Patterns sought among users of herbal products who developed liver toxicity

2016 ◽  
Vol 21 (3-4) ◽  
pp. 158-159
Author(s):  
S Barrett
Keyword(s):  
Liver Toxicity ◽  
Herbal Products

scholarly journals DNA damage by Withanone as a potential cause of liver toxicity observed for herbal products of Withania somnifera (Ashwagandha)

2021 ◽  
Vol 2 ◽  
pp. 72-81
Author(s):  
Shazia Siddiqui ◽  
Nabeel Ahmed ◽  
Mausumi Goswami ◽  
Anindita Chakrabarty ◽  
Goutam Chowdhury
Keyword(s):  
Dna Damage ◽  
Withania Somnifera ◽  
Liver Toxicity ◽  
Herbal Products

scholarly journals Hepatotoxic Botanicals - An Evidence-based Systematic Review

2013 ◽  
Vol 16 (3) ◽  
pp. 376 ◽  
Author(s):  
Reem J Abdualmjid ◽  
Consolato Sergi
Keyword(s):  
Liver Toxicity ◽  
Healthcare Providers ◽  
Herbal Medicines ◽  
Hepatic Necrosis ◽  
Herbal Remedies ◽  
Cochrane Library ◽  
Herbal Products ◽  
Alternative Medicines ◽  
Natural Medicine ◽  
Elevated Liver Enzymes

Purpose. Herbal medicines have been increasingly used worldwide. However, the potential harms of these herbs have been noticed most recently following hepatotoxicity with ingestion of herbal remedies. The aim of this review is to evaluate the evidence of hepatotoxic effects linked to use of herbal preparations. Method. Electronic search was performed by searching several databases: PubMed, HerbMed, Google Scholar, Scopus, Cochrane Database of Systematic Reviews and Cochrane Library using both Latin and common names of several herbs. Language was restricted to English and articles were selected for relevance reporting incidence of hepatotoxicity associated with use of herbal products in human. Results. From a total of 565 relevant reviews and articles, 254 met our inclusion criteria and were analyzed. Serious hepatotoxic events associated with various herbal products alone or in combination with other drugs have been reported. Linking to herbal constituents the spectrum of liver toxicity includes elevated liver enzymes, acute or chronic hepatitis, cholestasis, hepatic necrosis, fibrosis, and cirrhosis, as well as acute liver failure and hepatic veno-occlusive disease. Conclusion. The hepatotoxicity of herbs was extensively acknowledged. As the use of natural medicine increases, the risk of liver toxicity and drug interaction increase as well. Accordingly, herbal remedies have been known as hepatotoxins causing several liver damages. Further scientific studies with high and good quality are needed to identify toxic compounds and understand the exact mechanism of hepatotoxicity-induced by herbs. The adverse effects of herbal products must be fully reported as well as extensive education of healthcare providers must be provided in order to reduce danger of alternative medicines. This article is open to POST-PUBLICATION REVIEW. Registered readers (see “For Readers”) may comment by clicking on ABSTRACT on the issue’s contents page.

scholarly journals Herbal Supplements and Hepatotoxicity: A Short Review

2015 ◽  
Vol 10 (10) ◽  
pp. 1934578X1501001 ◽  
Author(s):  
Haszianaliza Haslan ◽  
Farihah Haji Suhaimi ◽  
Srijit Das
Keyword(s):  
Liver Toxicity ◽  
Centella Asiatica ◽  
Short Review ◽  
Morinda Citrifolia ◽  
Herbal Remedies ◽  
Xanthium Strumarium ◽  
Herbal Supplements ◽  
Aloe Barbadensis ◽  
Herbal Products ◽  
Medical Practitioners

Herbal products have gained popularity over the past few decades. The reasons attributed to the rise in popularity are cheaper costs, easy availability, patient compliance and fewer side effects. However, liver toxicity following consumption of herbal remedies is on the increase. Thus, there is an urgent need to understand the mechanism of action of the herbal supplements on the liver. Occasionally, herbal supplements may also interact with conventional drugs. The present review focusses on a few herbs such as Aloe barbadensis, Atractylis gummifera, Centella asiatica, Mitragyna speciosa, Morinda citrifolia, Larea tridentata, Symphytum officinale, Teucrium chamaedrys and Xanthium strumarium, which are reported to cause hepatotoxicity in humans and animals. Prior knowledge on hepatotoxicity caused by herbs may be beneficial for clinicians and medical practitioners.

Effects of herbal products in vitro and in vivo

Planta Medica ◽  
2013 ◽  
Vol 79 (13) ◽  
Author(s):  
MJ Groot ◽  
MG Pikkemaat ◽  
WD Driessen van Lankveld
Keyword(s):  
Herbal Products

Hepatoprotective activity of the wild carrot chloroform-based fraction against CCl4-induced liver toxicity in mice

Planta Medica ◽  
2014 ◽  
Vol 80 (16) ◽  
Author(s):  
W Shebaby ◽  
M El-Sibai ◽  
M Mroueh ◽  
K Bodman-Smith ◽  
R Taleb ◽  
...  
Keyword(s):  
Liver Toxicity ◽  
Hepatoprotective Activity ◽  
Wild Carrot

Herba Reudeuep With Modification of Heating In Virgin Cocanut Oil

2020 ◽  
Vol 2 (1) ◽  
Author(s):  
Wahyuzan Wahyuzan ◽  
Lukmanul Hakim ◽  
Rahmat Afrizal ◽  
Asmeri Lamona ◽  
Khairuni Khairuni ◽  
...  
Keyword(s):  
Modern Medicine ◽  
Heating Time ◽  
Agricultural Product ◽  
Average Yield ◽  
Herbal Products ◽  
The Public ◽  
Randomized Design ◽  
Herbal Plants ◽  
Medicinal Properties ◽  
Completely Randomized Design

Traditional medicine in Indonesia has been known by the public before formal health services using modern medicine. Indonesia has many type of herbal plants which have medicinal properties including dadap (Erythrina orientalis). This study aims to utilized dadap herbal liniment by modifying heating in Vigin Cocanut Oil. The study conducted in the laboratory of Agricultural Product Processing using a Factorial Completely Randomized Design (CRD). The first factor is the addition of 250 ml (M1), 375 ml (m2), and 400 ml (M3) Virgin Cocanut Oil treatment. The second factor is the heating tim of 5 minutes (L1), 10 minutes (L2), and 15 minutes (L3). Observation variable consisted of yield, Specific gravity, and organoleptic test of aroma and colored. The result showed an average yield of 87.70-91.88%. The highest yield was found in the treatment of adding 400 ml Virgin Cocanut Oil and 15 minutes of heating time. The highest type of weight was found in the treatment of addition of 325 ml Virgin Cocanut Oil and 5 minutes heating time. Based on the organoleptic scent test, the everage penalist gives a like answer. Organoleptic colors of reudeuep herbal products is according to SNI number 06-23-2006.

Standardization of Some Commercial Anti-diabetic Herbal Products containing Syzygiumcumini

2017 ◽  
Vol 5 (1) ◽  
pp. 21-30
Author(s):  
JASMEEN KAUR ◽  
◽  
MUNISH SINGLA ◽  
BALRAJ SAINI ◽  
GULSHAN BANSAL
Keyword(s):  
Herbal Products
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