Chronic myelomonocytic leukaemia associated with acquired haemophilia A: case report and literature review

Haemophilia ◽  
2015 ◽  
Vol 21 (4) ◽  
pp. e341-e343 ◽  
Author(s):  
Y. Liang ◽  
R.-N. Lu ◽  
R. Wang ◽  
J.-F. Zhang ◽  
W. Su ◽  
...  
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Haemophilia A ◽  
Acquired Haemophilia ◽  
Chronic Myelomonocytic Leukaemia

scholarly journals Emicizumab in the Treatment of Acquired Haemophilia: A Case Report

2019 ◽  
Vol 46 (2) ◽  
pp. 121-123 ◽  
Author(s):  
Patrick Möhnle ◽  
Isabell Pekrul ◽  
Michael Spannagl ◽  
Andreas Sturm ◽  
Delila Singh ◽  
...  
Keyword(s):  
Case Report ◽  
Haemophilia A ◽  
Acquired Haemophilia

scholarly journals Acquired haemophilia A: a case report

2017 ◽  
Vol 3 ◽  
pp. 227-231
Author(s):  
Adam Stemplewski ◽  
Paulina Stemplewska ◽  
Paulina Gorzelak-Pabiś ◽  
Marlena Broncel
Keyword(s):  
Case Report ◽  
Haemophilia A ◽  
Acquired Haemophilia

scholarly journals Emicizumab in acquired haemophilia A: about two clinical cases and literature review

2021 ◽  
Vol 12 ◽  
pp. 204062072110381
Author(s):  
Amandine Hansenne ◽  
Cedric Hermans
Keyword(s):  
Autoimmune Disease ◽  
Literature Review ◽  
Factor Viii ◽  
Immunosuppressive Therapy ◽  
Current Literature ◽  
Mode Of Action ◽  
Bispecific Antibody ◽  
Haemophilia A ◽  
Acquired Haemophilia ◽  
Excess Morbidity

Acquired haemophilia A (AHA) is a rare and severe haemorrhagic autoimmune disease caused by autoantibodies directed against factor VIII (FVIII). Treatment is based on two principles, including haemostatic control to compensate FVIII inhibition and eradication of inhibiting antibodies using immunosuppressive therapy. Rapid recognition and proper management are essential to avoid excess morbidity and mortality. Effective and safe treatments can be challenging, given that AHA patients are often elderly, with multiple comorbidities. Emicizumab, a bispecific antibody that mimics the action of FVIII, has proven effective in managing patients with congenital haemophilia, with or without inhibitors. Likewise, its mode of action suggests theoretical efficacy in AHA patients. We herein describe two AHA cases with comorbidities that were treated effectively using emicizumab combined with immunosuppressive therapy. We have also reviewed the current literature regarding the promising use of emicizumab in this indication.

scholarly journals Mucormycosis presenting with dental pain and palatal ulcer in a patient with chronic myelomonocytic leukaemia: case report and literature review

2015 ◽  
Vol 2 (1) ◽  
Author(s):  
Ourania Nicolatou‐Galitis ◽  
Sotirios Sachanas ◽  
Maria Drogari‐Apiranthitou ◽  
Maria Moschogiannis ◽  
Dimitra Galiti ◽  
...  
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Dental Pain ◽  
Chronic Myelomonocytic Leukaemia

Acquired haemophilia A as a secondary autoimmune disease after alemtuzumab treatment in multiple sclerosis: A case report

2019 ◽  
Vol 27 ◽  
pp. 403-405 ◽  
Author(s):  
M. Pisa ◽  
P. Della Valle ◽  
A. Coluccia ◽  
V. Martinelli ◽  
G. Comi ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Case Report ◽  
Autoimmune Disease ◽  
Haemophilia A ◽  
Acquired Haemophilia

Acquired haemophilia B: a case report and literature review

2011 ◽  
Vol 69 (6) ◽  
pp. 685-688 ◽  
Author(s):  
Inès Jedidi ◽  
Sondes Hdiji ◽  
Naourez Ajmi ◽  
Faiza Makni ◽  
Sayda Masmoudi ◽  
...  
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Haemophilia B ◽  
Acquired Haemophilia

Two cases of acquired haemophilia A associated with chronic myelomonocytic leukaemia

2013 ◽  
Vol 24 (6) ◽  
pp. 655-657 ◽  
Author(s):  
Noppacharn Uaprasert ◽  
Supakanya Wongrakpanich ◽  
Ponlapat Rojnuckarin
Keyword(s):  
Haemophilia A ◽  
Acquired Haemophilia ◽  
Chronic Myelomonocytic Leukaemia

Efficacy of therapeutic plasma exchange in a patient with coagulation inhibitors (acquired haemophilia A) – A case report

2020 ◽  
Vol 59 (4) ◽  
pp. 102809
Author(s):  
Sangeeta Kumari ◽  
Parmatma Prasad Tripathi ◽  
Ratti Ram Sharma ◽  
Rekha Hans ◽  
Divjot Singh Lamba ◽  
...  
Keyword(s):  
Case Report ◽  
Plasma Exchange ◽  
Therapeutic Plasma Exchange ◽  
Haemophilia A ◽  
Acquired Haemophilia ◽  
Coagulation Inhibitors
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