scholarly journals Impact of long-hours family caregiving on non-fatal coronary heart disease risk in middle-aged people: Results from a longitudinal nationwide survey in Japan

2017 ◽  
Vol 17 (11) ◽  
pp. 2109-2115 ◽  
Author(s):  
Atsushi Miyawaki ◽  
Jun Tomio ◽  
Yasuki Kobayashi ◽  
Hideto Takahashi ◽  
Haruko Noguchi ◽  
...  
PLoS ONE ◽  
2015 ◽  
Vol 10 (9) ◽  
pp. e0139651 ◽  
Author(s):  
Katherine E. Beaney ◽  
Jackie A. Cooper ◽  
Saleem Ullah Shahid ◽  
Waqas Ahmed ◽  
Raheel Qamar ◽  
...  

Circulation ◽  
1998 ◽  
Vol 98 (5) ◽  
pp. 398-404 ◽  
Author(s):  
Marja Pyörälä ◽  
Heikki Miettinen ◽  
Markku Laakso ◽  
Kalevi Pyörälä

2016 ◽  
Vol 183 (8) ◽  
pp. 729-738 ◽  
Author(s):  
Chantal M. Koolhaas ◽  
Klodian Dhana ◽  
Rajna Golubic ◽  
Josje D. Schoufour ◽  
Albert Hofman ◽  
...  

2020 ◽  
Vol 11 (1) ◽  
Author(s):  
Soodabeh Milanlouei ◽  
Giulia Menichetti ◽  
Yanping Li ◽  
Joseph Loscalzo ◽  
Walter C. Willett ◽  
...  

AbstractEnvironmental factors, and in particular diet, are known to play a key role in the development of Coronary Heart Disease. Many of these factors were unveiled by detailed nutritional epidemiology studies, focusing on the role of a single nutrient or food at a time. Here, we apply an Environment-Wide Association Study approach to Nurses’ Health Study data to explore comprehensively and agnostically the association of 257 nutrients and 117 foods with coronary heart disease risk (acute myocardial infarction and fatal coronary heart disease). After accounting for multiple testing, we identify 16 food items and 37 nutrients that show statistically significant association – while adjusting for potential confounding and control variables such as physical activity, smoking, calorie intake, and medication use – among which 38 associations were validated in Nurses’ Health Study II. Our implementation of Environment-Wide Association Study successfully reproduces prior knowledge of diet-coronary heart disease associations in the epidemiological literature, and helps us detect new associations that were only marginally studied, opening potential avenues for further extensive experimental validation. We also show that Environment-Wide Association Study allows us to identify a bipartite food-nutrient network, highlighting which foods drive the associations of specific nutrients with coronary heart disease risk.


2016 ◽  
Vol 36 (9) ◽  
pp. 2011-2018 ◽  
Author(s):  
Jaike Praagman ◽  
Ester A.L. de Jonge ◽  
Jessica C. Kiefte-de Jong ◽  
Joline W.J. Beulens ◽  
Ivonne Sluijs ◽  
...  

2008 ◽  
Vol 197 (2) ◽  
pp. 556-563 ◽  
Author(s):  
J.A. Troughton ◽  
J.V. Woodside ◽  
J.W.G. Yarnell ◽  
D. Arveiler ◽  
P. Amouyel ◽  
...  

2006 ◽  
Vol 187 (1) ◽  
pp. 110-115 ◽  
Author(s):  
Marijke J.C.A. van Trijp ◽  
Willem J.W. Bos ◽  
Yvonne T. van der Schouw ◽  
Majon Muller ◽  
Diederick E. Grobbee ◽  
...  

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