalp ◽  
Aysun Fatma Dogan ◽  
Guray Aygun ◽  
Ilhan Kurultak ◽  
Sedat Ustundag
Keyword(s):  
Case Report ◽  
Digoxin Toxicity ◽  
Continuous Venovenous Hemodialysis

scholarly journals PP017—Spectrum of ocular digoxin toxicity in the elderly: A case report

2013 ◽  
Vol 35 (8) ◽  
pp. e22-e23 ◽  
Author(s):  
D. Renard ◽  
E. Rubli ◽  
N. Voide ◽  
F.-X. Borruat ◽  
L. Rothuizen
Keyword(s):  
Case Report ◽  
The Elderly ◽  
Digoxin Toxicity

scholarly journals Digoxin Toxicity in a Patient with Pacemaker: A Case Report

Cureus ◽  
2019 ◽  
Author(s):  
Rachel E Bridwell ◽  
Keith A Baker ◽  
Christopher O Hoyte ◽  
Patrick C Ng
Keyword(s):  
Case Report ◽  
Digoxin Toxicity

Life-threatening digoxin toxicity due to drug–drug interactions in an HIV-positive man

2016 ◽  
Vol 28 (3) ◽  
pp. 297-301 ◽  
Author(s):  
Kathir Yoganathan ◽  
Beth Roberts ◽  
Martyn K Heatley
Keyword(s):  
Drug Interaction ◽  
Case Report ◽  
Drug Interactions ◽  
Digoxin Toxicity ◽  
Hiv Positive ◽  
Hiv Patients ◽  
First Case ◽  
Life Threatening ◽  
Drug Drug Interaction ◽  
Positive Population

Drug–drug interactions with corticosteroids, causing Cushing’s syndrome with secondary adrenal suppression, are well known in HIV patients. Corticosteroids are widely prescribed in the HIV-positive population. However, digoxin is rarely used in HIV patients; hence, digoxin toxicity due to drug–drug interaction is not widely recognised. Nevertheless, this practice might change in the future as HIV cohorts of patients are ageing, due to the successful treatment of HIV infection with combination antiretroviral therapy. We report a case of digoxin toxicity in an HIV-positive 51-year-old man, due to a combination of drug–drug interaction and renal impairment. The first case report of digoxin toxicity due to drug–drug interaction with ritonavir in an HIV-positive woman was published in 2003. To the best of our knowledge, no similar case report has since been published in the literature. This case alerts the profession to the importance of drug–drug interaction and highlights the clinical features of digoxin toxicity.

scholarly journals Reports of Patients Consultation, Part 1 A Case Report of Digoxin Toxicity Presented with Visual Disturbance.

1998 ◽  
Vol 24 (6) ◽  
pp. 683-686
Author(s):  
MEGUMI MORII ◽  
KAZUYUKI UENO ◽  
MITSUTAKA TAKADA ◽  
SHIGEHO TAKARADA ◽  
SHIRO KAMAKURA ◽  
...  
Keyword(s):  
Case Report ◽  
Visual Disturbance ◽  
Digoxin Toxicity

scholarly journals Digoxin Toxicity presented with Right Bundle Branch Block: A Case report of Drug- Drug Interaction

2017 ◽  
Vol 5 (10) ◽  
pp. 921-924
Author(s):  
Dr. Shreya R Patel ◽  
◽  
Dr. Harsha D Makwana ◽  
Dr. Kamlesh P Patel ◽  
Dr. Supriya D Malhotra ◽  
...  
Keyword(s):  
Drug Interaction ◽  
Case Report ◽  
Right Bundle Branch Block ◽  
Digoxin Toxicity ◽  
Bundle Branch Block ◽  
Drug Drug Interaction

scholarly journals COVID-19 Pandemic Impact on Physicians’ Decision-making: Digoxin Toxicity in View of Combination of Hydroxychloroquine and Azithromycin: A Case Report

2020 ◽  
Vol 8 (T1) ◽  
pp. 150-153
Author(s):  
Mohammed Hamzah Mezaal ◽  
Hasan Ali Farhan ◽  
Zainab Atiyah Dakhil
Keyword(s):  
Decision Making ◽  
Case Report ◽  
Health Care Providers ◽  
Digoxin Toxicity ◽  
Care Providers ◽  
Global Pandemic ◽  
History Of ◽  
Multiple Levels ◽  
Evidence Based Therapy ◽  
Baseline Therapy

BACKGROUND: Since the WHO declaration of COVID-19 being a global pandemic, the population in general and health-care providers, in particular, became under extraordinary pressure that remarkably impacts their decisions at multiple levels as all of us should make decisions quickly while being uncertain in many times. CASE REPORT: We are reporting a 64-year-old lady with a medical history of atrial fibrillation and mitral regurgitation that treated with digoxin and warfarin therapy, she was suspected to be a COVID-19 case and prescribed empirical hydroxychloroquine and azithromycin combination without proper adjustment of her baseline therapy, accordingly she developed adverse effect of this combination in the form of digoxin toxicity and long QT, this case highlights how this unprecedented pandemic affects the decision-making of physicians. CONCLUSION: We should be critical and vigilant in making a decision of prescription or marketing non-evidence-based therapy, and when we are obligated for this decision, we should take all precautions to minimize the adverse effects of these drugs.

scholarly journals Severe suicidal digoxin toxicity managed with resin hemoperfusion: A case report

2012 ◽  
Vol 16 (4) ◽  
pp. 231-233 ◽  
Author(s):  
Manish Gupta ◽  
Omender Singh ◽  
Sanjay Saxena ◽  
Alka Bhasin ◽  
Archana Chaturvedi
Keyword(s):  
Case Report ◽  
Digoxin Toxicity

scholarly journals Xanthopsia Due to Digoxin Toxicity as a Cause of Traffic Accidents: A Case Report

2020 ◽  
Vol 21 ◽  
Author(s):  
Yusuke Haruna ◽  
Tatsuya Kawasaki ◽  
Yoko Kikkawa ◽  
Rentaro Mizuno ◽  
Satoaki Matoba
Keyword(s):  
Case Report ◽  
Traffic Accidents ◽  
Digoxin Toxicity

scholarly journals A CASE REPORT ON DIGOXIN INTOXICATION IN A CLINICAL PHARMACIST’S PERSPECTIVE

2018 ◽  
Vol 11 ◽  
Author(s):  
Saranya Punniyakotti ◽  
Benazeer Begum N
Keyword(s):  
Renal Function ◽  
Case Report ◽  
Drug Therapy ◽  
Drug Interactions ◽  
Therapeutic Range ◽  
Cardiac Failure ◽  
Digoxin Toxicity ◽  
Narrow Therapeutic Range ◽  
Digoxin Intoxication ◽  
Drug Therapy Problems

 Context: Digoxin is a commonly used inotropic drug that has a narrow therapeutic range and is monitored poorly for its plasma concentration. It is commonly used in the management of cardiovascular disorders for its inotropic effects. Increased risk of chronic digoxin toxicity among the patients receiving digoxin pharmacotherapy is related to its narrow therapeutic range. Apart from its inotropic properties, it can also produce chronotropic and dromotropic effect. Its serum levels vary due to changes in body weight, age, renal function, hepatic impairment, and concomitant drug administrations. Patients receiving digoxin should be monitored periodically for potential drug interactions, adverse effects, toxicity, and other drug-related problems. Symptoms of digoxin-induced cardiotoxicity are difficult to be identified and may become fatal too. Therapeutic drug monitoring will play a significant role in reducing such drug therapy problems and will ensure safety and efficacy of the given drug. Case Report: We report a case of chronic digoxin toxicity in a 22-year-old male with congestive cardiac failure - Class IV and atrial fibrillation with ventricular bigeminy. Results: Patient’s renal parameters were elevated and among electrolytes, sodium level was decreased and potassium level was increased. A reduction in the volume of the distribution of digoxin, due to impairment of renal function or congestive cardiac failure, might be one of the reasons for digoxin toxicity. Drug therapy problems (DTPs) such as untreated indication, inappropriate drug therapy, potential major drug-drug interactions, and drugs prescribed when contraindicated were observed. Conclusion: Monitoring digoxin drug therapy can bring down the risk of digoxin intoxication.

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