scholarly journals Impact of night-time blood pressure on cerebral white matter hyperintensity in elderly hypertensive patients

2015 ◽  
Vol 15 ◽  
pp. 59-65 ◽  
Author(s):  
Manabu Kokubo ◽  
Atsuya Shimizu ◽  
Toko Mitsui ◽  
Motohiro Miyagi ◽  
Kenichiro Nomoto ◽  
...  
Keyword(s):  
Blood Pressure ◽  
White Matter ◽  
White Matter Hyperintensity ◽  
Cerebral White Matter ◽  
Night Time ◽  
Hypertensive Patients ◽  
Elderly Hypertensive ◽  
Elderly Hypertensive Patients

Abstract P190: Antihypertensive Treatment Improves Left Ventricular Geometry After 10 Years Even In Elderly Hypertensive Patients

Hypertension ◽  
2021 ◽  
Vol 78 (Suppl_1) ◽  
Author(s):  
Ayumi Toba ◽  
Joji Ishikawa ◽  
Kazumasa Harada
Keyword(s):  
Blood Pressure ◽  
Antihypertensive Treatment ◽  
Left Ventricular ◽  
Left Ventricular Geometry ◽  
Night Time ◽  
Hypertensive Patients ◽  
Ventricular Geometry ◽  
Elderly Hypertensive ◽  
Elderly Hypertensive Patients ◽  
The Impact

Introduction: Both ageing and high blood pressure (BP) is associated with a risk of left ventricular hypertrophy; therefore, it is unclear whether antihypertensive treatment for 10 years period reduce cardiac hypertrophy and concentricity beyond the impact of ageing. We assessed the hypothesis that even in elderly patients, BP reduction is effective for left ventricular remodeling. Methods: Among 558 hypertensive patients without concurrent heart disease referred to a cardiology clinic who underwent echocardiography and ambulatory blood pressure monitoring, 151 patients’ data of echocardiography was available after 10 years of follow up period. We evaluated the relation among BP at baseline, antihypertensive medications, and change in echocardiographic parameters of left ventricular geometry. Results: Mean age was 70.8±8.2 years at baseline. 24-hour BP was 127.4±16.4/71.4±9.6mmHg, awake BP was 129.9±17.1/72.4±10.2mmHg, and asleep BP was 122.5±16.9/67.1±9.1 mmHg. After 10 years (mean age 81.0±9.0 years), number of antihypertensive increased from 1.3±1.2 to 2.0±1.1. Left ventricular mass index (LVMI) insignificantly decreased from 115.7 to 98.7mg/m 2 (p=0.167)and relative wall thickness (RWT) significantly decreased from 0.51 to 0.47(p<0.001). There were 12% of patients with normal left ventricular geometry (N), 52% with concentric remodeling (CR), 9% with eccentric hypertrophy (EH), and 27% with concentric hypertrophy (CH) at baseline. Among patients with N or CR at baseline, those who developed to CH or EH had higher night time systolic BP (126.5±17.0 vs 118.9 ±15.4, p=0.037) than those who did not. Neither number nor type of antihypertensive was related to this geometry change. In logistic regression analysis, night time systolic BP was significantly related to the progression of hypertrophy adjusting for age, sex, BMI, LVMI, RWT, and clinic systolic BP at baseline (p=0.04). Conclusions: Even in elderly hypertensive patients, antihypertensive treatment for 10 years improved LV geometry in spite of ageing. Nighttime BP at baseline predicted worsening of LV geometry after 10 years beyond clinic BP.

The Effect of Prophylactic Ephedrine on Systemic Hypotension Caused by Induction of Anaesthesia with Propofol and Sufentanil in Elderly Hypertensive Patients: A Prospective Randomized, Double-blind Placebo-controlled Clinical Trial

2020 ◽  
Keyword(s):  
Blood Pressure ◽  
General Anesthesia ◽  
Normal Saline ◽  
Saline Group ◽  
Normal Saline Group ◽  
Hypertensive Patients ◽  
Group A ◽  
Elderly Hypertensive ◽  
Elderly Hypertensive Patients ◽  
Group B

Objective: To study the effectiveness of prophylactic ephedrine to prevent hypotension caused by induction of anesthesia with propofol and sufentanil in elderly hypertensive patients. Methodology: 70 elderly ASA grade II-III hypertensive patients undergoing elective general anesthesia were randomized into two groups to receive either intravenous ephedrine,100 ug/kg in 5ml normal saline (Group B), or an equal volume of normal saline (Group A) before induction. Systolic Blood Pressure (SBP), Diastolic Blood Pressure (DBP) and Heart Rate (HR) were recorded at T0 (after entry to the operating room), T1 (1 min after induction), T2 (2 min after induction), T3 ( 3 min after induction), T4 (4 min after induction), T5 (when intubated), T6 (2 min after intubation), and T7 (at the start of the procedure), as well as the incidence of hypotension and bradycardia. Results: SBP, DBP and HR were not significantly different at T0 and were significantly different at T1 to T7 after anesthesia induction. There were statistically significant effect on hypotension and bradycardia between the two groups and group B have a lower risk of hypotension and bradycardia relative to group A. SBP and DBP decreased significantly after induction in both groups. HR decreased significantly in group A while increased in group B. Conclusion: Ephedrine pretreatment can minimize hypotension and bradycardia caused by propofol and sufentanil during the induction of general anesthesia in elderly patients with hypertension.

Nocturnal Fall of Blood Pressure and Silent Cerebrovascular Damage in Elderly Hypertensive Patients

Hypertension ◽  
1996 ◽  
Vol 27 (1) ◽  
pp. 130-135 ◽  
Author(s):  
Kazuomi Kario ◽  
Takefumi Matsuo ◽  
Hiroko Kobayashi ◽  
Masahiro Imiya ◽  
Miyako Matsuo ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Hypertensive Patients ◽  
Elderly Hypertensive ◽  
Elderly Hypertensive Patients

scholarly journals Postexercise blood pressure reduction in elderly hypertensive patients

2002 ◽  
Vol 39 (4) ◽  
pp. 676-682 ◽  
Author(s):  
Maria Urbana P Brandão Rondon ◽  
Maria Janieire N.N Alves ◽  
Ana Maria F.W Braga ◽  
Odila Tomoko U.N Teixeira ◽  
Antonio Carlos P Barretto ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Blood Pressure Reduction ◽  
Pressure Reduction ◽  
Hypertensive Patients ◽  
Elderly Hypertensive ◽  
Elderly Hypertensive Patients

Ambulatory Blood Pressure Monitoring as a Means to Avoid Overtreatment of Elderly Hypertensive Patients

Gerontology ◽  
1992 ◽  
Vol 38 (1-2) ◽  
pp. 99-104 ◽  
Author(s):  
Olivier Raccaud ◽  
Bernard Waeber ◽  
Antonio Petrillo ◽  
Paul Wiesel ◽  
Jean-René Hofstetter ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Ambulatory Blood Pressure Monitoring ◽  
Ambulatory Blood Pressure ◽  
Blood Pressure Monitoring ◽  
Pressure Monitoring ◽  
Hypertensive Patients ◽  
Elderly Hypertensive ◽  
Elderly Hypertensive Patients
Sign in / Sign up

Export Citation Format

Share Document