Biliary pseudolithiasis in an older patient treated with lascufloxacin

2021 ◽  
Author(s):  
Takahiko Nagamine
Keyword(s):  
Older Patient ◽  
Biliary Pseudolithiasis

Audiologic Management of the Older Patient

ASHA Leader ◽  
2009 ◽  
Vol 14 (11) ◽  
pp. 14-17
Author(s):  
Harvey Abrams
Keyword(s):  
Older Patient

Assessment of the older patient with chronic kidney disease and polypharmacy − the perspective of the family doctor

Medic ro ◽  
2018 ◽  
Vol 5 (125) ◽  
pp. 33
Author(s):  
Liliana-Ana Tuţă ◽  
Laura Condur ◽  
Alina Mihaela Stăniguţ ◽  
Camelia Pană
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Family Doctor ◽  
Older Patient ◽  
The Family

The older patient presenting with itch and a recent medication change

2020 ◽  
Vol 49 (5) ◽  
pp. 277-279
Author(s):  
Lauren Maree Turner ◽  
Shelley Ji Eu Hwang ◽  
Genevieve Bennett ◽  
Andrew C Miller
Keyword(s):  
Older Patient ◽  
Medication Change

The Role of Radiation Therapy in the Older Patient

2021 ◽  
Vol 23 (1) ◽  
Author(s):  
Ammoren Dohm ◽  
Roberto Diaz ◽  
Ronica H. Nanda
Keyword(s):  
Radiation Therapy ◽  
Older Patient

ASPERGILLUS FLAVUSMENINGITIS AND PONTINE HEMORRHAGE IN AN OLDER PATIENT

1996 ◽  
Vol 44 (6) ◽  
pp. 739-740 ◽  
Author(s):  
A. Adunsky ◽  
E. Rubinstein ◽  
A. Goldsmith
Keyword(s):  
Older Patient ◽  
Pontine Hemorrhage

scholarly journals Single modality radical radiotherapy is an acceptable alternative for the older patient with squamous cell carcinoma of the oesophagus

2021 ◽  
Vol 8 (1) ◽  
pp. e000492
Author(s):  
Sarah Derby ◽  
Matthew Forshaw ◽  
Caroline Lowrie ◽  
Derek Grose ◽  
Husam Marashi ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Cox Regression ◽  
Multimodality Treatment ◽  
Radical Radiotherapy ◽  
Older Patient ◽  
Older Population ◽  
Cox Regression Analysis ◽  
Significant Difference

BackgroundOesophageal cancer remains a common cause of cancer mortality worldwide. Increasingly, oncology centres are treating an older population and comorbidities may preclude multimodality treatment with chemoradiotherapy (CRT). We review outcomes of radical radiotherapy (RT) in an older population treating squamous cell carcinoma (SCC) oesophagus.MethodsPatients over 65 years receiving RT for SCC oesophagus between 2013 and 2016 in the West of Scotland were identified. Kaplan-Meier and Cox-regression analysis were used to compare overall survival (OS) between patients treated with radical RT and radical CRT.ResultsThere were 83 patients over 65 years treated with either RT (n=21) or CRT (n=62). There was no significant difference in median OS between CRT versus RT (26.8 months vs 28.5 months, p=0.92). All patients receiving RT completed their treatment whereas 11% of CRT patients did not complete treatment.ConclusionSurvival in this non-trial older patient group managed with CRT is comparable to that reported in previous trials. RT shows better than expected outcomes which may reflect developments in RT technique. This review supports RT as an alternative in older patients, unfit for concurrent treatment.

scholarly journals Undifferentiated pleomorphic sarcoma in oropharyngeal mucosa of patients with multiple basal cell carcinomas

Rare Tumors ◽  
2021 ◽  
Vol 13 ◽  
pp. 203636132110264
Author(s):  
Andrea Dekanić ◽  
Marko Velepič ◽  
Margita Belušić Gobić ◽  
Ita Hadžisejdić ◽  
Nives Jonjić
Keyword(s):  
Differential Diagnosis ◽  
Basal Cell ◽  
Polypoid Lesion ◽  
Older Patient ◽  
Mesenchymal Tumors ◽  
Undifferentiated Pleomorphic Sarcoma ◽  
Pleomorphic Sarcoma ◽  
Basal Cell Carcinomas ◽  
History Of ◽  
Multiple Basal Cell Carcinomas

Malignant mesenchymal tumors of oropharyngeal mucosa are rare. Those with fibroblastic and histiocytic differentiation in the skin are called atypical fibroxanthoma (AFX) and in the soft tissue undifferentiated pleomorphic sarcoma (UPS). Here we present a case of an older patient with a history of multiple basal cell carcinomas and recently with a rapidly growing polypoid lesion in the mucosa of posterior oropharyngeal wall with AFX/UPS morphology. The differential diagnosis, histological pitfalls of this poorly characterized mesenchymal lesions, and the challenges associated with treatment are discussed.

scholarly journals Better Medicines for Older Patients: Considerations between Patient Characteristics and Solid Oral Dosage Form Designs to Improve Swallowing Experience

Pharmaceutics ◽  
2020 ◽  
Vol 13 (1) ◽  
pp. 32
Author(s):  
Nélio Drumond ◽  
Sven Stegemann
Keyword(s):  
Patient Population ◽  
Older Patients ◽  
Negative Impact ◽  
Water Soluble ◽  
Oral Dosage ◽  
Oral Drug ◽  
Older Patient ◽  
Coating Materials ◽  
Esophageal Transit ◽  
Patient Centric

Oral drug administration provided as solid oral dosage forms (SODF) remains the major route of drug therapy in primary and secondary care. There is clear evidence for a growing number of clinically relevant swallowing issues (e.g., dysphagia) in the older patient population, especially when considering the multimorbid, frail, and polymedicated patients. Swallowing impairments have a negative impact on SODF administration, which leads to poor adherence and inappropriate alterations (e.g., crushing, splitting). Different strategies have been proposed over the years in order to enhance the swallowing experience with SODF, by using conventional administration techniques or applying swallowing aids and devices. Nevertheless, new formulation designs must be considered by implementing a patient centric approach in order to efficiently improve SODF administration by older patient populations. Together with appropriate SODF size reductions, innovative film coating materials that can be applied to SODF and provide swallowing safety and efficacy with little effort being required by the patients are still needed. With that in mind, a literature review was conducted in order to identify the availability of patient centric coating materials claiming to shorten esophageal transit times and improve the overall SODF swallowing experience for older patients. The majority of coating technologies were identified in patent applications, and they mainly included well-known water soluble polymers that are commonly applied into pharmaceutical coatings. Nevertheless, scientific evidence demonstrating the benefits of given SODF coating materials in the concerned patient populations are still very limited. Consequently, the availability for safe, effective, and clinically proven solutions to address the increasing prevalence of swallowing issues in the older patient population is still limited.

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