scholarly journals Calmodulin 4 is dispensable for epidermal barrier formation and wound healing in mice

2014 ◽  
Vol 24 (1) ◽  
pp. 55-57 ◽  
Author(s):  
Juliane C. Lessard ◽  
Alexandr Kalinin ◽  
Paul W. Bible ◽  
Maria I. Morasso
Keyword(s):  
Wound Healing ◽  
Epidermal Barrier ◽  
Barrier Formation

scholarly journals Improved epidermal barrier formation in human skin models by chitosan modulated dermal matrices

PLoS ONE ◽  
2017 ◽  
Vol 12 (3) ◽  
pp. e0174478 ◽  
Author(s):  
Arnout Mieremet ◽  
Marion Rietveld ◽  
Samira Absalah ◽  
Jeroen van Smeden ◽  
Joke A. Bouwstra ◽  
...  
Keyword(s):  
Human Skin ◽  
Epidermal Barrier ◽  
Barrier Formation ◽  
Dermal Matrices ◽  
Human Skin Models

scholarly journals 225 Desmoglein 1 deficiency in knockout mice impairs epidermal barrier formation and results in a psoriasis-like gene signature in E18.5 embryos

2020 ◽  
Vol 140 (7) ◽  
pp. S26
Author(s):  
Q.R. Roth-Carter ◽  
L. Godsel ◽  
J.L. Koetsier ◽  
J.A. Broussard ◽  
H.E. Burks ◽  
...  
Keyword(s):  
Knockout Mice ◽  
Gene Signature ◽  
Epidermal Barrier ◽  
Barrier Formation

scholarly journals Epidermal mammalian target of rapamycin complex 2 controls lipid synthesis and filaggrin processing in epidermal barrier formation

2020 ◽  
Vol 145 (1) ◽  
pp. 283-300.e8 ◽  
Author(s):  
Xiaolei Ding ◽  
Sebastian Willenborg ◽  
Wilhelm Bloch ◽  
Sara A. Wickström ◽  
Prerana Wagle ◽  
...  
Keyword(s):  
Mammalian Target Of Rapamycin ◽  
Lipid Synthesis ◽  
Target Of Rapamycin ◽  
Epidermal Barrier ◽  
Barrier Formation

An ancient control of epithelial barrier formation and wound healing

BioEssays ◽  
2005 ◽  
Vol 27 (10) ◽  
pp. 987-990 ◽  
Author(s):  
Bernard Moussian ◽  
Anne E. Uv
Keyword(s):  
Wound Healing ◽  
Epithelial Barrier ◽  
Barrier Formation

scholarly journals Akt-dependent Pp2a activity is required for epidermal barrier formation during late embryonic development

Development ◽  
2009 ◽  
Vol 136 (20) ◽  
pp. 3423-3431 ◽  
Author(s):  
R. F. L. O'Shaughnessy ◽  
J. C. Welti ◽  
K. Sully ◽  
C. Byrne
Keyword(s):  
Embryonic Development ◽  
Epidermal Barrier ◽  
Pp2a Activity ◽  
Barrier Formation

scholarly journals Experimental Models for the Study of Hereditary Cornification Defects

Biomedicines ◽  
2021 ◽  
Vol 9 (3) ◽  
pp. 238
Author(s):  
Dragan Copic ◽  
Maria Laggner ◽  
Polina Kalinina ◽  
Katharina Klas ◽  
Erwin Tschachler ◽  
...  
Keyword(s):  
Clinical Practice ◽  
Broad Spectrum ◽  
Experimental Models ◽  
Structural Proteins ◽  
Epidermal Barrier ◽  
Barrier Formation ◽  
Different Types ◽  
Keratinization Disorders

Ichthyoses comprise a broad spectrum of keratinization disorders due to hereditary defects of cornification. Until now, mutations in more than 50 genes, mostly coding for structural proteins involved in epidermal barrier formation, have been identified as causes for different types of these keratinization disorders. However, due to the high heterogeneity and difficulties in the establishment of valid experimental models, research in this field remains challenging and translation of novel findings to clinical practice is difficult. In this review, we provide an overview of existing models to study hereditary cornification defects with focus on ichthyoses and palmoplantar keratodermas.

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