Somatosensory profile of patients with haemophilia

Haemophilia ◽  
2017 ◽  
Vol 24 (1) ◽  
pp. 97-103 ◽  
Author(s):  
S. Krüger ◽  
M. K. Boettger ◽  
T. Hilberg
Keyword(s):  
Somatosensory Profile

scholarly journals Inherited erythromelalgia due to mutations inSCN9A:natural history, clinical phenotype and somatosensory profile

Brain ◽  
2016 ◽  
Vol 139 (4) ◽  
pp. 1052-1065 ◽  
Author(s):  
Aoibhinn McDonnell ◽  
Betsy Schulman ◽  
Zahid Ali ◽  
Sulayman D. Dib-Hajj ◽  
Fiona Brock ◽  
...  
Keyword(s):  
Clinical Phenotype ◽  
Somatosensory Profile

Somatosensory Profile Changes Evoked by Topical Application of Capsaicin to the Tongue in Healthy Individuals

2017 ◽  
Vol 31 (2) ◽  
pp. 139-146 ◽  
Author(s):  
Mika Honda ◽  
Lene Baad-Hansen ◽  
Takashi Iida ◽  
Osamu Komiyama ◽  
Misao Kawara ◽  
...  
Keyword(s):  
Topical Application ◽  
Healthy Individuals ◽  
Profile Changes ◽  
Somatosensory Profile

Effects of Experimental Pain and Lidocaine on Mechanical Somatosensory Profile and Face Perception

2017 ◽  
Vol 31 (2) ◽  
pp. 115-123 ◽  
Author(s):  
Yuri Costa ◽  
Eduardo Castrillon ◽  
Leonardo Bonjardim ◽  
Paulo Rodrigues Conti ◽  
Lene Baad-Hansen ◽  
...  
Keyword(s):  
Face Perception ◽  
Experimental Pain ◽  
Somatosensory Profile

scholarly journals Quantitative sensory phenotyping in chronic neuropathic pain patients treated with unilateral L4-dorsal root ganglion stimulation

2020 ◽  
Vol 18 (1) ◽  
Author(s):  
Thomas Kinfe ◽  
Nico von Willebrand ◽  
Andreas Stadlbauer ◽  
Michael Buchfelder ◽  
Thomas L. Yearwood ◽  
...  
Keyword(s):  
Dorsal Root Ganglion ◽  
Effect Size ◽  
Dorsal Root ◽  
Pain Syndrome ◽  
Sensory Profile ◽  
Reduction Of Pain ◽  
Somatosensory Profile ◽  
The One ◽  
The Impact ◽  
Pain Patients

Abstract Background In a previous study, we reported that selective dorsal root ganglion stimulation (DRGSTIM) at DRG level L4 promoted a favorable outcome for complex regional pain syndrome (CRPS) patients along with DRGSTIM-related changes of inflammatory biomarkers in blood and saliva. The impact on somatosensation is largely unknown. Herein, we assessed the quantitative sensory profile to quantify L4-DRGSTIM effects in CRPS patients. Methods Twelve refractory CRPS patients (4 female; 8 male; mean age 69 ± 9 years) received standardized quantitative sensory testing (QST) protocol at baseline and after 3 months of unilateral L4-DRGSTIM assessing nociceptive and non-nociceptive thermal and mechanical sensitivity of the knee affected by CRPS and the contralateral non-painful knee area. Results At baseline, CRPS subjects showed significantly increased thresholds for warmth, tactile and vibration detection (WDT, MDT and VDT) and exaggerated pain summation (WUR). After 3 months of unilateral L4-DRGSTIM all pain parameters exhibited trends towards normalization of sensitivity accumulating to a significant overall normalization for pain sensitivity (effect size: 0.91, p < 0.01), while with the one exception of WDT all non-nociceptive QST parameters remained unchanged. Overall change of non-nociceptive detection was negligible (effect size: 0.25, p > 0.40). Notably, reduction of pain summation (WUR) correlated significantly with pain reduction after 3 months of L4-DRGSTIM. Conclusions Selective L4-DRGSTIM lowered ongoing pain in CRPS patients and evoked significant normalization in the pain domain of the somatosensory profile. Thermoreception and mechanoreception remained unchanged. However, larger randomized, sham-controlled trials are highly warranted to shed more light on effects and mechanisms of dorsal root ganglion stimulation on quantitative sensory characteristics. The study protocol was registered at the 15.11.2016 on German Register for Clinical Trials (DRKS ID 00011267). https://www.drks.de/drks_web/navigate.do?navigationId=trial.HTML&TRIAL_ID=DRKS00011267

Topical High-Concentration (40%) Menthol—Somatosensory Profile of a Human Surrogate Pain Model

2011 ◽  
Vol 12 (7) ◽  
pp. 764-773 ◽  
Author(s):  
Andreas Binder ◽  
Maike Stengel ◽  
Oliver Klebe ◽  
Gunnar Wasner ◽  
Ralf Baron
Keyword(s):  
High Concentration ◽  
Pain Model ◽  
Somatosensory Profile

Somatosensory profile of a patient with mixed connective tissue disease and Sjögren syndrome

2020 ◽  
Vol 151 (2) ◽  
pp. 145-151
Author(s):  
Kana Ozasa ◽  
Chisa Nishihara ◽  
Kosuke Watanabe ◽  
Andrew Young ◽  
Junad Khan ◽  
...  
Keyword(s):  
Connective Tissue ◽  
Connective Tissue Disease ◽  
Mixed Connective Tissue Disease ◽  
Sjögren Syndrome ◽  
Sjogren Syndrome ◽  
Somatosensory Profile
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