Cannabidiol alleviates hemorrhagic shock‐induced neural apoptosis in rats by inducing autophagy through activation of the PI3K/AKT pathway

2020 ◽  
Vol 34 (6) ◽  
pp. 640-649
Author(s):  
Bo Lin ◽  
Youguang Gao ◽  
Zhiwang Li ◽  
Zhiming Zhang ◽  
Xianzhong Lin ◽  
...  
Keyword(s):  
Hemorrhagic Shock ◽  
Akt Pathway ◽  
Neural Apoptosis

Treatment of ebola and other infectious diseases: melatonin “goes viral”

2020 ◽  
Vol 3 (1) ◽  
pp. 43-57 ◽  
Author(s):  
Russel J Reiter ◽  
Qiang Ma ◽  
Ramaswamy Sharma
Keyword(s):  
Mortality Rate ◽  
Infectious Diseases ◽  
Hemorrhagic Shock ◽  
Safety Profile ◽  
Ebola Virus ◽  
Viral Infections ◽  
Virus Disease ◽  
Attractive Potential ◽  
Potential Treatment

This review summarizes published reports on the utility of melatonin as a treatment for virus-mediated diseases. Of special note are the data related to the role of melatonin in influencing Ebola virus disease. This infection and deadly condition has no effective treatment and the published works documenting the ability of melatonin to attenuate the severity of viral infections generally and Ebola infection specifically are considered. The capacity of melatonin to prevent one of the major complications of an Ebola infection, i.e., the hemorrhagic shock syndrome, which often contributes to the high mortality rate, is noteworthy. Considering the high safety profile of melatonin, the fact that it is easily produced, inexpensive and can be self-administered makes it an attractive potential treatment for Ebola virus pathology.  

Hemorrhagic Shock and Encephalopathy Syndrome: A Case Report

2001 ◽  
Vol 44 (3) ◽  
pp. 385
Author(s):  
Sook Ja Yoon ◽  
Yun Sun Choi ◽  
Chung Ho Shin ◽  
Sung Bum Cho ◽  
Jae Min Cho ◽  
...  
Keyword(s):  
Case Report ◽  
Hemorrhagic Shock
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