scholarly journals Oral bisphosphonates: Adverse effects on the oral mucosa not related to the jaw bones. A scoping review

Gerodontology ◽  
2021 ◽  
Author(s):  
Christina Psimma ◽  
Zoi Psimma ◽  
Hanna C. Willems ◽  
Wim J. Klüter ◽  
Claar D. Maarel‐Wierink
Keyword(s):  
Adverse Effects ◽  
Oral Mucosa ◽  
Scoping Review ◽  
Oral Bisphosphonates ◽  
Jaw Bones

scholarly journals Adverse Effects of Personal Protective Equipment Among Intensive Care Unit Healthcare Professionals During the COVID-19 Pandemic: A Scoping Review

2021 ◽  
Vol 7 ◽  
pp. 237796082110261
Author(s):  
Takeshi Unoki ◽  
Hideaki Sakuramoto ◽  
Ryuhei Sato ◽  
Akira Ouchi ◽  
Tomoki Kuribara ◽  
...  
Keyword(s):  
Intensive Care ◽  
Adverse Effects ◽  
Scoping Review ◽  
Personal Protective Equipment ◽  
Healthcare Professionals ◽  
World Health ◽  
Protective Equipment ◽  
Medical Database ◽  
Publication Type ◽  
Skin Injuries

Introduction To avoid exposure to SARS-COV-2, healthcare professionals use personal protective equipment (PPE) while treating COVID-19 patients. Prior studies have revealed the adverse effects (AEs) of PPE on healthcare workers (HCWs); however, no review has focused on the AEs of PPE on HCWs in intensive care units (ICUs). This review aimed to identify the AEs of PPE on HCWs working in ICUs during the COVID-19 pandemic. Methods A scoping review was conducted. MEDLINE, CINAHL, the World Health Organization (WHO) global literature on COVID-19, and Igaku-chuo-zasshi (a Japanese medical database), Google Scholar, medRxiv, and Health Research Board (HRB) open research were searched from January 25–28, 2021. The extracted data included author(s) name, year of publication, country, language, article title, journal name, publication type, study methodology, population, outcome, and key findings. Results The initial search identified 691 articles and abstracts. Twenty-five articles were included in the analysis. The analysis comprised four key topics: studies focusing on PPE-related headache, voice disorders, skin manifestations, and miscellaneous AEs of PPE. The majority of AEs for HCWs in ICUs were induced by prolonged use of masks. Conclusion The AEs of PPE among HCWs in ICUs included heat, headaches, skin injuries, chest discomfort, and dyspnea. Studies with a focus on specific diseases were on skin injuries. Moreover, many AEs were induced by prolonged use of masks.

scholarly journals Clinical benefits and adverse effects of siwak (S. persica) use on periodontal health: a scoping review of literature

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Haslinda Ramli ◽  
Tuti Ningseh Mohd-Dom ◽  
Shahida Mohd-Said
Keyword(s):  
Adverse Effects ◽  
Scoping Review ◽  
Oral Hygiene ◽  
English Language ◽  
Final Analysis ◽  
Clinical Effectiveness ◽  
Periodontal Health ◽  
Clinical Attachment Loss ◽  
Tooth Cleaning ◽  
Wide Range

Abstract Background Siwak is a chewing stick used as an oral hygiene aid associated with Muslim communities across the globe since more than 1500 years ago. Used either exclusively or in conjunction with a regular toothbrush, there is evidence supporting its clinical effectiveness in plaque control, but adverse effects on periodontal health remains inconclusive. Objective This study aims to systematically review the wide range of data and literatures related to siwak practice and its effect on periodontal health. Method The review was conducted based on scoping review techniques, searching literature in EBSCOHOST, PubMed, SCOPUS and Google scholar databases using the following search terms: “siwak’ or ‘miswak’ or ‘chewing stick” for intervention, and “periodontium or ‘periodontal’ or ‘periodontal health’ or ‘periodontal disease” for outcome. Articles published between January 1990 to March 2021 and written in English language were included. Results A total of 721 articles collected from the search and 21 of them were eligible for the final analysis. Results of this study was described based on clinical and antibacterial reporting of siwak, method of siwak practice and its adverse effect on oral health. Siwak was found effective at removing dental plaque and improving periodontal health over time although its effect on subgingival microbiota was inconclusive. Presence of gingival recession and clinical attachment loss were much more commonly reported in siwak users, attributable to variations in the methods employed for tooth cleaning using the siwak. Conclusion There is substantial evidence that the lack of standardised reporting for effective siwak use may have resulted in contradictory findings about its oral hygiene benefits and adverse effects. As such, future work on safe and effective siwak practice is to be advocated among its users.

Antimicrobial use at the end of life: a scoping review

2020 ◽  
pp. bmjspcare-2020-002558
Author(s):  
Jack Fairweather ◽  
Lesley Cooper ◽  
Jacqueline Sneddon ◽  
R Andrew Seaton
Keyword(s):  
Antimicrobial Resistance ◽  
Adverse Effects ◽  
End Of Life ◽  
Scoping Review ◽  
Antibiotic Use ◽  
Prescribing Patterns ◽  
Cochrane Library ◽  
Antibiotic Prescribing ◽  
Ovid Medline ◽  
Tract Infections

ObjectiveTo examine antibiotic use in patients approaching end of life, in terms of frequency of prescription, aim of treatment, beneficial and adverse effects and contribution to the development of antimicrobial resistance.DesignScoping reviewData sourcesAn information scientist searched Ovid MEDLINE, Ovid EMBASE, The Cochrane library, PubMed Clinical Queries, NHS Evidence, Epistemonikos, SIGN, NICE, Google Scholar from inception to February 2019 for any study design including, but not limited to, randomised clinical trials, prospective interventional or observational studies, retrospective studies and qualitative studies. The search of Ovid MEDLINE was updated on the 10 June 2020.Study selectionStudies reporting antibiotic use in patients approaching end of life in any setting and clinicians’ attitudes and behaviour in relation to antibiotic prescribing in this populationData extractionTwo reviewers screened studies for eligibility; two reviewers extracted data from included studies. Data were analysed to describe antibiotic prescribing patterns across different patient populations, the benefits and adverse effects (for individual patients and wider society), the rationale for decision making and clinicians behaviours and attitudes to treatment with antibiotics in this patient group.ResultsEighty-eight studies were included. Definition of the end of life is highly variable as is use of antibiotics in patients approaching end of life. Prescribing decisions are influenced by patient age, primary diagnosis, care setting and therapy goals, although patients’ preferences are not always documented or adhered to. Urinary and lower respiratory tract infections are the most commonly reported indications with outcomes in terms of symptom control and survival variably reported. Small numbers of studies reported on adverse events and antimicrobial resistance. Clinicians sometimes feel uncomfortable discussing antibiotic treatment at end of life and would benefit from guidelines to direct care.ConclusionsUse of antibiotics in patients approaching the end of life is common although there is significant variation in practice. There are a myriad of intertwined biological, ethical, social, medicolegal and clinical issues associated with the topic.

scholarly journals A Comprehensive Evaluation of Studies on the Adverse Effects of Medications in Australian Aged care Facilities: A Scoping Review

Pharmacy ◽  
2020 ◽  
Vol 8 (2) ◽  
pp. 56
Author(s):  
Haider Qasim ◽  
Maree Simpson ◽  
Yann Guisard ◽  
Barbora de Courten
Keyword(s):  
Adverse Effects ◽  
Older People ◽  
Scoping Review ◽  
Adverse Drug Events ◽  
Assessment Tool ◽  
The Elderly ◽  
Aged Care ◽  
Inclusion Criteria ◽  
Care Facilities ◽  
Aged Care Facilities

Aim: this scoping review was designed to identify studies that assess adverse drug reactions (ADRs) for older people in Australian aged care facilities. This review critically evaluates each published study to identify the risk of, or actual, adverse drug events in older people. Inclusion criteria: this review considered any clinical studies that examined the adverse effects of medications in older people who were living in aged care facilities. This review considered qualitative studies, analytical studies, randomized controlled trials (RCTs), descriptive cross-sectional studies, and analytic observational studies that explored the use of medications and their adverse effects on older people in clinical settings (including aged care facilities). Methods: an initial search of the PubMed (United State National Library of Medicine), OvidSP, EBSCOHost, ScienceDirect, Wiley Online, SAGE, and SCOPUS databases, with full text was performed, followed by an analysis of the article’s title and abstract. Additionally, MeSH (Medical Subject Headings) was used to describe the article. The initial round of the database search was based on inclusion criteria from studies that assessed tools or protocols aiming to identify the adverse effects of medications on the elderly population suffering chronic conditions or multiple co-morbidities. Two reviewers screened the retrieved papers for inclusion. The data presented in this review are in tabular forms and accompanied by a narrative summary which aligns with the review’s objectives. Results: seven studies were identified, and the extracted data from these studies were grouped according their characteristics and the auditing results of each study. Conclusion: it would be beneficial to design a comprehensive or broadly adverse drug reaction assessment tool derived from Australian data that has been used on the elderly in an Australian healthcare setting.

scholarly journals Cooling of the oral mucosa to prevent adverse effects of chemotherapeutic agents: An in vitro study

2018 ◽  
Vol 47 (5) ◽  
pp. 477-483 ◽  
Author(s):  
Java Walladbegi ◽  
Sarah A. Smith ◽  
Amy K. Grayson ◽  
Craig Murdoch ◽  
Mats Jontell ◽  
...  
Keyword(s):  
Adverse Effects ◽  
Oral Mucosa ◽  
In Vitro Study ◽  
Chemotherapeutic Agents ◽  
Vitro Study

PEPPERMINT OIL, ITS USEFUL, AND ADVERSE EFFECTS ON HUMAN HEALTH: A REVIEW

2020 ◽  
pp. 1-4
Author(s):  
NAGEENA SHABBIR ◽  
SYEDA MONA HASSAN ◽  
SHAHZAD SHARIF MUGHAL ◽  
SUMAIRA PERVEIZ ◽  
MUNEEZA MUNIR ◽  
...  
Keyword(s):  
Adverse Effects ◽  
Respiratory Tract ◽  
Human Health ◽  
Oral Mucosa ◽  
Large Intestine ◽  
Well Being ◽  
Mentha Piperita ◽  
Peppermint Oil

Fundamental oil of Mentha piperita are perplexing blends detached from sweet-smelling plants which may have antimicrobial, cooling receptor trigger, pesticidal, anticancer, hack, asthma, and use in painkiller, exercises of enthusiasm for the sustenance and corrective enterprises just as in the human well-being field in pharmaceutical. According to the German Commission E monographs, peppermint oil is greatly employed as an antispasmodic in the stomach and intestine in bile channel and for the treatment of peevish entrails disorder, inflammation of the respiratory tract, and aggravation of the oral mucosa. Remotely, M. piperita has been employed for myalgia and neuralgia. As indicated by German Commission E, M. piperita may likewise go about as a carminative, disinfectant, and pectolytic, having soothing activity. Enteric-covered peppermint oil containers (Colpermin) are mostly employed as an orally controlled antispasmodic premedication in the study of large intestine.

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