Clinical evaluation of the periodontal health condition and oral health awareness in Parkinson's disease patients

Gerodontology ◽  
2013 ◽  
Vol 32 (2) ◽  
pp. 100-106 ◽  
Author(s):  
Avani R. Pradeep ◽  
Sonender P. Singh ◽  
Santosh S. Martande ◽  
Arjun P. Raju ◽  
Tagya Rustagi ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Oral Health ◽  
Clinical Evaluation ◽  
Health Condition ◽  
Health Awareness ◽  
Periodontal Health

scholarly journals Oral Factors That Impact the Oral Microbiota in Parkinson’s Disease

2021 ◽  
Vol 9 (8) ◽  
pp. 1616
Author(s):  
Natalia S. Rozas ◽  
Gena D. Tribble ◽  
Cameron B. Jeter
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Oral Health ◽  
Soft Tissue ◽  
Oral Hygiene ◽  
Beta Diversity ◽  
Oral Microbiota ◽  
Healthy Controls ◽  
Microbiota Composition ◽  
Salivary Ph

Patients with Parkinson’s disease (PD) are at increased risk of aspiration pneumonia, their primary cause of death. Their oral microbiota differs from healthy controls, exacerbating this risk. Our goal was to explore if poor oral health, poor oral hygiene, and dysphagia status affect the oral microbiota composition of these patients. In this cross-sectional case-control study, the oral microbiota from hard and soft tissues of patients with PD (n = 30) and age-, gender-, and education-matched healthy controls (n = 30) was compared using 16S rRNA gene sequencing for bacterial identification. Study participants completed dietary, oral hygiene, drooling, and dysphagia questionnaires, and an oral health screening. Significant differences in soft tissue beta-diversity (p < 0.005) were found, and a higher abundance of opportunistic oral pathogens was detected in patients with PD. Factors that significantly influenced soft tissue beta-diversity and microbiota composition include dysphagia, drooling (both p < 0.05), and salivary pH (p < 0.005). Thus, patients with PD show significant differences in their oral microbiota compared to the controls, which may be due, in part, to dysphagia, drooling, and salivary pH. Understanding factors that alter their oral microbiota could lead to the development of diagnostic and treatment strategies that improve the quality of life and survivability of these patients.

Understanding the impact of Parkinson's disease on oral health

2021 ◽  
Vol 17 (4) ◽  
pp. 184-187
Author(s):  
Beverley Moorhouse
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Oral Health ◽  
The Impact

Beverley Moorhouse explores the difficulties some individuals may face and the impact the disease has on the ability to maintain effective oral health

scholarly journals Oral Health of Patients with Parkinson's Disease: Factors Related to Their Better Dental Status

2003 ◽  
Vol 201 (3) ◽  
pp. 171-179 ◽  
Author(s):  
Shingo Fukayo ◽  
Koichi Nonaka ◽  
Teruo Shimizu ◽  
Eiji Yano
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Oral Health ◽  
Dental Status

scholarly journals Autologous Adrenal Medullary, Fetal Mesencephalic, and Fetal Adrenal Brain Transplantation in Parkinson's Disease: A Long-Term Postoperative Follow-Up

1991 ◽  
Vol 2 (3-4) ◽  
pp. 157-164 ◽  
Author(s):  
Ignacio Madrazo ◽  
Rebecca Franco-Bourland ◽  
Maricarmen Aguilera ◽  
Feggy Ostrosky-Solis ◽  
Mario Madrazo ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Clinical Evaluation ◽  
Clinical Status ◽  
Substantial Improvement ◽  
Neuropsychological Changes ◽  
Postural Imbalance ◽  
Tissue Grafts ◽  
Gait Disturbances

We report on the clinical status of 5 patients with Parkinson's disease (PD) 3 years after autologous adrenal medullary (AM)-to-caudate nucleus (CN) implanfion, and of 2 PD patients, 2 years after fetal ventral mesencephalon (VM)- and fetal adrenal (A)-to-CN homotransplantation. Current clinical evaluation of 4 of the AM grafted patients revealed sustained bilateral amelioration of their PD signs, most notably of rgidity, postural imbalance and gait disturbances, resulting in a substantial improvement in their quality of life. the disease-related dystonia of one of them disappeared only 2 years after surgery. The levodopa requirements of 2 of these patients and the anticholinergic therapy of another have been reduced. In agreement with the satisfactory clinical evaluation of these 4 patients, their neuropsychological and electrophysiological improvements, initially registered 3 months after surgery, have been maintained for 3 years. After 1 year of significant recovery, the 5th patient of this group has almost returned to her preoperative state.The 2 homotransplanted patients also showed sustained bilateral improvement of their PD signs. Two years after surgery, the most improved signs of the fetal VM case were rigidity, bradykinesia, postural imbalance, gait disturbances and facial expression. The fetal A case has only shown amelioration of rigidity and bradykinesia. Neither of them has shown significant neuropsychological changes. Their current levodopa requirements are less than before surgery.The improvements shown here by PD patients after brain tissue grafts go beyond those obtained using any other therapeutic approach, when levodopa fails. Although more studies and the development of these procedures are obviously required, these initial human trials appear to be resisting the test of time.

Pharmacokinetic and clinical evaluation of liquid L-dopa/carbidopa in Parkinson's disease

1998 ◽  
Vol 5 (2) ◽  
pp. 178-181
Author(s):  
J Marriott ◽  
B Bryant ◽  
P Kempster ◽  
M Shif ◽  
M.McD Lewis ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Clinical Evaluation
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