The use of equine chondrogenic‐induced mesenchymal stem cells as a treatment for osteoarthritis: A randomised, double‐blinded, placebo‐controlled proof‐of‐concept study

S. Y. Broeckx; A. M. Martens; A. L. Bertone; L. Van Brantegem; L. Duchateau; L. Van Hecke; M. Dumoulin; M. Oosterlinck; K. Chiers; H. Hussein; F. Pille; J. H. Spaas

doi:10.1111/evj.13089

The use of equine chondrogenic‐induced mesenchymal stem cells as a treatment for osteoarthritis: A randomised, double‐blinded, placebo‐controlled proof‐of‐concept study

Equine Veterinary Journal ◽

10.1111/evj.13089 ◽

2019 ◽

Vol 51 (6) ◽

pp. 787-794 ◽

Cited By ~ 8

Author(s):

S. Y. Broeckx ◽

A. M. Martens ◽

A. L. Bertone ◽

L. Van Brantegem ◽

L. Duchateau ◽

...

Keyword(s):

Stem Cells ◽

Mesenchymal Stem Cells ◽

Proof Of Concept ◽

Concept Study ◽

Double Blinded

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A proof-of-concept study assessing the potential of allogeneic chondrogenic induced mesenchymal stem cells as a treatment for osteoarthritis in the horse

Equine Veterinary Journal ◽

10.1111/evj.23_13008 ◽

2018 ◽

Vol 50 ◽

pp. 15-16

Keyword(s):

Stem Cells ◽

Mesenchymal Stem Cells ◽

Proof Of Concept ◽

Concept Study

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Therapeutic Application of Autologous ADMSCS (Adipose Derived Mesenchymal Stem Cells) and Islet like Cell Aggregates (ICAS) Derived from them in Type 1 and 2 Diabetes Mellitus - A Proof of Concept Study

Stem Cells Research Development & Therapy ◽

10.24966/srdt-2060/100008 ◽

2016 ◽

Vol 3 (1) ◽

pp. 1-6

Author(s):

Anant Marathe ◽

Keyword(s):

Diabetes Mellitus ◽

Stem Cells ◽

Mesenchymal Stem Cells ◽

Cell Aggregates ◽

Proof Of Concept ◽

Therapeutic Application ◽

Concept Study

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A novel therapeutic combination of mesenchymal stem cells and stigmasterol to attenuate osteoarthritis in rodent model system— a proof of concept study

Stem Cell Investigation ◽

10.21037/sci-2020-048 ◽

2021 ◽

Vol 8 ◽

pp. 5-5

Author(s):

Samuel Joshua Pragasam Sampath ◽

Nagasuryaprasad Kotikalapudi ◽

Vijayalakshmi Venkatesan

Keyword(s):

Stem Cells ◽

Mesenchymal Stem Cells ◽

Model System ◽

Rodent Model ◽

Proof Of Concept ◽

Concept Study ◽

System A ◽

Novel Therapeutic

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Autologous mesenchymal stem cells for the treatment of secondary progressive multiple sclerosis: an open-label phase 2a proof-of-concept study

The Lancet Neurology ◽

10.1016/s1474-4422(11)70305-2 ◽

2012 ◽

Vol 11 (2) ◽

pp. 150-156 ◽

Cited By ~ 356

Author(s):

Peter Connick ◽

Madhan Kolappan ◽

Charles Crawley ◽

Daniel J Webber ◽

Rickie Patani ◽

...

Keyword(s):

Multiple Sclerosis ◽

Stem Cells ◽

Mesenchymal Stem Cells ◽

Progressive Multiple Sclerosis ◽

Proof Of Concept ◽

Open Label ◽

Concept Study ◽

Secondary Progressive ◽

Open Label Phase ◽

Autologous Mesenchymal Stem Cells

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AUTOLOGOUS MESENCHYMAL STEM CELLS FOR THE TREATMENT OF SECONDARY PROGRESSIVE MULTIPLE SCLEROSIS: AN OPEN–LABEL PHASE 2A PROOF–OF–CONCEPT STUDY

Journal of Neurology Neurosurgery & Psychiatry ◽

10.1136/jnnp-2013-306573.25 ◽

2013 ◽

Vol 84 (11) ◽

pp. e2.140-e2

Author(s):

Peter Connick ◽

Siddharthan Chandran

Keyword(s):

Multiple Sclerosis ◽

Stem Cells ◽

Mesenchymal Stem Cells ◽

Progressive Multiple Sclerosis ◽

Proof Of Concept ◽

Open Label ◽

Concept Study ◽

Secondary Progressive ◽

Open Label Phase ◽

Autologous Mesenchymal Stem Cells

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Combined ascorbic acid and T3 produce better healing compared to bone marrow mesenchymal stem cells in an Achilles tendon injury rat model: a proof of concept study

Journal of Orthopaedic Surgery and Research ◽

10.1186/s13018-019-1098-9 ◽

2019 ◽

Vol 14 (1) ◽

Cited By ~ 7

Author(s):

Francesco Oliva ◽

Nicola Maffulli ◽

Clarissa Gissi ◽

Francesca Veronesi ◽

Lucia Calciano ◽

...

Keyword(s):

Stem Cells ◽

Bone Marrow ◽

Ascorbic Acid ◽

Mesenchymal Stem Cells ◽

Achilles Tendon ◽

Rat Model ◽

Tendon Injury ◽

Proof Of Concept ◽

Concept Study ◽

Marrow Mesenchymal Stem Cells

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Intramyocardial Transplantation and Tracking of Human Mesenchymal Stem Cells in a Novel Intra-Uterine Pre-Immune Fetal Sheep Myocardial Infarction Model: A Proof of Concept Study

PLoS ONE ◽

10.1371/journal.pone.0057759 ◽

2013 ◽

Vol 8 (3) ◽

pp. e57759 ◽

Cited By ~ 12

Author(s):

Maximilian Y. Emmert ◽

Benedikt Weber ◽

Petra Wolint ◽

Thomas Frauenfelder ◽

Steffen M. Zeisberger ◽

...

Keyword(s):

Myocardial Infarction ◽

Stem Cells ◽

Mesenchymal Stem Cells ◽

Human Mesenchymal Stem Cells ◽

Proof Of Concept ◽

Fetal Sheep ◽

Concept Study

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Treatment of osteonecrosis of the femoral head by core decompression and implantation of fully functional ex vivo-expanded bone marrow-derived mesenchymal stem cells: a proof-of-concept study

Stem Cells and Cloning Advances and Applications ◽

10.2147/sccaa.s181883 ◽

2019 ◽

Vol Volume 12 ◽

pp. 11-16 ◽

Cited By ~ 1

Author(s):

Rodrigo Mardones ◽

Daniel Camacho ◽

Francisco Monsalvo ◽

Nicolás Zülch ◽

Claudio Jofre ◽

...

Keyword(s):

Stem Cells ◽

Bone Marrow ◽

Mesenchymal Stem Cells ◽

Femoral Head ◽

Ex Vivo ◽

Core Decompression ◽

Proof Of Concept ◽

Concept Study

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The arrhythmogenic potential of nerve agents and a cardiac safety profile of antidotes - A proof-of-concept study using human induced pluripotent stem cells derived cardiomyocytes (hiPSC-CM)

Toxicology Letters ◽

10.1016/j.toxlet.2019.03.003 ◽

2019 ◽

Vol 308 ◽

pp. 1-6 ◽

Cited By ~ 4

Author(s):

Niko Amend ◽

Horst Thiermann ◽

Franz Worek ◽

Timo Wille

Keyword(s):

Stem Cells ◽

Induced Pluripotent Stem Cells ◽

Pluripotent Stem Cells ◽

Safety Profile ◽

Nerve Agents ◽

Proof Of Concept ◽

Cardiac Safety ◽

Concept Study ◽

Arrhythmogenic Potential ◽

Induced Pluripotent

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Assessment of the effect of intraarticular injection of autologous adipose-derived mesenchymal stem cells in osteoarthritic dogs using a double blinded force platform analysis

BMC Veterinary Research ◽

10.1186/1746-6148-10-143 ◽

2014 ◽

Vol 10 (1) ◽

pp. 143 ◽

Cited By ~ 51

Author(s):

Jose M Vilar ◽

Miguel Batista ◽

Manuel Morales ◽

Angelo Santana ◽

Belén Cuervo ◽

...

Keyword(s):

Stem Cells ◽

Mesenchymal Stem Cells ◽

Force Platform ◽

Intraarticular Injection ◽

Double Blinded

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