Treatment of vitamin D deficiency/insufficiency with ergocalciferol is associated with reduced vascular access dysfunction in chronic hemodialysis patients

2015 ◽  
Vol 19 (4) ◽  
pp. 499-508 ◽  
Author(s):  
Gaurav Agarwal ◽  
Karina Vasquez ◽  
Neena Penagaluru ◽  
Jonathan Gelfond ◽  
Wajeh Y. Qunibi
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Vascular Access ◽  
Hemodialysis Patients ◽  
Chronic Hemodialysis

Superficialization of Basilic Vein: Last Chance for a Native Arteriovenous Fistula in Hemodialysis Patients

2003 ◽  
Vol 4 (1) ◽  
pp. 21-24 ◽  
Author(s):  
M. Onaran ◽  
D. Erer ◽  
I. Şen ◽  
E.E. Elnur ◽  
E. Iriz ◽  
...  
Keyword(s):  
Arteriovenous Fistula ◽  
Vascular Access ◽  
Brachial Artery ◽  
Subcutaneous Tissue ◽  
Vascular Grafts ◽  
Hemodialysis Patients ◽  
Chronic Hemodialysis ◽  
Basilic Vein ◽  
Number Of Patients

Background Although the best type of vascular access for chronic hemodialysis patients is a native arteriovenous fistula, in an increasing number of patients all the superficial veins have been used and only the placement of vascular grafts or permanent catheters is left. Superficialization of the basilic vein is a possible alternative. Materials and Methods In 49 chronic hemodialysis patients who had no possibilities to have a native arteriovenous fistula created, we performed a basilic vein- brachial artery fistula in the arm. During the same operation the basilic vein was then superficialized for easier access for hemodialysis. Results Mean follow-up was 22.36±15.56 months. Forty-eight patients are still undergoing hemodialysis with their superficialized basilic vein native A-V fistula without any complications. Only one fistula was thrombosed just after the procedure because of poor vessel quality. Conclusion For hemodialysis patients who have no suitable superficial veins at the wrist or elbow, performing a basilic vein - brachial artery fistula and superficializing the vein to the subcutaneous tissue is an acceptable choice before deciding to use more complicated procedures like vascular grafts.

MO715PROFILE OF INFECTIVE ENDOCARDITIS IN HEMODIALYSIS PATIENTS

2021 ◽  
Vol 36 (Supplement_1) ◽  
Author(s):  
Samarra Badrouchi ◽  
Hajji Mariem ◽  
Samia Barbouch ◽  
Fethi Ben Hmida ◽  
Harzallah Amel ◽  
...  
Keyword(s):  
Infective Endocarditis ◽  
Vascular Access ◽  
Rare Complication ◽  
Hemodialysis Patients ◽  
Infectious Complications ◽  
Chronic Hemodialysis ◽  
Therapeutic Modalities ◽  
Duke Criteria ◽  
Profile Characteristics ◽  
Subclavian Catheter

Abstract Background and Aims Infectious complications are the second leading cause of death in hemodialysis patients. This population is particularly exposed to bacteremia, on the one hand, because of the vascular access necessary for hemodialysis, which is a gateway to the various micro-organisms, and on the other hand, factors of susceptibility to infections. Infective endocarditis (IE) is the cardiac endothelium infection associated with bacteremia. It is a rare complication but its mortality remains high especially in patients on chronic hemodialysis. The aim of this study was to determine the microbiological profile, clinical and-biological profile, characteristics in the ultrasound, therapeutic modalities, and prognosis of IE in hemodialysis. Method This is a retrospective descriptive study of including chronic hemodialysis patients, admitted in the Nephrology and Internal Medicine Department A of the Charles Nicolle Hospital in Tunis for an IE during the period from 1973 to 2018. We used the modified Duke criteria to confirm the diagnosis of IE. Results Nineteen patients were included, including 12 men and 7 women (gender ratio=1.7). The average age was 49.1 years [29-66 years]. Seven of them (37%) were known to have a valvular disease, two of them had a double mitro-aortic valve replacement. Six of them (32%) were diabetic and two patients (11%) were on immunosuppressive therapy. The vascular access initially used for HD were arteriovenous fistula in 9 cases (47%), internal jugular catheter in 3 cases (16%), subclavian catheter in 1 case (5%), Canaud catheter in 3 cases (16%), and 2 patients were dialyzed by femoral catheter (11%). Clinically, all patients had an altered general condition, fever was present in 14 cases (74%) and a heart murmur in 10 cases (53%). Blood cultures were positive in 14 cases (74%). The isolated germs were Staphylococcus Aureus in 8 cases, Staphylococcus epidermidis in 4 cases, Pseudomonas aerogenosa in 3 cases, Enterobacterium in 1 case, enterococcus faecalis in 1 case, and Klebsielle oxytoca in one patient. On cardiac ultrasound, mitral valve damage was found in 10 patients, aortic sigmoid in 4 patients and tricuspid valve in 3 patients. The treatment included appropriate antibiotic therapy in all cases and a valvuloplasty was indicated in 7 patients. Nine patients (47%) died during their hospitalization. Conclusion Hemodialysis patients are particularly exposed to IE. The most appropriate preventive method is the strict observance of asepsis when handling the vascular access first and the rapid eradication of all infectious outbreaks.

scholarly journals SP592INFLUENCE OF CYTOKINE GENE POLYMORPHISM ON VASCULAR ACCESS THROMBOSIS IN CHRONIC HEMODIALYSIS PATIENTS

2015 ◽  
Vol 30 (suppl_3) ◽  
pp. iii574-iii574
Author(s):  
Aleksandar Jankovic ◽  
Marko Barovic ◽  
Jelena Tosic-Dragovic ◽  
Petar Djuric ◽  
Ana Bulatovic ◽  
...  
Keyword(s):  
Gene Polymorphism ◽  
Vascular Access ◽  
Hemodialysis Patients ◽  
Chronic Hemodialysis ◽  
Cytokine Gene ◽  
Cytokine Gene Polymorphism

scholarly journals Assessment of Relationship Between Serum Vitamin D Levels and Metabolic Syndrome Components in Hemodialysis Patients

2021 ◽  
Vol 28 (1) ◽  
pp. E202113
Author(s):  
Sevil Karahan Yılmaz ◽  
Cuma Mertoğlu ◽  
Aylin Ayaz
Keyword(s):  
Metabolic Syndrome ◽  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Serum Vitamin ◽  
Vitamin D Insufficiency ◽  
Hemodialysis Patients ◽  
Hydroxyvitamin D ◽  
Serum Vitamin D ◽  
Vitamin D Levels ◽  
25 Oh Vitamin D

Aim: This study is aimed to evaluate the relationship between serum vitamin D levels and metabolic syndrome in hemodialysis patients. Materials and Methods: This study was conducted with participation of 80 patients undergoing hemodialysis for more than 6 months three times a week, aged > 18 years. Their height, dry weight, waist circumference were measured. Biochemical parameters such as serum 25-hydroxyvitamin D, lipid profile, and fasting blood glucose were analyzed. Metabolic syndrome was defined using the National Cholesterol Education Program Adult Treatment Panel III criteria. Severe vitamin D deficiency, 25 (OH) vitamin D < 5 ng/ml; mild vitamin D deficiency, 25 (OH) vitamin D 5-15 ng/ml; vitamin D insufficiency, 25 (OH) vitamin D 16-30 ng/ml, and vitamin D sufficiency, 25 (OH) vitamin D > 30 ng/ml were categorized. Statistical analysis of the data was performed with the use of SPSS version 21.0. Results: 48.4% of hemodialysis patients were identified to have metabolic syndrome. According to the serum levels of vitamin D; 35.0% of patients had severe vitamin D deficiency, 37.4% of patients had mild vitamin D deficiency, 18.8% of patients had vitamin D insufficiency and 8.8% of patients had vitamin D sufficiency (> 30 ng/ml). Vitamin D insufficiency was significantly associated with metabolic syndrome and central obesity. Conclusions: Deficiency/insufficiency is observed in serum 25-hydroxyvitamin D levels in hemodialysis patients. Vitamin D insufficiency is associated with metabolic syndrome.

scholarly journals Influence of secondary hyperparathyroidism in management anemia in patients on regular hemodialysis

2020 ◽  
Vol 77 (5) ◽  
pp. 508-515
Author(s):  
Nedim Hamzagic ◽  
Marija Andjelkovic ◽  
Marijana Stanojevic-Pirkovic ◽  
Petar Canovic ◽  
Vesna Ignjatovic ◽  
...  
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Iron Status ◽  
Hemodialysis Patients ◽  
Dialysis Adequacy ◽  
Hydroxyvitamin D ◽  
Reactive Protein ◽  
Severe Vitamin ◽  
Kolmogorov Smirnov ◽  
Regular Hemodialysis

Background/Aim. Anemia is a common complication in hemodialysis patients. Treatment of anemia is affected by iron deficiency, insufficient dose of erythropoietin, microinflammation, vitamin D deficiency, increased intact parathyroid hormone concentration and inadequate hemodialysis. The aim of the study was to determine the prevalence of vitamin D deficiency and its impact on hemoglobin con-centration, iron status, microinflammation, malnutrition, dialysis adequacy and erythropoietin dose in patients on regular hemodialysis. Methods. The study involved 120 patients divided into three groups: severely deficient of vitamin D: 25- hydroxyvitamin D[25(OH)D] < 10 ng/mL; deficient ? 25(OH)D within range of 10?20 ng/mL, and insufficient ? 25(OH)D > 20 ng/mL. For statistical analysis Kolmogorov- Smirnov test, the single-factor parametric analysis of variance ? ANOVA and Kruskal-Wallis test were used. Results. The prevalence of vitamin D deficiency in patients on regular hemodialysis was 75.83%, while the prevalence of severe vitamin D deficiency was 24.7%. Patients with severe vitamin D deficiency had lower blood concentration of hemoglobin, hematocrit, serum concentration of total proteins and albumin, and dialysis indices were also lower compared to the other two groups of patients. The level of C-reactive protein was significantly higher in the group of patients with severe vitamin D deficiency than in the two rest groups. Conclusion. Hemodialysis patients with severe vitamin D deficiency have lower hemoglobin, lower dialysis adequacy, significant microinflammation, malnutrition, bone metabolism disorders and need higher dose of erythropoietin than patients whose vitamin D was higher than 10 ng/mL. Vitamin D is important risk factor for development of anemia in hemodialysis patients and important factor that can affect treatment of anemia in these patients.

scholarly journals STATUS OF VITAMIN D IN CHRONIC HEMODIALYSIS PATIENTS

2020 ◽  
Vol 8 (3) ◽  
pp. 958-962
Author(s):  
Jamai I ◽  
◽  
El. Boukhrissi F. ◽  
Mahmoud M ◽  
◽  
...  
Keyword(s):  
Vitamin D ◽  
Hemodialysis Patients ◽  
Chronic Hemodialysis

scholarly journals Effect of vitamin D on sleep quality in hemodialysis patients

2020 ◽  
Vol 10 (4) ◽  
pp. e32-e32
Author(s):  
Narges Sadat Zahed ◽  
Maryam Namakchian ◽  
Zahra Davoudi ◽  
Adineh Taherkhani
Keyword(s):  
Vitamin D ◽  
Sleep Quality ◽  
Vitamin D Deficiency ◽  
Controlled Trial ◽  
Life Quality ◽  
Hemodialysis Patients ◽  
25 Hydroxy Vitamin D ◽  
The Mean ◽  
The Impact

Introduction: Quality of sleep is among the factors that affect the improvement of life quality. The previous studies showed that 50%-80% of hemodialysis patients experience sleeping disturbances. Additionally, dialysis patients commonly experience vitamin D deficiency. Objectives: We aimed to determine the impact of vitamin D deficiency therapy on sleep quality of hemodialysis patients. Patients and Methods: Thirty hemodialysis patients with 25-hydroxy vitamin D deficiency and Pittsburgh Sleep Quality Index (PSQI) ≥5 were enrolled in this clinical trial. Patients were treated with 50000-unit vitamin D per week for 12 weeks. After treatment, the PSQI score was recalculated for each patient. Results: Nineteen out of 30 patients (63.3%) were men and 11(36.7%) were women, with a mean age of 56.7 ± 14.3 years. The mean of vitamin D level was 18.61 ± 6.32 ng/mL before treatment and 41.14 ± 9.62 ng/mL after the treatment. The mean of PSQI score at the start of study was 9.97 and after treatment with vitamin D3, it was 9.47 (P > 0.05). Conclusion: Treatment of vitamin D deficiency did not have any effect on the sleep quality according to the PSQI score in hemodialysis patients. Trial registration: This randomized controlled trial was registered in the Iranian Registry of Clinical Trials (identifier: IRCT20200223046593N1; https://en.irct.ir/trial/46126, ethical code; IR.SBMU.RETECH.REC.1397.1277).

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