Toll-like receptor 2 antagonists identified through virtual screening and experimental validation

Prasannavenkatesh Durai; Hyeon-Jun Shin; Asma Achek; Hyuk-Kwon Kwon; Rajiv Gandhi Govindaraj; Suresh Panneerselvam; Dhanusha Yesudhas; Jiwon Choi; Kyoung Tai No; Sangdun Choi

doi:10.1111/febs.14124

Toll-like receptor 2 antagonists identified through virtual screening and experimental validation

FEBS Journal ◽

10.1111/febs.14124 ◽

2017 ◽

Vol 284 (14) ◽

pp. 2264-2283 ◽

Cited By ~ 8

Author(s):

Prasannavenkatesh Durai ◽

Hyeon-Jun Shin ◽

Asma Achek ◽

Hyuk-Kwon Kwon ◽

Rajiv Gandhi Govindaraj ◽

...

Keyword(s):

Virtual Screening ◽

Experimental Validation ◽

Toll Like Receptor ◽

Toll Like Receptor 2

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Toll-like receptor 2 signaling is important for fas ligand on NKT cells, may contribute to liver injury induced by Salmonella infection

Gastroenterology ◽

10.1016/s0016-5085(01)81774-1 ◽

2001 ◽

Vol 120 (5) ◽

pp. A357-A357

Author(s):

H SHIMIZU ◽

Y FUKUDA ◽

I NAKANO ◽

Y KATANO ◽

K NAGANO ◽

...

Keyword(s):

Liver Injury ◽

Fas Ligand ◽

Nkt Cells ◽

Toll Like Receptor ◽

Salmonella Infection ◽

Toll Like Receptor 2

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Review for "Kupffer cell activation by different microbial lysates: toll‐like receptor‐2 plays pivotal role on thromboxane A 2 production in mice and humans"

10.1002/eji.201948507/v2/review2 ◽

2020 ◽

Keyword(s):

Kupffer Cell ◽

Cell Activation ◽

Pivotal Role ◽

Toll Like Receptor ◽

Toll Like Receptor 2

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Decision letter for "Kupffer cell activation by different microbial lysates: toll‐like receptor‐2 plays pivotal role on thromboxane A 2 production in mice and humans"

10.1002/eji.201948507/v1/decision1 ◽

2020 ◽

Keyword(s):

Kupffer Cell ◽

Cell Activation ◽

Pivotal Role ◽

Toll Like Receptor ◽

Toll Like Receptor 2

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Hepatitis B virus initiates toll-like receptor 2-dependent immune signaling while entering primary human hepatocytes

Zeitschrift für Gastroenterologie ◽

10.1055/s-0037-1612864 ◽

2018 ◽

Vol 56 (01) ◽

pp. E2-E89

Author(s):

Z Zhang ◽

M Trippler ◽

C Real ◽

M Werner ◽

T Kemper ◽

...

Keyword(s):

Hepatitis B Virus ◽

Hepatitis B ◽

Human Hepatocytes ◽

Toll Like Receptor ◽

Immune Signaling ◽

Primary Human Hepatocytes ◽

B Virus ◽

Toll Like Receptor 2

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Faculty Opinions recommendation of Cutting edge: Immune stimulation by neisserial porins is toll-like receptor 2 and MyD88 dependent.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1005249.60955 ◽

2002 ◽

Author(s):

Jenny Ting

Keyword(s):

Cutting Edge ◽

Immune Stimulation ◽

Toll Like Receptor ◽

Toll Like Receptor 2

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Faculty Opinions recommendation of Hemagglutinin protein of wild-type measles virus activates toll-like receptor 2 signaling.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1009670.132458 ◽

2002 ◽

Author(s):

Lindsey Hutt-Fletcher

Keyword(s):

Measles Virus ◽

Toll Like Receptor ◽

Wild Type ◽

Hemagglutinin Protein ◽

Toll Like Receptor 2

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Faculty Opinions recommendation of Cutting edge: a Toll-like receptor 2 polymorphism that is associated with lepromatous leprosy is unable to mediate mycobacterial signaling.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1011673.191862 ◽

2003 ◽

Author(s):

Giorgio Berton

Keyword(s):

Lepromatous Leprosy ◽

Cutting Edge ◽

Toll Like Receptor ◽

Toll Like Receptor 2

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Faculty Opinions recommendation of Cutting edge: a Toll-like receptor 2 polymorphism that is associated with lepromatous leprosy is unable to mediate mycobacterial signaling.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1011673.186469 ◽

2003 ◽

Author(s):

Ricardo Gazzinelli

Keyword(s):

Lepromatous Leprosy ◽

Cutting Edge ◽

Toll Like Receptor ◽

Toll Like Receptor 2

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Faculty Opinions recommendation of Two lipoproteins extracted from Escherichia coli K-12 LCD25 lipopolysaccharide are the major components responsible for Toll-like receptor 2-mediated signaling.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1011729.182168 ◽

2003 ◽

Author(s):

Elaine Tuomanen

Keyword(s):

Escherichia Coli ◽

Toll Like Receptor ◽

Toll Like Receptor 2 ◽

K 12

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Faculty Opinions recommendation of Yersinia V-antigen exploits toll-like receptor 2 and CD14 for interleukin 10-mediated immunosuppression.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1010308.150257 ◽

2002 ◽

Author(s):

James Bliska

Keyword(s):

Interleukin 10 ◽

Toll Like Receptor ◽

Toll Like Receptor 2 ◽

V Antigen

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