Molecular epidemiology of non‐syndromic autosomal recessive congenital ichthyosis in a Middle‐Eastern population

2021 ◽  
Author(s):  
Janan Mohamad ◽  
Liat Samuelov ◽  
Natalia Malchin ◽  
Tom Rabinowitz ◽  
Sari Assaf ◽  
...  
Keyword(s):  
Molecular Epidemiology ◽  
Autosomal Recessive ◽  
Middle Eastern ◽  
Eastern Population ◽  
Congenital Ichthyosis ◽  
Middle Eastern Population ◽  
Autosomal Recessive Congenital Ichthyosis

scholarly journals Molecular Epidemiology of Hereditary Epidermolysis Bullosa in a Middle Eastern Population

2006 ◽  
Vol 126 (4) ◽  
pp. 777-781 ◽  
Author(s):  
Judeh Abu Sa'd ◽  
Margarita Indelman ◽  
Ellen Pfendner ◽  
Tzipora C. Falik-Zaccai ◽  
Mordechai Mizrachi-Koren ◽  
...  
Keyword(s):  
Molecular Epidemiology ◽  
Epidermolysis Bullosa ◽  
Middle Eastern ◽  
Eastern Population ◽  
Middle Eastern Population ◽  
Hereditary Epidermolysis Bullosa

scholarly journals 073 Molecular epidemiology of epidermolysis bullosa in a Middle Eastern population

2021 ◽  
Vol 141 (10) ◽  
pp. S161
Author(s):  
S. Bergson ◽  
D. Daniely ◽  
D. Bomze ◽  
T. Falik-Zaccai ◽  
E. Avitan-Hersh ◽  
...  
Keyword(s):  
Molecular Epidemiology ◽  
Epidermolysis Bullosa ◽  
Middle Eastern ◽  
Eastern Population ◽  
Middle Eastern Population

scholarly journals REPRODUCTIBILITY OF A METABOLITE RISK SCORE TO PREDICT CORONARY HEART DISEASE IN A MIDDLE EASTERN POPULATION

2021 ◽  
Vol 77 (18) ◽  
pp. 107
Author(s):  
Ayman El-Menyar ◽  
Ehsan Ullah ◽  
Khalid Kunji ◽  
Reem Elsousy ◽  
Amna Al-Nesf ◽  
...  
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Risk Score ◽  
Middle Eastern ◽  
Eastern Population ◽  
Middle Eastern Population

scholarly journals Validation of the Framingham hypertension risk score in a middle eastern population: Tehran lipid and glucose study (TLGS)

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Fatemeh Koohi ◽  
Ewout W. Steyerberg ◽  
Leila Cheraghi ◽  
Alireza Abdshah ◽  
Fereidoun Azizi ◽  
...  
Keyword(s):  
Simple Model ◽  
Risk Score ◽  
Screening Tool ◽  
Middle Eastern ◽  
Predictive Ability ◽  
Eastern Population ◽  
Hypertension Risk ◽  
Graphical Comparison ◽  
Middle Eastern Population

Abstract Background The Framingham hypertension risk score is a well-known and simple model for predicting hypertension in adults. In the current study, we aimed to assess the predictive ability of this model in a Middle Eastern population. Methods We studied 5423 participants, aged 20–69 years, without hypertension, who participated in two consecutive examination cycles of the Tehran Lipid and Glucose Study (TLGS). We assessed discrimination based on Harrell’s concordance statistic (c-index) and calibration (graphical comparison of predicted vs. observed). We evaluated the original, recalibrated (for intercept and slope), and revised (for beta coefficients) models. Results Over the 3-year follow-up period, 319 participants developed hypertension. The Framingham hypertension risk score performed well in discriminating between individuals who developed hypertension and those who did not (c-index = 0.81, 95% CI: 0.79–0.83). Initially, there was a systematic underestimation of the original risk score (events predicted), which was readily corrected by a simple model revision. Conclusions The revised Framingham hypertension risk score can be used as a screening tool in public health and clinical practice to facilitate the targeting of preventive interventions in high-risk Middle Eastern people.

Sign in / Sign up

Export Citation Format

Share Document