Multilobar unilateral hypoplasia with emphasis on the posterior quadrant and severe epilepsy in children with FCD ILAE Type 1A

Epilepsia ◽  
2021 ◽  
Author(s):  
Hans Holthausen ◽  
Roland Coras ◽  
Yingying Tang ◽  
Lily Bai ◽  
Irene Wang ◽  
...  
Keyword(s):  
Posterior Quadrant ◽  
Severe Epilepsy

Role of pinnae and head movements in localizing pure tones 1The authors would like to thank Mr. Remi Humbert for implementing the experiment in Turbo Pascal and for his further assistance.

1999 ◽  
Vol 58 (3) ◽  
pp. 170-179 ◽  
Author(s):  
Barbara S. Muller ◽  
Pierre Bovet
Keyword(s):  
Sound Source ◽  
Head Movement ◽  
Movement Analysis ◽  
Head Movements ◽  
Sound Sources ◽  
Localization Accuracy ◽  
Sound Effects ◽  
Posterior Quadrant ◽  
Localization Performance ◽  
Pure Tones

Twelve blindfolded subjects localized two different pure tones, randomly played by eight sound sources in the horizontal plane. Either subjects could get information supplied by their pinnae (external ear) and their head movements or not. We found that pinnae, as well as head movements, had a marked influence on auditory localization performance with this type of sound. Effects of pinnae and head movements seemed to be additive; the absence of one or the other factor provoked the same loss of localization accuracy and even much the same error pattern. Head movement analysis showed that subjects turn their face towards the emitting sound source, except for sources exactly in the front or exactly in the rear, which are identified by turning the head to both sides. The head movement amplitude increased smoothly as the sound source moved from the anterior to the posterior quadrant.

scholarly journals Comparison of the accuracy of intraoral scans between complete-arch scan and quadrant scan

2020 ◽  
Vol 21 (1) ◽  
Author(s):  
Youn-Gyeong Moon ◽  
Kyung-Min Lee
Keyword(s):  
Third Molar ◽  
Careful Consideration ◽  
Missing Teeth ◽  
Posterior Teeth ◽  
Anterior Teeth ◽  
Posterior Quadrant ◽  
Left Posterior ◽  
The Right ◽  
Best Fit ◽  
Posterior Area

Abstract Objective To compare the accuracy of complete-arch scans and quadrant scans obtained using a direct chairside intraoral scanner. Material and methods Intraoral scans were obtained from 20 adults without missing teeth except for the third molar. Maxillary and mandibular complete-arch scans were carried out, and 4 quadrant scans for each arch were performed to obtain right posterior, right anterior, left anterior, and left posterior quadrant scans. Complete-arch scans and quadrant scans were compared with corresponding model scans using best-fit surface-based registration. Shell/shell deviations were computed for complete-arch scans and quadrant scans and compared between the complete-arch scans and each quadrant scans. In addition, shell/shell deviations were calculated also for each individual tooth in complete-arch scans to evaluate factors which influence the accuracy of intraoral scans. Results Complete-arch scans showed relatively greater errors (0.09 ~ 0.10 mm) when compared to quadrant scans (0.05 ~ 0.06 mm). The errors were greater in the maxillary scans than in the mandibular scans. The evaluation of errors for each tooth showed that the errors were greater in posterior teeth than in anterior teeth. Comparing the right and left errors, the right side posterior teeth showed a more substantial variance than the left side in the mandibular scans. Conclusion The scanning accuracy has a difference between complete-arch scanning and quadrant scanning, particularly in the posterior teeth. Careful consideration is needed to avoid scanning inaccuracy for maxillary or mandibular complete-arch, particularly in the posterior area because a complete-arch scan might have potential error than a quadrant scan.

Severe epilepsy in CNTNAP2-related Pitt-Hopkins-like syndrome successfully treated with stiripentol

Seizure ◽  
2021 ◽  
Vol 88 ◽  
pp. 143-145
Author(s):  
Elena Freri ◽  
Barbara Castellotti ◽  
Laura Canafoglia ◽  
Francesca Ragona ◽  
Roberta Solazzi ◽  
...  
Keyword(s):  
Severe Epilepsy

Progabide Treatment in Severe Epilepsy: A Double-Blind Cross-over Trial Versus Placebo

Epilepsia ◽  
1984 ◽  
Vol 25 (5) ◽  
pp. 586-593 ◽  
Author(s):  
J. M. Martínez-Lage ◽  
L. Bossi ◽  
G. Morales ◽  
E. Martinez Vila ◽  
B. Orofiamma ◽  
...  
Keyword(s):  
Double Blind ◽  
Severe Epilepsy

P138 Impact of severe epilepsy on development: recovery potential after successful early epilepsy surgery

2009 ◽  
Vol 13 ◽  
pp. S63
Author(s):  
E. Roulet-Perez ◽  
V. Davidoff ◽  
C. Mayor-Dubois ◽  
Ma. Maeder-Ingvar ◽  
M. Seeck ◽  
...  
Keyword(s):  
Epilepsy Surgery ◽  
Recovery Potential ◽  
Severe Epilepsy

Phase-amplitude coupling of interictal fast activities modulated by slow waves on scalp EEG and its correlation with seizure outcomes of disconnection surgery in children with intractable nonlesional epileptic spasms

2021 ◽  
pp. 1-9
Author(s):  
Takehiro Uda ◽  
Ichiro Kuki ◽  
Takeshi Inoue ◽  
Noritsugu Kunihiro ◽  
Hiroharu Suzuki ◽  
...  
Keyword(s):  
Therapeutic Option ◽  
Surrogate Marker ◽  
Slow Waves ◽  
Seizure Freedom ◽  
Scalp Eeg ◽  
Epileptic Spasms ◽  
Posterior Quadrant ◽  
Before And After ◽  
Phase Amplitude

OBJECTIVEEpileptic spasms (ESs) are classified as focal, generalized, or unknown onset ESs. The classification of ESs and surgery in patients without lesions apparent on MRI is challenging. Total corpus callosotomy (TCC) is a surgical option for diagnosis of the lateralization and possible treatment for ESs. This study investigated phase-amplitude coupling (PAC) of fast activity modulated by slow waves on scalp electroencephalography (EEG) to evaluate the strength of the modulation index (MI) before and after disconnection surgery in children with intractable nonlesional ESs. The authors hypothesize that a decreased MI due to surgery correlates with good seizure outcomes.METHODSThe authors studied 10 children with ESs without lesions on MRI who underwent disconnection surgeries. Scalp EEG was obtained before and after surgery. The authors collected 20 epochs of 3 minutes each during non–rapid eye movement sleep. The MI of the gamma (30–70 Hz) amplitude and delta (0.5–4 Hz) phase was obtained in each electrode. MIs for each electrode were averaged in 4 brain areas (left/right, anterior/posterior quadrants) and evaluated to determine the correlation with seizure outcomes.RESULTSThe median age at first surgery was 2.3 years (range 10 months–9.1 years). Two patients with focal onset ESs underwent anterior quadrant disconnection (AQD). TCC alone was performed in 5 patients with generalized or unknown onset ESs. Two patients achieved seizure freedom. Three patients had residual generalized onset ESs. Disconnection surgeries in addition to TCC consisted of TCC + posterior quadrant disconnection (PQD) (1 patient); TCC + AQD + PQD (1 patient); and TCC + AQD + hemispherotomy (1 patient). Seven patients became seizure free with a mean follow-up period of 28 months (range 5–54 months). After TCC, MIs in 4 quadrants were significantly lower in the 2 seizure-free patients than in the 6 patients with residual ESs (p < 0.001). After all 15 disconnection surgeries in 10 patients, MIs in the 13 target quadrants for each disconnection surgery that resulted in freedom from seizures were significantly lower than in the 26 target quadrants in patients with residual ESs (p < 0.001).CONCLUSIONSIn children with nonlesional ESs, PAC for scalp EEG before and after disconnection surgery may be a surrogate marker for control of ESs. The MI may indicate epileptogenic neuronal modulation of the interhemispheric corpus callosum and intrahemispheric subcortical network for ESs. TCC may be a therapeutic option to disconnect the interhemispheric modulation of epileptic networks.

Case Studies of Chronically Ill Children

2019 ◽  
pp. 303-336
Author(s):  
Thomas C. Gibbon ◽  
Christopher L. Schwilk ◽  
Jenifer Cline ◽  
Kimberly Matthews ◽  
Katie Sweigart ◽  
...  
Keyword(s):  
Public Schools ◽  
Case Studies ◽  
Chronic Conditions ◽  
Teacher Educators ◽  
Chronically Ill ◽  
Chronic Illnesses ◽  
Respiratory Illnesses ◽  
Number Of Children ◽  
Medical Advances ◽  
Severe Epilepsy

Medical advances have increased the number of children who have survived and are now living with chronic medical conditions (Irwin & Elam, 2011; Singer 2012). Diseases and conditions that as recently as a decade ago were considered fatal or completely debilitating are now increasingly treated as chronic conditions. Among these are several types of cancer, HIV/AIDS, respiratory illnesses, and severe epilepsy. Increasingly, students with severe chronic conditions are educated in public schools instead of home or hospital settings. The purpose of this chapter is to present case studies of real children and families that will allow educators and others a personal glimpse into the lives of children with chronic illness and their families. Suggestions for analyzing the case studies are provided that will help teachers, administrators, and teacher educators to examine the complex issues surrounding the educational needs of children with chronic illnesses.

Allopurinol in Severe Epilepsy

1988 ◽  
Vol 19 (1) ◽  
pp. 51-53 ◽  
Author(s):  
P. De Marco ◽  
P. Zagnoni
Keyword(s):  
Severe Epilepsy
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