Effect of elastic band-based high-speed power training on cognitive function, physical performance and muscle strength in older women with mild cognitive impairment

2016 ◽  
Vol 17 (5) ◽  
pp. 765-772 ◽  
Author(s):  
Dong Hyun Yoon ◽  
Dongheon Kang ◽  
Hee-jae Kim ◽  
Jin-Soo Kim ◽  
Han Sol Song ◽  
...  
2019 ◽  
Vol 48 (Supplement_4) ◽  
pp. iv18-iv27
Author(s):  
Yu Chi Heaw ◽  
Devinder Kaur Ajit Singh ◽  
Maw Pin Tan ◽  
Saravana Kumar

Abstract Introduction While mild cognitive impairment (MCI) is a risk factor for falls in older adults, the effects of MCI on physical performance associated with MCI have not been adequately characterised. The aim of the study was to profile physical performance patterns associated with MCI. Methodology 53 older fallers (31 females, 22 males) from the Falls Clinic at Universiti Malaya Medical Centre, aged 60 years and above (76.5±6.6) were screened and categorised into 2 groups – with MCI and non-MCI – using a Visual Cognitive Assessment Test (VCAT) cut-off score of ≥23. Participants’ sociodemographic data were recorded. Participants performed the Senior Fitness Test that consisted of a battery of physical performance tests. Results Older fallers with MCI (n=26) had significantly (p<0.05) poorer physical performance compared to the non-MCI (n=27) group in handgrip strength (16.7±4.8 vs 20.7±7.9 kg), Timed Up-and-Go (17.3±9.91 vs 9.54±2.10 s) and 2-minute walk (79.3±29.8 vs MCI 106.3±33.1 m) tests. There were no significant (p>0.05) differences for the 30-second chair stand, chair sit-and-reach and back scratch tests. Conclusion Older fallers with MCI had poorer upper body muscle strength, balance and aerobic endurance compared to those with normal cognition. However, flexibility and lower body muscle strength were similar in older fallers with and without MCI. Further studies to evaluate specifically tailored interventions according to the pattern of physical impairment reported with MCI are needed.


2021 ◽  
Vol 12 ◽  
Author(s):  
Jindong Chang ◽  
Wenbing Zhu ◽  
Jia Zhang ◽  
Liming Yong ◽  
Ming Yang ◽  
...  

The present study aimed to assess the effects of square dance exercise on the cognitive function and quality of life in older women with mild cognitive impairment and to investigate the mediating role of a depressed mood and reduced quality of life in the relationship between square dance exercise and cognition. The study design was a single-blind whole-group controlled trial. A total of 136 eligible participants were divided according to their nursing home into either an experimental or control group. The nursing home grouping was determined by the drawing of lots. The Montreal Cognitive Assessment (MoCA), Quality of Life (SF-12) and Geriatric Depression Scale (GDS-15) were used to assess participants at baseline, week 9, and week 18, respectively. Generalized estimating equations (GEE) were used to compare the results at baseline with mid-test and post-test changes in cognitive function and quality of life. Maximum likelihood estimation (ML) and robust standard errors were used to perform the mediation model. The study results indicated that the experimental group (compared to the control group) had a significant improvement in cognitive function, quality of life, and mood state at baseline in the mid-test and post-test results. The results of this 18-week experiment showed that the exercise–cognition relationship was significantly mediated by a reduction in depressive symptoms (indirect effect: β = −0.375; 95% CI = −0.864 to −0.069) and an improvement in quality of life (indirect effect: β = −0.678; 95% CI = −1.222 to −0.290). This study revealed the effects of moderate-intensity square dance exercise on cognitive function and quality of life in older Chinese women with mild cognitive impairment and explored the potential mediating mechanisms. These findings can be used to inform the development of public health policies to promote brain health in older adults with mild cognitive impairment.


2017 ◽  
Vol 30 (4) ◽  
pp. 753-759 ◽  
Author(s):  
Érica Carvalho Caldas ◽  
Lays Aragão Rezende ◽  
Karoline da Silva Oliveira ◽  
Hudson Azevedo Pinheiro ◽  
Gislane Ferreira de Melo ◽  
...  

Abstract Introduction: Mild cognitive impairment (MCI) is characterized by subjective memory complaints and is considered an intermediate stage between normal and pathological cognitive function. The decline in cognitive function may be associated with low functional performance and alterations in body composition in older adults. Objective: To assess muscle strength, lower extremity functional performance and body composition in elderly women with MCI. Methods: Forty-three elderly women (aged 60-80 years) participated in the study. Participants were divided into two groups: elderly women with MCI (n = 19) and elderly women without MCI (n = 24). To diagnose MCI, we used the instruments proposed by Petersen et al. According to it, the subjects had to have memory complaints that had no effects on basic or instrumental activities of daily living. Muscle strength was assessed via palmar grip strength (PGS) using a dynamometer (Jamar®) and knee extension strength (KES) was assessed using the one-repetition maximum test (1-RM). Lower extremity (LE) functional performance was assessed using the Short Physical Performance Battery (SPPB) and body composition was measured using biometrical impedance analysis (Biodynamics Model 310). Results: There was a significant difference in muscle strength between groups. The group with MCI had lower PGS (p = 0.002) and KES (p = 0.002), when compared to their counterparts. No significant difference between groups was found for the other variables, like SPPB and body composition. We found a positive, significant correlation between SPPB and KES (r = 0.55; p = 0.0001), SPPB and PGS (r = 0.37; p = 0.0155), KES and PGS (r = 0.59; p < 0.0001), and between lean mass and PGS (r = 0.36; p = 0.0184). Conclusion: Elderly women with MCI show reduced LE muscle strength and PGS, but no differences between groups were found for LE functional performance and body composition.


2020 ◽  
Vol 17 (6) ◽  
pp. 556-565
Author(s):  
Yujie Guo ◽  
Pengfei Li ◽  
Xiaojun Ma ◽  
Xiaochen Huang ◽  
Zhuoheng Liu ◽  
...  

Background: The present study was designed to examine the association of circulating cholesterol with cognitive function in non-demented community aging adults. Methods: This was a cross-sectional study including 1754 Chinese adults aged 55-80 years. The association between serum cholesterol levels and cognitive function was examined. Participants were categorized into four groups according to the quartile of circulating TC (total cholesterol), High Density Lipoprotein Cholesterol (HDL-c), Low Density Lipoprotein Cholesterol (LDL-c) levels and HDLc/ LDL-c ratio. The difference in cognitive performance among the groups was compared. Logistic regression model was used to determine the association of circulating cholesterol level with the risk of Mild Cognitive Impairment (MCI). Results: Mild increase of serum LDL-c level correlated with better visual and executive, language, memory and delayed recall abilities. Higher circulating TC and HDL-c levels were found to be associated with poorer cognitive function, especially in aging female subjects. Higher circulating TC, HDL-c and HDL/LDL ratio indicated an increased risk of MCI, especially in female subjects. Conclusion: Slight increase in circulating LDL-c level might benefit cognitive function in aging adults. However, higher circulating TC and HDL-c levels might indicate a decline of cognitive function, especially in aging female subjects.


2020 ◽  
Vol 16 (14) ◽  
pp. 1309-1315
Author(s):  
Peilin An ◽  
Xuan Zhou ◽  
Yue Du ◽  
Jiangang Zhao ◽  
Aili Song ◽  
...  

Background: Inflammation plays a significant role in the pathophysiology of cognitive impairment in previous studies. Neutrophil-lymphocyte ratio (NLR) is a reliable measure of systemic inflammation. Objective: The aim of this study was to investigate the association between NLR and mild cognitive impairment (MCI), and further to explore the diagnostic potential of the inflammatory markers NLR for the diagnosis of MCI in elderly Chinese individuals. Methods: 186 MCI subjects and 153 subjects with normal cognitive function were evaluated consecutively in this study. Neutrophil (NEUT) count and Lymphocyte (LYM) count were measured in fasting blood samples. The NLR was calculated by dividing the absolute NEUT count by the absolute LYM count. Multivariable logistic regression was used to evaluate the potential association between NLR and MCI. NLR for predicting MCI was analyzed using Receiver Operating Characteristic (ROC) curve analysis. Results: The NLR of MCI group was significantly higher than that of subjects with normal cognitive function (2.39 ± 0.55 vs. 1.94 ± 0.51, P < 0.001). Logistic regression analysis showed that higher NLR was an independent risk factor for MCI (OR: 4.549, 95% CI: 2.623-7.889, P < 0.001). ROC analysis suggested that the optimum NLR cut-off point for MCI was 2.07 with 73.66% sensitivity, 69.28% specificity, 74.48% Positive Predictive Values (PPV) and 68.36% negative predictive values (NPV). Subjects with NLR ≥ 2.07 showed higher risk relative to NLR < 2.07 (OR: 5.933, 95% CI: 3.467-10.155, P < 0.001). Conclusion: The elevated NLR is significantly associated with increased risk of MCI. In particular, NLR level higher than the threshold of 2.07 was significantly associated with the probability of MCI.


Author(s):  
Min-Ki Jeong ◽  
Kyung-Won Park ◽  
Je-Kwang Ryu ◽  
Gwon-Min Kim ◽  
Hyun-Hun Jung ◽  
...  

Age-related dementia refers to a state in which someone experiences multiple cognitive function impairment due to degenerative brain disease, and which causes difficulties in their daily life or social life. Dementia is the most common and serious obstacle in later life. Early intervention in the case of patients who are in the mild cognitive impairment (MCI) stage among the high-risk group can maintain and improve their cognitive function. The purpose of the current trial is aimed at investigating the association between a multi-component (exercise with cognitive) intervention program and habitual physical activity parameters on cognitive functions in MCI patients. Neuropsychological cognitive and depression assessments were performed by neuropsychologists according to normalized methods, including the Korean mini-mental State examination (K-MMSE) and modified Alzheimer’s disease assessment scale-cognitive subscale (ADAS-Cog) and cognitive assessment tool (attention, processing speed), and the Korean version of the geriatric depression scale (SGDS-K), both at baseline and at a 12 weeks follow-up. The 12-week multi-component intervention improved cognitive function and habitual physical activity parameters in patients with MCI relative to controls. A multi-component intervention program for patients with MCI is considered to be an effective method of dementia prevention by improving global (ADAS-Cog) and frontal (trail-making test, digit symbol substitution test) cognition and habitual physical activity parameters such as moderate to vigorous physical activity and step count. In addition, it is important to encourage habitual physical activities to ensure that exercise intervention strategies are carried out at the duration and intensity required for improving physical and cognitive wellbeing and obtaining health benefits.


2021 ◽  
pp. 1-9
Author(s):  
Anoop Sheshadri ◽  
Piyawan Kittiskulnam ◽  
Cynthia Delgado ◽  
Rebecca L. Sudore ◽  
Jennifer C. Lai ◽  
...  

<b><i>Introduction:</i></b> A randomized, controlled trial of a pedometer-based walking intervention with weekly activity goals led to increased walking among dialysis patients. We examined whether impairment per cognitive function screening is associated with adherence and performance in the intervention. <b><i>Methods:</i></b> Thirty dialysis patients were randomly assigned to a 3-month pedometer-based intervention with weekly goals. Participants were administered the Telephone Interview of Cognitive Status (TICS), a test of global mental status. We examined the association of levels of impairment on the TICS (≥33: unimpaired, 26–32: ambiguous impairment, 21–25: mild cognitive impairment [MCI]) with adherence, achieving weekly goals, and increasing steps, physical performance (Short Physical Performance Battery, SPPB), and self-reported physical function (PF) through multivariable linear mixed-model and logistic regression analyses adjusted for age, sex, BMI, dialysis modality, baseline steps, baseline SPPB, and stroke status. <b><i>Results:</i></b> One-third of participants were unimpaired, and 13% had MCI. Participants with worse results on cognitive function screening missed more calls and completed fewer weekly goals than participants with better results. During the intervention, a worse result on cognitive function screening was associated with smaller increases in steps compared to those without impairment: (ambiguous: −620 [95% CI −174, −1,415], MCI: −1,653 [95% CI −120, −3,187]); less improvement in SPPB (ambiguous: −0.22 points [95% CI −0.08, −0.44], MCI: −0.45 [95% CI −0.13, −0.77]); and less improvement in PF (ambiguous: −4.0 points [95% CI −12.2, 4.1], MCI: −14.0 [95% CI −24.9, −3.1]). During the postintervention period, a worse result on cognitive function screening was associated with smaller increases in SPPB (ambiguous: −0.54 [95% CI −1.27, 0.19], MCI: −0.97 [95% CI −0.37, −1.58]) and PF (ambiguous: −3.3 [95% CI −6.5, −0.04], MCI: −10.5 [95% CI −18.7, −2.3]). <b><i>Discussion/Conclusion:</i></b> Participants with worse results on cognitive function screening had worse adherence and derived less benefit from this pedometer-based intervention. Future exercise interventions should be developed incorporating methods to address cognitive impairment, for example, by including caregivers when planning such interventions.


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