scholarly journals Predictive factors of immune tolerance treatment response in severe haemophilia A patients with inhibitors: A real‐world report from a single centre, mixed retrospective‐prospective long‐term study

Haemophilia ◽  
2019 ◽  
Vol 25 (2) ◽  
Author(s):  
Saturnino Haya ◽  
Carlos Solano ◽  
Ana Rosa Cid ◽  
Bienvenida Argilés ◽  
David Hervás ◽  
...  
Author(s):  
Ulf Kulau ◽  
Stephan Rottmann ◽  
Sebastian Schildt ◽  
Johannes van Balen ◽  
Lars Wolf

2013 ◽  
Vol 1 (1) ◽  
pp. 5-7
Author(s):  
Bert Leenders

Abstract Haemophilia A is an X-linked congenital bleeding disorder resulting from a deficiency of factor VIII (FVIII). Therapy to prevent or treat bleeding is by replacement of the missing FVIII. However, as a consequence of treatment, patients with HA may develop inhibitory IgG antibodies to FVIII, termed “inhibitors”. When this occurs, treatment becomes more complex and costly and morbidity increases. Inhibitor formation, occurring in up to 36% of patients with severe HA, is currently one of the most significant complications affecting patients with HA [1,2]. In these two case studies, the management of bleeds in patients with inhibitors, and the long-term inhibitor eradication will be discussed.


2014 ◽  
Vol 89 (11) ◽  
pp. 1047-1050 ◽  
Author(s):  
Francesca Palandri ◽  
Nicola Polverelli ◽  
Lucia Catani ◽  
Daria Sollazzo ◽  
Marco Romano ◽  
...  

Haemophilia ◽  
2018 ◽  
Vol 24 (3) ◽  
pp. 436-444 ◽  
Author(s):  
K. Vepsäläinen ◽  
P. Riikonen ◽  
R. Lassila ◽  
M. Arola ◽  
P. Huttunen ◽  
...  

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