scholarly journals Haemophilia and low bone mass. Ok, but what about fracture risk?

Haemophilia ◽  
2016 ◽  
Vol 22 (1) ◽  
pp. 11-14 ◽  
Author(s):  
P. Anagnostis ◽  
S. N. Karras ◽  
S. Vakalopoulou ◽  
E. Terpos
Keyword(s):  
Bone Mass ◽  
Fracture Risk ◽  
Low Bone Mass

Low Bone Mass and Severity of Cholestasis Affect Fracture Risk in Patients With Primary Biliary Cirrhosis

2010 ◽  
Vol 138 (7) ◽  
pp. 2348-2356 ◽  
Author(s):  
Núria Guañabens ◽  
Dacia Cerdá ◽  
Ana Monegal ◽  
Francesca Pons ◽  
Llorenç Caballería ◽  
...  
Keyword(s):  
Primary Biliary Cirrhosis ◽  
Bone Mass ◽  
Fracture Risk ◽  
Biliary Cirrhosis ◽  
Low Bone Mass

scholarly journals Characterization of Bone Metabolism in Hungarian Psoriatic Arthritis Patients: A Case–Control Study.

2020 ◽  
Author(s):  
Zsofia Petho ◽  
Edit Kalina ◽  
Zoltan Pap ◽  
Katalin Hodosi ◽  
Rebeka Falcsik ◽  
...  
Keyword(s):  
Psoriatic Arthritis ◽  
Bone Mass ◽  
Fracture Risk ◽  
Disease Activity ◽  
Bone Metabolism ◽  
Osteoporotic Fracture ◽  
Independent Predictor ◽  
Low Bone Mass ◽  
Major Osteoporotic Fracture ◽  
Volumetric Bmd

Abstract Background: Skeletal manifestations are predominant in psoriatic arthritis (PsA). The aim of this cross-sectional, case-controlled study is the complex assessment of areal and volumetric bone mineral density (BMD), fracture risk, vitamin D status and bone turnover markers, and its association with disease-related variables.Methods: Lumbar spine (L1-L4) and femur neck (FN) areal, and distal radius (DR) volumetric BMD, 10-year probability of major and hip osteoporotic fracture as assessed by the fracture risk assessment (FRAX) tool, markers of bone metabolism and disease activity were assessed.Results: Upon comparison of the disease and age- and sex-matched control groups, there was a statistically significant difference in FN areal (0.955±0.145 g/cm2 vs. 1.034±0.148 g/cm2; p=0.001) and DR total volumetric (285.7±61.8 mg/cm3 vs. 369.6±23.6 mg/cm3; p<0.001) BMD, 10 year probability for major osteoporotic (5.0% (0.7%-32%) vs. 3.5% (0%-17.5%); p=0.003) and hip (1.1% (0%-16%) vs. 0.5% (0%-6.1%); p=0.002) fracture and 25-hydroxyvitamin D status (53 (10-120) nmol/L vs. 67 (10-137; p<0.001) nmol/L). As compared to areal assessment, volumetric BMD measurements identified a significantly higher number of patients with low bone mass (T-Score £ -1.00) (34% vs. 88%, p<0.001). Upon multiple linear regression analysis, disease activity score, as determined by DAS28 assessment, was an independent predictor of 10-year probability for major osteoporotic fracture (B (95%CI) = 1.351 (0.379–2.323); p = 0.007).Conclusion: In the studied PsA cohort, disease activity was an independent predictor of 10-year probability for a major osteoporotic fracture, and complemented assessment of volumetric and areal BMD assured better efficacy at identifying those with low bone mass.

ESTIMATION OF LOW BONE MASS FOR THE ASSESSMENT OF OSTEOPOROSIS FRACTURE RISK IN INDIAN MEN AND WOMEN USING QUANTITATIVE ULTRASOUND AND DUAL ENERGY X-RAY ABSORPTIOMETRY

2004 ◽  
Vol 04 (01) ◽  
pp. 47-59 ◽  
Author(s):  
MALLIKARJUN S. HOLI ◽  
S. RADHAKRISHNAN
Keyword(s):  
Bone Mineral Density ◽  
Bone Mass ◽  
Fracture Risk ◽  
Quantitative Ultrasound ◽  
Dual Energy ◽  
Low Bone Mass ◽  
Mineral Density ◽  
Men And Women ◽  
X Ray ◽  
Indian Men

The objective of the present work is to estimate the prevalence of low bone mass in Indian men and women for the assessment of osteoporosis and fracture risk using quantitative ultrasound and dual energy X-ray absorptiometry (DEXA) and carryout a comparative evaluation for early prediction of osteoporosis. Data collected in this study is analyzed to assess the diagnostic performance of the ultrasound and how its performance compares to DEXA bone mineral density (BMD). Quantitative ultrasound assessment of osteoporosis is carried out by measuring broadband ultrasound attenuation (BUA) and speed of sound (SOS) through calcaneus bone to provide a clinical measure called the stiffness index (SI). The SI is a measure of bone density used to predict the risk of bone fracture due to osteoporosis. Bone mineral density (BMD) measurement is performed in lumbar region (L1–L4) of the spine in anterior-posterior direction using DEXA. In both studies the data is found to be significant in men and women subjects with p<0.0005 and percentage bone loss in men and women are significantly matching in both studies. Ultrasound performance correlates moderately well with DEXA (r=0.60 to 0.68) and provides comparable diagnostic sensitivity to spine BMD in predicting osteoporotic fractures.

Low Bone Mass and Postfall Fracture Risk Among Elderly Nursing Home Men

2004 ◽  
Vol 5 (6) ◽  
pp. 367-370 ◽  
Author(s):  
Nizaamuddeen Toofanny ◽  
Michael E. Maddens ◽  
John Voytas ◽  
Debra Kowalski
Keyword(s):  
Nursing Home ◽  
Bone Mass ◽  
Fracture Risk ◽  
Low Bone Mass
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