The balance between pro- and anti-inflammatory cytokines is crucial in human allergic contact dermatitis pathogenesis: the role of IL-1 family members

2013 ◽  
Vol 22 (12) ◽  
pp. 813-819 ◽  
Author(s):  
Martina Mattii ◽  
Fabio Ayala ◽  
Nicola Balato ◽  
Raffaele Filotico ◽  
Serena Lembo ◽  
...  
Keyword(s):  
Contact Dermatitis ◽  
Allergic Contact Dermatitis ◽  
Inflammatory Cytokines ◽  
Family Members ◽  
Anti Inflammatory ◽  
Allergic Contact

Red Grape Polyphenol Oral Administration improves Immune Response in Women Affected by Nickel-Mediated Allergic Contact Dermatitis

2020 ◽  
Vol 20 ◽  
Author(s):  
Thea Magrone ◽  
Emilio Jirillo ◽  
Manrico Magrone ◽  
Matteo Antonio Russo ◽  
Paolo Romita ◽  
...  
Keyword(s):  
Contact Dermatitis ◽  
Oral Administration ◽  
Allergic Contact Dermatitis ◽  
Laboratory Data ◽  
Anti Oxidant ◽  
Anti Inflammatory ◽  
Red Grape ◽  
Allergic Contact ◽  
Drop Outs

Background: Our previous findings demonstrated that in vitro supplementation of polyphenols, extracted from seeds of red grape (Nero di Troia cultivar), to peripheral lymphomonocytes from patients affected by allergic contact dermatitis (ACD) to nickel (Ni) could reduce release of pro-inflammatory cytokines and nitric oxide (NO), while increasing levels of interleukin (IL)-10, an anti-inflammatory cytokine. Objective: To assess whether an intervention with oral administration of polyphenols leads to a reduction of peripheral biomarkers in ACD patients. Method: At T0, 25 patients affected by ACD to Ni were orally administered with 300 mg polyphenols prodie extracted from seeds of red grape (Nero di Troia cultivar) (NATUR-OX®) for 3 months (T1). Other 25 patients affected by ACD to Ni received placebo only for the same period of time. Serum biomarkers were analyzed at T0 and T1. In both groups seven drop outs were recorded. Result: At T1 in comparison to T0, in treated patients, values of IFN-γ, IL-4, IL-17, PTX3 and NO decreased, while IL-10 levels increased when compared with T0 values. Conversely, in placebo-treated patients no modifications of biomarkers were evaluated at T1. Conclusion: Present laboratory data rely on the anti-oxidant, anti-inflammatory and anti-allergic properties of polyphenols.

scholarly journals Anti-inflammatory Properties of Cannabidiol, a Nonpsychotropic Cannabinoid, in Experimental Allergic Contact Dermatitis

2018 ◽  
Vol 365 (3) ◽  
pp. 652-663 ◽  
Author(s):  
Stefania Petrosino ◽  
Roberta Verde ◽  
Massimo Vaia ◽  
Marco Allarà ◽  
Teresa Iuvone ◽  
...  
Keyword(s):  
Contact Dermatitis ◽  
Allergic Contact Dermatitis ◽  
Anti Inflammatory ◽  
Allergic Contact ◽  
Experimental Allergic

The Role of Cleaning Products in Epidemic Allergic Contact Dermatitis to Methylchloroisothiazolinone/Methylisothiazolinone

Dermatitis ◽  
2018 ◽  
Vol 29 (2) ◽  
pp. 77-80 ◽  
Author(s):  
Gabriel Marrero-Alemán ◽  
Pedro Saavedra Santana ◽  
Federica Liuti ◽  
Noelia Hernández ◽  
Esmeralda López-Jiménez ◽  
...  
Keyword(s):  
Contact Dermatitis ◽  
Allergic Contact Dermatitis ◽  
Cleaning Products ◽  
Allergic Contact

Possible role of regional variation in allergic contact dermatitis: case report

2018 ◽  
Vol 78 (3) ◽  
pp. 228-229 ◽  
Author(s):  
Austin Jiang ◽  
Joel C. Harrison ◽  
Paul D. Siegel ◽  
Howard Maibach
Keyword(s):  
Case Report ◽  
Contact Dermatitis ◽  
Allergic Contact Dermatitis ◽  
Regional Variation ◽  
Allergic Contact

The role of nitric oxide in allergic contact dermatitis

2001 ◽  
Vol 293 (4) ◽  
pp. 214-217 ◽  
Author(s):  
Sakire Sahin ◽  
Meltem Önder ◽  
Banu Sancak ◽  
Neslihan Bukan ◽  
M. Ali Gürer
Keyword(s):  
Nitric Oxide ◽  
Contact Dermatitis ◽  
Allergic Contact Dermatitis ◽  
Allergic Contact

New insights into the role of T cells in atopic dermatitis and allergic contact dermatitis

2001 ◽  
Vol 22 (10) ◽  
pp. 530-532 ◽  
Author(s):  
Axel Trautmann ◽  
Mübeccel Akdis ◽  
Eva-B Bröcker ◽  
Kurt Blaser ◽  
Cezmi A Akdis
Keyword(s):  
T Cells ◽  
Atopic Dermatitis ◽  
Contact Dermatitis ◽  
Allergic Contact Dermatitis ◽  
Allergic Contact
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