scholarly journals Functional conservation of MBD proteins: MeCP2 andDrosophilaMBD proteins alter sleep

2016 ◽  
Vol 15 (8) ◽  
pp. 757-774 ◽  
Author(s):  
T. Gupta ◽  
H. R. Morgan ◽  
J. A. Bailey ◽  
S. J. Certel
Keyword(s):  
Functional Conservation ◽  
Mbd Proteins

scholarly journals Overexpression of a methyl-CpG-binding protein gene OsMBD707 leads to larger tiller angles and reduced photoperiod sensitivity in rice

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Mengyu Qu ◽  
Zhujian Zhang ◽  
Tingmin Liang ◽  
Peipei Niu ◽  
Mingji Wu ◽  
...  
Keyword(s):  
Expression Patterns ◽  
Photoperiod Sensitivity ◽  
Rna Seq ◽  
Active Expression ◽  
Binding Protein Gene ◽  
Flowering Regulator ◽  
Regulator Genes ◽  
Mbd Protein ◽  
Delayed Flowering ◽  
Mbd Proteins

Abstract Background Methyl-CpG-binding domain (MBD) proteins play important roles in epigenetic gene regulation, and have diverse molecular, cellular, and biological functions in plants. MBD proteins have been functionally characterized in various plant species, including Arabidopsis, wheat, maize, and tomato. In rice, 17 sequences were bioinformatically predicted as putative MBD proteins. However, very little is known regarding the function of MBD proteins in rice. Results We explored the expression patterns of the rice OsMBD family genes and identified 13 OsMBDs with active expression in various rice tissues. We further characterized the function of a rice class I MBD protein OsMBD707, and demonstrated that OsMBD707 is constitutively expressed and localized in the nucleus. Transgenic rice overexpressing OsMBD707 displayed larger tiller angles and reduced photoperiod sensitivity—delayed flowering under short day (SD) and early flowering under long day (LD). RNA-seq analysis revealed that overexpression of OsMBD707 led to reduced photoperiod sensitivity in rice and to expression changes in flowering regulator genes in the Ehd1-Hd3a/RFT1 pathway. Conclusion The results of this study suggested that OsMBD707 plays important roles in rice growth and development, and should lead to further studies on the functions of OsMBD proteins in growth, development, or other molecular, cellular, and biological processes in rice.

scholarly journals Functional conservation and coherence of HIV-1 subtype A Vpu alleles

2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Bizhan Romani ◽  
Amirarsalan Kavyanifard ◽  
Elham Allahbakhshi
Keyword(s):  
Functional Conservation ◽  
Subtype A ◽  
Hiv 1

scholarly journals IRF7 in the Australian Black Flying Fox, Pteropus alecto: Evidence for a Unique Expression Pattern and Functional Conservation

PLoS ONE ◽  
2014 ◽  
Vol 9 (8) ◽  
pp. e103875 ◽  
Author(s):  
Peng Zhou ◽  
Chris Cowled ◽  
Ashley Mansell ◽  
Paul Monaghan ◽  
Diane Green ◽  
...  
Keyword(s):  
Expression Pattern ◽  
Functional Conservation ◽  
Unique Expression Pattern ◽  
Flying Fox

scholarly journals Structural and functional conservation of key domains in InsP3 and ryanodine receptors

Nature ◽  
2012 ◽  
Vol 483 (7387) ◽  
pp. 108-112 ◽  
Author(s):  
Min-Duk Seo ◽  
Saroj Velamakanni ◽  
Noboru Ishiyama ◽  
Peter B. Stathopulos ◽  
Ana M. Rossi ◽  
...  
Keyword(s):  
Ryanodine Receptors ◽  
Functional Conservation

A view of partial laryngectomy in the treatment of laryngeal cancer

1987 ◽  
Vol 101 (2) ◽  
pp. 143-154 ◽  
Author(s):  
H. J. Shaw
Keyword(s):  
Laryngeal Cancer ◽  
Glottic Cancer ◽  
Partial Laryngectomy ◽  
Therapeutic Dosage ◽  
Reasonable Expectation ◽  
Functional Conservation ◽  
Supraglottic Cancer ◽  
Results Of Treatment ◽  
The United Kingdom ◽  
Conservation Surgery

AbstractAttention is drawn to the problems of surgical resection by partial laryngectomy after full therapeutic dosage of telecobalt irradiation. Material is presented from two treatment centres to indicate trends in surgical treatment and the complications experienced. Results will be given which confirm a reasonable expectation of cure and functional conservation by vertical partial laryngectomy for recurrence of glottic cancer after irradiation. The results of treatment of recurrent supraglottic cancer by horizontal partial laryngectomy gave more cause for concern in terms of complications and survival. In conclusion an attempt is made, based on the quoted experience, to define the position of conservation surgery in two centres for laryngeal cancer in the United Kingdom.

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