scholarly journals Control of sucrose accumulation in sugarcane ( Saccharum spp . hybrids) involves miRNA‐mediated regulation of genes and transcription factors associated with sugar metabolism

GCB Bioenergy ◽  
2021 ◽  
Author(s):  
Miao Wang ◽  
Ao‐Mei Li ◽  
Fen Liao ◽  
Cui‐Xian Qin ◽  
Zhong‐Liang Chen ◽  
...  
Keyword(s):  
Transcription Factors ◽  
Sugar Metabolism ◽  
Sucrose Accumulation ◽  
Saccharum Spp ◽  
Factors Associated

scholarly journals Identification of proteins and metabolic networks associated with sucrose accumulation in sugarcane (Saccharum spp. interspecific hybrids)

2021 ◽  
Vol 16 (1) ◽  
pp. 166-178
Author(s):  
Cui-Xian Qin ◽  
Zhong-Liang Chen ◽  
Miao Wang ◽  
Ao-Mei Li ◽  
Fen Liao ◽  
...  
Keyword(s):  
Interspecific Hybrids ◽  
Metabolic Networks ◽  
Sucrose Accumulation ◽  
Saccharum Spp

Identification of transcription factors associated with castration-resistance: Is the serum responsive factor a potential therapeutic target?

The Prostate ◽  
2013 ◽  
Vol 73 (7) ◽  
pp. 743-753 ◽  
Author(s):  
Maria Prencipe ◽  
Stephen F. Madden ◽  
Amanda O'Neill ◽  
Gillian O'Hurley ◽  
Aedin Culhane ◽  
...  
Keyword(s):  
Transcription Factors ◽  
Therapeutic Target ◽  
Castration Resistance ◽  
Potential Therapeutic Target ◽  
Factors Associated

scholarly journals How cancer cells remodel lipid metabolism: strategies targeting transcription factors

2021 ◽  
Vol 20 (1) ◽  
Author(s):  
Do-Won Jeong ◽  
Seulbee Lee ◽  
Yang-Sook Chun
Keyword(s):  
Transcription Factor ◽  
Transcription Factors ◽  
Lipid Metabolism ◽  
Cancer Cells ◽  
Cancer Biology ◽  
Factors Associated ◽  
Modeling Techniques ◽  
Related Enzyme ◽  
Potential Strategy

AbstractReprogramming of lipid metabolism has received increasing recognition as a hallmark of cancer cells because lipid dysregulation and the alteration of related enzyme profiles are closely correlated with oncogenic signals and malignant phenotypes, such as metastasis and therapeutic resistance. In this review, we describe recent findings that support the importance of lipids, as well as the transcription factors involved in cancer lipid metabolism. With recent advances in transcription factor analysis, including computer-modeling techniques, transcription factors are emerging as central players in cancer biology. Considering the limited number and the crucial role of transcription factors associated with lipid rewiring in cancers, transcription factor targeting is a promising potential strategy for cancer therapy.

scholarly journals Traumatic glioblastoma: commentary and suggested mechanism

2018 ◽  
Vol 46 (6) ◽  
pp. 2170-2176
Author(s):  
Nissim Ohana ◽  
Daniel Benharroch ◽  
Dimitri Sheinis ◽  
Abraham Cohen
Keyword(s):  
Traumatic Brain Injury ◽  
Transcription Factors ◽  
Brain Injury ◽  
Brain Injuries ◽  
Hypoxia Inducible Factor ◽  
Subsequent Development ◽  
Factors Associated ◽  
The Relationship

The role of head trauma in the development of glioblastoma is highly controversial and has been minimized since first put forward. This is not unexpected because skull injuries are overwhelmingly more common than glioblastoma. This paper presents a commentary based on the contributions of James Ewing, who established a major set of criteria for the recognition of an official relationship between trauma and cancer. Ewing’s criteria were very stringent. The scholars who succeeded Ewing have facilitated the characterization of traumatic brain injuries since the introduction of computed tomography and magnetic resonance imaging. Discussions of the various criteria that have since developed are now being conducted, and those of an unnecessarily limiting nature are being highlighted. Three transcription factors associated with traumatic brain injury have been identified: p53, hypoxia-inducible factor-1α, and c-MYC. A role for these three transcription factors in the relationship between traumatic brain injury and glioblastoma is suggested; this role may support a cause-and-effect link with the subsequent development of glioblastoma.

Reprogramming to help the old see like the young

2020 ◽  
Vol 12 (574) ◽  
pp. eabf7738
Author(s):  
Carlos A. Aguilar
Keyword(s):  
Transcription Factors ◽  
Retinal Ganglion Cells ◽  
Ganglion Cells ◽  
Aged Mouse ◽  
Retinal Ganglion ◽  
Functional Characteristics ◽  
Factors Associated

Transcription factors associated with pluripotency restore molecular and functional characteristics resembling youth in aged mouse retinal ganglion cells.

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