scholarly journals Establishment and characterization of highly osteolytic luminal breast cancer cell lines by intracaudal arterial injection

2020 ◽  
Vol 25 (2) ◽  
pp. 111-123 ◽  
Author(s):  
Yuxuan Han ◽  
Jun Nakayama ◽  
Yusuke Hayashi ◽  
Seongmoon Jeong ◽  
Mitsuru Futakuchi ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cell Lines ◽  
Cancer Cell ◽  
Breast Cancer Cell ◽  
Cancer Cell Lines ◽  
Breast Cancer Cell Lines ◽  
Luminal Breast Cancer ◽  
Luminal Breast Cancer Cell

scholarly journals MiR-23a modulates X-linked inhibitor of apoptosis-mediated autophagy in human luminal breast cancer cell lines

Oncotarget ◽  
2017 ◽  
Vol 8 (46) ◽  
pp. 80709-80721 ◽  
Author(s):  
Ping Chen ◽  
Yin-Huan He ◽  
Xing Huang ◽  
Si-Qi Tao ◽  
Xiao-Nan Wang ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cell Lines ◽  
Cancer Cell ◽  
Breast Cancer Cell ◽  
Cancer Cell Lines ◽  
Breast Cancer Cell Lines ◽  
Inhibitor Of Apoptosis ◽  
Luminal Breast Cancer ◽  
Luminal Breast Cancer Cell

scholarly journals MicroRNA-Dependent Targeting of RSU1 and the IPP Adhesion Complex Regulates the PTEN/PI3K/AKT Signaling Pathway in Breast Cancer Cell Lines

2020 ◽  
Vol 21 (15) ◽  
pp. 5458
Author(s):  
Yong-Chul Kim ◽  
Mary L. Cutler
Keyword(s):  
Breast Cancer ◽  
Cell Lines ◽  
Cancer Cell ◽  
Breast Cancer Cell ◽  
Cancer Cell Lines ◽  
P38 Map Kinase ◽  
Breast Cancer Cell Lines ◽  
Luminal Breast Cancer ◽  
Control Of Gene Expression ◽  
Luminal Breast Cancer Cell

(1) Background: The microRNA (miR)-directed control of gene expression is correlated with numerous physiological processes as well as the pathological features of tumors. The focus of this study is on the role of miRs in the regulation of RSU1 and proteins in the IPP (integrin linked kinase, PINCH and parvin) complex. Because the IPP adaptor proteins link β integrins to actin cytoskeleton, and the RSU1 signaling protein connects the complex to the activation of cJun, ATF2 and the transcription of PTEN, their reduction by miRs has the potential to alter both adhesion and survival signaling. (2) Methods: Multiple database analyses were used to identify miRs that target RSU1 and PINCH1. miR transfection validated the effects of miRs on RSU1, PINCH1 and downstream targets in breast cancer cell lines. (3) Results: The miRs targeting RSU1 mRNA include miR-182-5p, -409-3p, -130a-3p, -221-3p, -744-5p and -106b-5p. Data show that miR-182-5p and -409-3p reduce RSU1, PINCH1 and inhibit the ATF2 activation of PTEN expression. miR-221-3p and miR-130a-3p target RSU1 and PINCH1 and, conversely, RSU1 depletion increases miR-221-3p and miR-130a-3p. (4) Conclusions: miRs targeting RSU1 and PINCH1 in mammary epithelial or luminal breast cancer cell lines reduced RSU1 signaling to p38 MAP kinase and ATF2, inhibiting the expression of PTEN. miR-221-3p, known to target PTEN and cell cycle regulators, also targets RSU1 and PINCH1 in luminal breast cancer cell lines.

scholarly journals Distinct characterization of two vinorelbine-resistant breast cancer cell lines developed by different strategies

2016 ◽  
Vol 35 (4) ◽  
pp. 2355-2363 ◽  
Author(s):  
MINGJIE XU ◽  
DONGHAI JIANG ◽  
JIAYING SHEN ◽  
HUILIN ZHENG ◽  
WEIMIN FAN
Keyword(s):  
Breast Cancer ◽  
Cell Lines ◽  
Cancer Cell ◽  
Breast Cancer Cell ◽  
Cancer Cell Lines ◽  
Breast Cancer Cell Lines ◽  
Resistant Breast Cancer Cell

Establishment and Characterization of New Murine Breast Cancer Cell Lines

2002 ◽  
Vol 335 (2-3) ◽  
pp. 55-68 ◽  
Author(s):  
Günther Bernhardt ◽  
Karin Beckenlehner ◽  
Thilo Spruß ◽  
Richard Schlemmer ◽  
Herta Reile ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cell Lines ◽  
Cancer Cell ◽  
Breast Cancer Cell ◽  
Cancer Cell Lines ◽  
Breast Cancer Cell Lines ◽  
Murine Breast Cancer Cell
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