Mini-Mental State Examination subscores indicate visuomotor deficits in Alzheimer's disease patients: A cross-sectional study in a Dutch population

2013 ◽  
Vol 14 (4) ◽  
pp. 880-885 ◽  
Author(s):  
Casper de Boer ◽  
Francesco Mattace-Raso ◽  
Johannes van der Steen ◽  
Johan JM Pel
2017 ◽  
Vol 13 (7S_Part_17) ◽  
pp. P843-P844
Author(s):  
Julius S. Ngwa ◽  
Sharlene Leong ◽  
Lennox A. Graham ◽  
Oyonumo Ntekim ◽  
Joanne S. Allard ◽  
...  

Author(s):  
Sachin Desai ◽  
Chandra S. Metgud

Background: The population of elderly is on the rise with estimates of 8.8%in urban area. Increase in the number of nuclear families, specially in the urban areas the elderly have been experiencing multiple morbidities, predominantly dementia and the burden associated with the caregivers of such elderly is enormous. Thus the study was undertaken to assess the burden of the caregivers of cognitively impaired elderly, residing in an urban area. Methods: It was a Cross sectional study in an Urban Health Centre, field practice area, of JN Medical College, KLE University, Belagavi of North Karnataka from 1st January to 31st December 2012. Among the 783 elderly, >60 years, assessed for cognitive impairment using Mini Mental State Examination/Hindi Mini Mental State Examination for literate /illiterate respectively, 55 elderly were cognitively impaired (MMSE/HMSE score<25). Caregivers of these 55 elderly who were permanent residents of the field practice area (Residing for one year with demented elderly) were interviewed using Zarit Caregiver Burden Scale(ZBI) to assess for emotional, financial, social burnout. Results: 22 (40.00%) Caregivers were males and 33 (60.00%) were females.07(12.73%) had studied up to primary school, 15 (27.27%) up to high school, 24 (43.64%) up to Pre-university degree 01(1.81%) had completed diploma and 8(14.55%) caregivers were graduates. 16 (29.09%) of them had a ZBI scale score between 21 to 40 (mild to moderate burden), 38 (69.09%) scored between 41 to 60 (Moderate to severe burden) and 1 (1.82%) scored between 61-88 and experienced severe burden. Conclusions: Majority 60.0% of the caregivers were women in the productive age group of 21-40 years. Had to take the dual responsibility of care-taking and working plus raising up their children. The caregivers of cognitively impaired elderly, majority of them experienced a lot of physical, emotional, psychological stress and strain. Maximum of the caregivers were over taxed with responsibilities and felt that all responsibility fell on one caregiver (dependence burden). 


2012 ◽  
Vol 153 (12) ◽  
pp. 461-466 ◽  
Author(s):  
Magdolna Pákáski ◽  
Gergely Drótos ◽  
Zoltán Janka ◽  
János Kálmán

The cognitive subscale of the Alzheimer’s Disease Assessment Scale is the most widely used test in the diagnostic and research work of Alzheimer’s disease. Aims: The aim of this study was to validate and investigate reliability of the Hungarian version of the Alzheimer’s Disease Assessment Scale in patients with Alzheimer’s disease and healthy control subjects. Methods: syxty-six patients with mild and moderate Alzheimer’s disease and 47 non-demented control subjects were recruited for the study. The cognitive status was established by the Hungarian version of the Alzheimer’s Disease Assessment Scale and Mini Mental State Examination. Discriminative validity, the relation between age and education and Alzheimer’s Disease Assessment Scale, and the sensitivity and specificity of the test were determined. Results: Both the Mini Mental State Examination and the Alzheimer’s Disease Assessment Scale had significant potential in differentiating between patients with mild and moderate stages of Alzheimer’s disease and control subjects. A very strong negative correlation was established between the scores of the Mini Mental State Examination and the Alzheimer’s Disease Assessment Scale in the Alzheimer’s disease group. The Alzheimer’s Disease Assessment Scale showed slightly negative relationship between education and cognitive performance, whereas a positive correlation between age and Alzheimer’s Disease Assessment Scale scores was detected only in the control group. According to the analysis of the ROC curve, the values of sensitivity and specificity of the Alzheimer’s Disease Assessment Scale were high. Conclusions: The Hungarian version of the Alzheimer’s Disease Assessment Scale was found to be highly reliable and valid and, therefore, the application of this scale can be recommended for the establishment of the clinical stage and follow-up of patients with Alzheimer’s disease. However, the current Hungarian version of the Alzheimer’s Disease Assessment Scale is not sufficient; the list of words and linguistic elements should be selected according to the Hungarian standard in the future. Orv. Hetil., 2012, 153, 461–466.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Manee Pinyopornpanish ◽  
Kanokporn Pinyopornpanish ◽  
Atiwat Soontornpun ◽  
Surat Tanprawate ◽  
Angkana Nadsasarn ◽  
...  

Abstract Background Caregiver burden affects the caregiver’s health and is related to the quality of care received by patients. This study aimed to determine the extent to which caregivers feel burdened when caring for patients with Alzheimer’s Disease (AD) and to investigate the predictors for caregiving burden. Methods A cross-sectional study was conducted. One hundred two caregivers of patients with AD at Maharaj Nakorn Chiang Mai Hospital, a tertiary care hospital, were recruited. Assessment tools included the perceived stress scale (stress), PHQ-9 (depressive symptoms), Zarit Burden Interview-12 (burden), Clinical Dementia Rating (disease severity), Neuropsychiatric Inventory Questionnaires (neuropsychiatric symptoms), and Barthel Activities Daily Living Index (dependency). The mediation analysis model was used to determine any associations. Results A higher level of severity of neuropsychiatric symptoms (r = 0.37, p < 0.01), higher level of perceived stress (r = 0.57, p < 0.01), and higher level of depressive symptoms (r = 0.54, p < 0.01) were related to a higher level of caregiver burden. The direct effect of neuropsychiatric symptoms on caregiver burden was fully mediated by perceived stress and depressive symptoms (r = 0.13, p = 0.177), rendering an increase of 46% of variance in caregiver burden by this parallel mediation model. The significant indirect effect of neuropsychiatric symptoms by these two mediators was (r = 0.21, p = 0.001). Conclusion Caregiver burden is associated with patients’ neuropsychiatric symptoms indirectly through the caregiver’s depressive symptoms and perception of stress. Early detection and provision of appropriate interventions and skills to manage stress and depression could be useful in reducing and preventing caregiver burden.


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