Assessing a conceptual model of over-the-counter medication misuse, adverse drug events and health-related quality of life in an elderly population

2015 ◽  
Vol 16 (1) ◽  
pp. 103-110 ◽  
Author(s):  
Shivani K Mhatre ◽  
Sujit S Sansgiry
2008 ◽  
Vol 24 (6) ◽  
pp. 323-329 ◽  
Author(s):  
Sujit S Sansgiry ◽  
Elizabeth Ajuoga ◽  
Caroline Ngo ◽  
Rosa F Yeh

Background: Over-the-counter (OTC) medication use has increased among HIV-infected patients. Inappropriate use of OTC drugs may increase the risk of potential adverse drug events (ADEs), thus decreasing health-related quality of life (HRQL). Objective: To examine the effect of OTC medication misuse and associated ADEs on HRQL of HIV-infected patients. Methods: A cross-sectional field study with HIV-infected patients from an HIV clinic in Houston, Texas, was conducted from April 1, 2005, to June 30, 2005. A validated questionnaire (including questions on OTC medications used; ADEs experienced; and HRQL, Short Form-12, version 2 scale) was administered using self-administered and personal interview techniques. Cronbach's α was estimated to evaluate internal consistency for HRQL scores and χ2 and t-test analyses were performed to evaluate the effect of OTC misuse on ADEs and on HRQL. Results: Of the 215 respondents, 80 (37.2%) misused OTC medications. Thirty-six participants (16.7%) experienced ADEs due to OTC use or misuse. ADE incidence was significantly higher in patients misusing OTCs. Significantly lower HRQL scores for the physical component summary score domains were observed in patients reporting ADEs versus those who did not. Conclusions: HIV-infected patients had lower HRQL scores when they experienced an OTC-associated ADE. Patients misusing OTC medications had a higher incidence of associated ADEs. Interventions by healthcare providers and patients aimed at reducing misuse and ADEs due to OTC medications would improve care and the quality of life for HIV-infected patients.


Gerodontology ◽  
2018 ◽  
Vol 36 (1) ◽  
pp. 71-77 ◽  
Author(s):  
Cristiane da Mata ◽  
Patrick Finbar Allen ◽  
Gerald John McKenna ◽  
Martina Hayes ◽  
Ali Kashan

2016 ◽  
Vol 5 (2) ◽  
pp. 35-42
Author(s):  
Thant Zin ◽  
Than Myint ◽  
Daw KS Naing ◽  
Kyaw Htay ◽  
Aye Aye Wynn ◽  
...  

Ageing is a global phenomenon. In Malaysia, a projected model estimated that the number of elderly would be 3.4 million in 2020 which is more than 10% of the population. A cross-sectional study targeted the elderly population of three villages in rural Sabah, Malaysia aimed to investigate the health-related quality of life, comorbidity, and the socio-demographic profile amongst the elderly in the community. Participants (60 years and above) were selected for face-to-face interviews using health-related quality of life questionnaires (SF-36). SPSS 21 was used for statistical analyses. Results showed that mean (sd) of age; 67.71 (6.95) years. Five common co-morbidities were hypertension (67%), bone and joint pain (63%), gastric pain (67%), poor vision (58%), and hearing problems (33%). The highest HRQoL score was social functioning (67.96) whereas the lowest HRQoL score is role limitation due to emotional problems (30.54). There is a significant relationship between HRQoL domains and socio-demographic factors (gender, marital status, membership in association), and health condition (co-morbidities and access to healthcare, bone and joint pain or arthritis and treatment, hearing impairment and treatment) which indicated need for health and social support like participating in association and access to health care for rural elderly in future programme. We recommend a further study to compare elderly HRQoL in rural, urban and institutional settings for future health-care planning.South East Asia Journal of Public Health Vol.5(2) 2015: 35-42


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