Skin atrophy caused by topical glucocorticoids is less common in patients with atopic dermatitis than in those with psoriasis

2021 ◽  
Author(s):  
Chung Hyeok Lee ◽  
Sung Jay Choe ◽  
Dong Hye Kim ◽  
Eun Jung Kim ◽  
Minseob Eom ◽  
...  
2019 ◽  
Vol 139 (9) ◽  
pp. S231
Author(s):  
C. Lee ◽  
S. Choe ◽  
D. Kim ◽  
E. Kim ◽  
S. Hong ◽  
...  

1998 ◽  
Vol 15 (1) ◽  
pp. 7-11 ◽  
Author(s):  
C Heuck ◽  
T Ternowitz ◽  
T Herlin ◽  
OD Wolthers

2009 ◽  
Vol 2 (1) ◽  
pp. 51-55 ◽  
Author(s):  
Toshiyuki Yamamoto

Tacrolimus ointment is an agent approved for the treatment of atopic dermatitis; however, tacrolimus has been expected also as one of the promising therapeutic strategies for other T-cell mediated inflammatory skin disorders. Recent progress have demonstrated that topical tacrolimus shows beneficial effects for psoriasis depending on sites. In particular, facial, intertriginous, and genital psoriasis respond to topical tacrolimus dramatically in a short period. Further, topical tacrolimus is tolerable also for child psoriasis. Because topical tacrolimus does not induce either skin atrophy or telangiectasia different from corticosteroids, it is recommended to be a first choice. The most proper way of topical tacrolimus therapy at present is to use this ointment intermittently after the remission was once obtained, paying attention to its adverse effects.


2004 ◽  
Vol 8 (4) ◽  
pp. 244-247 ◽  
Author(s):  
Aditya K. Gupta ◽  
Melody Chow

Background: Topical steroids have been a popular choice for treating various cutaneous disorders; however, the potential for significant local and systemic adverse events, like skin atrophy and hypothalamic–pituitary–adrenal (HPA) axis suppression, has limited their use. Objective: This article reviews the topical steroid prednicarbate through its mechanism of action, clinical efficacy, and adverse events profile. Methods: Published literature containing the word “prednicarbate” was examined and summarized. Results: Prednicarbate is a nonhalogenated, double-ester derivative of prednisolone that has been used in the treatment of inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses such as atopic dermatitis. It has a favorable benefit–risk ratio, low skin atrophy potential, and high anti-inflammatory action. Conclusion: These characteristics make prednicarbate an ideal alternative agent for children, elderly patients, and those who require long-term intermittent treatment.


2009 ◽  
Vol 15 (1) ◽  
pp. 7-11
Author(s):  
Carsten Heuck ◽  
Thomas Ternowitz ◽  
Troels Herlin ◽  
Ole D. Wolthers

2012 ◽  
Vol 57 (3) ◽  
pp. 296-299 ◽  
Author(s):  
Elisabeth Johnson ◽  
Pamela Groben ◽  
Alisa Eanes ◽  
Priya Iyer ◽  
Joseph Ugoeke ◽  
...  

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