The use of porcine urinary bladder matrix ( UBM ) to repair a perforated corneal ulcer with iris prolapse in a horse

2017 ◽  
Vol 31 (4) ◽  
pp. 172-178 ◽  
Author(s):  
A. M. Davis ◽  
C. M. Riggs ◽  
D. W. Y. Chow
Keyword(s):  
Urinary Bladder ◽  
Corneal Ulcer ◽  
Urinary Bladder Matrix ◽  
Iris Prolapse

Effect of Acellular Bovine Pericardium and Urinary Bladder Submucosa Matrixes in Reconstruction of Ventro-Lateral Hernias in Bucks; Molecular Evaluation

2019 ◽  
Vol 43 (1) ◽  
pp. 67-74
Author(s):  
Areeg K. M. Al-ebadi
Keyword(s):  
Vascular Endothelial Growth Factor ◽  
Growth Factor ◽  
Treatment Group ◽  
Urinary Bladder ◽  
Bovine Pericardium ◽  
Vascular Endothelial ◽  
Fibroblast Growth ◽  
Urinary Bladder Matrix ◽  
Endothelial Growth Factor ◽  
Molecular Evaluation

The present study aimed to estimate the efficiency of both a cellular bovine pericardium and bovine urinary bladder matrix sheets in the reconstruction of large ventro-lateral hernias in Iraqi bucks by using of molecular evaluation depending on real time-polymerase chain reaction technique to investigate the level of basic-fibroblast growth factor  and vascular endothelial growth factor  genes during the healing process and reconstruction of the abdominal defects. Under sedation and local anesthesia, (6cm X 8cm size) of ventro-lateral hernias were induced in 24 of Iraqi bucks. The animals were divided randomly into two main equal groups. In bovine pericardium-treatment group, the hernias were treated with onlay implantation of bovine pericardium. While, the hernias in UBM-treatment group were treated with onlay implantation of urinary bladder matrix, 30 days post-inducing of hernias. The molecular evaluation along the period of following-up recorded a significant up-regulation of the level of basic-fibroblast growth factor gene specific for presence of fibroblasts, myofibroblasts and collagen deposition in urinary bladder matrix -treatment group in comparison to bovine pericardium -treatment group with significant difference even at the end of the study. While, a significant up regulation of the levels of angiogenesis classic gene vascular endothelial growth factor  were recorded in the bucks of bovine pericardium -treatment group compared to urinary bladder matrix -treatment group. In conclusion; molecular detection of the level of growth factors in target tissue can be used as an important criterion.

scholarly journals Comparison ofin vivoremodeling of urinary bladder matrix and acellular dermal matrix in an ovine model

2018 ◽  
Vol 13 (7) ◽  
pp. 759-773 ◽  
Author(s):  
D Adam Young ◽  
Kirk C McGilvray ◽  
Nicole Ehrhart ◽  
Thomas W Gilbert
Keyword(s):  
Urinary Bladder ◽  
Acellular Dermal Matrix ◽  
Ovine Model ◽  
Dermal Matrix ◽  
Urinary Bladder Matrix ◽  
Acellular Dermal

Urinary Bladder Matrix Protects Host in a Murine Model of Bacterial-Induced Lung Infection

2019 ◽  
Vol 25 (3-4) ◽  
pp. 257-270 ◽  
Author(s):  
Chen Chen ◽  
Xiaoping Zhang ◽  
Qiao Lin ◽  
Nathaniel T. Remlinger ◽  
Thomas W. Gilbert ◽  
...  
Keyword(s):  
Urinary Bladder ◽  
Murine Model ◽  
Lung Infection ◽  
Urinary Bladder Matrix

Evaluation of the bioactivity about anti-sca-1/basic fibroblast growth factor-urinary bladder matrix scaffold for pelvic reconstruction

2018 ◽  
Vol 33 (6) ◽  
pp. 808-818 ◽  
Author(s):  
Jiankui Li ◽  
Xi Chen ◽  
Kaijian Ling ◽  
Zhiqing Liang ◽  
Huicheng Xu
Keyword(s):  
Growth Factor ◽  
Urinary Bladder ◽  
Fibroblast Growth Factor ◽  
Basic Fibroblast Growth Factor ◽  
Pelvic Organ ◽  
Fibroblast Growth ◽  
Pelvic Reconstruction ◽  
Urinary Bladder Matrix

Introduction and hypothesis: Pelvic support structure injury is the major cause of pelvic organ prolapse. At present, polypropylene-based filler material has been suggested as a common method to treat pelvic organ prolapse. However, it cannot functionally rehabilitate the pelvic support structure. In addition to its poor long-term efficiency, the urinary bladder matrix was the most suitable biological scaffold material for pelvic floor repair. Here, we hypothesize that anti-sca-1 monoclonal antibody and basic fibroblast growth factor were cross-linked to urinary bladder matrix to construct a two-factor bioscaffold for pelvic reconstruction. Methods Through a bispecific cross-linking reagent, sulfosuccinimidyl 4-[N-maleimidomethyl] cyclohexane-1-carboxylate (sulfo-smcc) immobilized anti-sca-1 and basic fibroblast growth factor to urinary bladder matrix. Then scanning electron microscope and plate reader were used to detect whether the anti-sca-1/basic fibroblast growth factor-urinary bladder matrix scaffold was built successfully. After that, the capacity of enriching sca-1 positive cells was measured both in vitro and in vivo. In addition, we evaluated the differentiation capacity and biocompatibility of the scaffold. Finally, western blotting was used to detect the level of fibulin-5 protein. Results The scanning electron microscope and plate reader revealed that the double-factor biological scaffold was built successfully. The scaffold could significantly enrich a large number of sca-1 positive cells both in vitro and in vivo, and obviously accelerate cells and differentiate functional tissue with good biocompatibility. Moreover, the western blotting showed that the scaffold could improve the expression of fibulin-5 protein. Conclusion The anti-sca-1/basic fibroblast growth factor-urinary bladder matrix scaffold revealed good biological properties and might serve as an ideal scaffold for pelvic reconstruction.

scholarly journals Proteomic composition and immunomodulatory properties of urinary bladder matrix scaffolds in homeostasis and injury

2017 ◽  
Vol 29 ◽  
pp. 14-23 ◽  
Author(s):  
Kaitlyn Sadtler ◽  
Sven D. Sommerfeld ◽  
Matthew T. Wolf ◽  
Xiaokun Wang ◽  
Shoumyo Majumdar ◽  
...  
Keyword(s):  
Urinary Bladder ◽  
Urinary Bladder Matrix ◽  
Immunomodulatory Properties

Transvaginal Repair of Complex Rectovaginal Fistulas Using the Porcine Urinary Bladder Matrix as an Augmenting Graft

2017 ◽  
Vol 23 (3) ◽  
pp. e25-e28
Author(s):  
Hemikaa Devakumar ◽  
Neeraja Chandrasekaran ◽  
Alexandriah Alas ◽  
Laura Martin ◽  
G. Willy Davila ◽  
...  
Keyword(s):  
Urinary Bladder ◽  
Transvaginal Repair ◽  
Urinary Bladder Matrix ◽  
Rectovaginal Fistulas

Effects of topical applications of porcine acellular urinary bladder matrix and Centella asiatica extract on oral wound healing in a rat model

2018 ◽  
Vol 23 (5) ◽  
pp. 2083-2095 ◽  
Author(s):  
Fabio Camacho-Alonso ◽  
M. R. Torralba-Ruiz ◽  
N. García-Carrillo ◽  
J. Lacal-Luján ◽  
F. Martínez-Díaz ◽  
...  
Keyword(s):  
Wound Healing ◽  
Urinary Bladder ◽  
Rat Model ◽  
Centella Asiatica ◽  
Urinary Bladder Matrix ◽  
Oral Wound Healing ◽  
Topical Applications
Sign in / Sign up

Export Citation Format

Share Document