Tachykinin antagonists ameliorate surgically induced impairment of gastrointestinal motility in rats

Author(s):  
Artur Umer ◽  
Hanna Ługowska‐Umer ◽  
Oliver Schönborn‐Kellenberger ◽  
Paweł K. Korolkiewicz ◽  
Łukasz Sein‐Anand ◽  
...  
2020 ◽  
Vol 255 ◽  
pp. 510-516
Author(s):  
Artur Umer ◽  
Hanna Ługowska-Umer ◽  
Oliver Schönborn-Kellenberger ◽  
Paweł K. Korolkiewicz ◽  
Łukasz Sein-Anand ◽  
...  

2019 ◽  
Vol 55 (0) ◽  
pp. 23-33
Author(s):  
Hanna Ługowska-Umer ◽  
Artur Umer ◽  
Krzysztof Kuziemski ◽  
Łukasz Sein-Anand ◽  
Roman P. Korolkiewicz

1955 ◽  
Vol 29 (5) ◽  
pp. 789-802 ◽  
Author(s):  
John T. Farrar ◽  
Franz J. Ingelfinger

1951 ◽  
Vol 17 (4) ◽  
pp. 551-559 ◽  
Author(s):  
Michael J. Lepore ◽  
Ross Golden ◽  
Charles A. Flood

2020 ◽  
Vol 158 (6) ◽  
pp. S-1149-S-1150
Author(s):  
Jared T. Winston ◽  
Patricia Guzman Rojas ◽  
Abigail Stocker ◽  
Douglas Lorenz ◽  
Michael W. Daniels ◽  
...  

1955 ◽  
Vol 28 (4) ◽  
pp. 500-509 ◽  
Author(s):  
William P. Chapman ◽  
Stanley M. Wyman ◽  
Jacques O. Gagnon ◽  
John A. Benson ◽  
Chester M. Jones ◽  
...  

2013 ◽  
Vol 74 (S 01) ◽  
Author(s):  
Michael Link ◽  
William Copeland ◽  
Patrick Maloney ◽  
Alejandro Rabinstein

2014 ◽  
Vol 37 (2) ◽  
pp. 85 ◽  
Author(s):  
Ata Topcuoglu ◽  
Mustafa Albayrak ◽  
Hayriye Erman ◽  
Huriye Balci ◽  
Mesut Karakus ◽  
...  

Purpose: The purpose of this study was to analyze the effects of estrogen deficiency and hormone replacement therapy (HRT) on fibrinolytic activity in a rat mode of surgically-induced menopause. Methods: Twelve-week-old, sexually mature female Sprague-Dawley rats, each weighing 200–250 g, were randomly divided into four groups: (1) sham-operated group, (2) ovariectomy group, (3) ovariectomy group followed by oral administration of daily 17β-estradiol (0.02 mg/kg/day) (E2) + norethisterone acetate (0.01 mg/kg/day), and (4) ovariectomy group followed by oral administration of daily 17β-estradiol (0.01 mg/kg/day) + drospirenone (0.02 mg/kg/day). Tissue plasminogen activator (tPA) antigen, plasminogen activator inhibitor-1 (PAI-1) antigen, and PAI-1/tPA levels were measured as markers of fibrinolysis in plasma and liver and brain tissue. Results: Compared with sham-operated rats, ovariectomized rats showed higher levels of fibrinolytic activity; however, the increased fibrinolytic activity in plasma and liver tissue was significantly reduced by HRT regimens. No change was observed in the levels of fibrinolytic activity in brain tissue. Conclusions: HRT showed beneficial effects by decreasing fibrinolytic activity related to surgically-induced menopause. Short-term HRT treatment was associated with a shift in the procoagulant-anticoagulant balance toward a procoagulant state.


2013 ◽  
Vol 63 (1) ◽  
pp. 93-94
Author(s):  
Tetsuro Oono

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