Prolonged mechanical ventilation in patients with terminated status epilepticus and outcome: An observational cohort study

Epilepsia ◽  
2021 ◽  
Author(s):  
Sira M. Baumann ◽  
Saskia Semmlack ◽  
Anja Rybitschka ◽  
Paulina S. C. Kliem ◽  
Gian Marco De Marchis ◽  
...  
Keyword(s):  
Mechanical Ventilation ◽  
Cohort Study ◽  
Status Epilepticus ◽  
Prolonged Mechanical Ventilation ◽  
Observational Cohort Study ◽  
Observational Cohort

Peripheral muscular ultrasound as outcome assessment tool in critically ill patients on mechanical ventilation: An observational cohort study

2021 ◽  
Author(s):  
Diogo Oliveira Toledo ◽  
Branca Jardini de Freitas ◽  
Rogério Dib ◽  
Flavia Julie do Amaral Pfeilsticker ◽  
Dyaiane Marques dos Santos ◽  
...  
Keyword(s):  
Mechanical Ventilation ◽  
Cohort Study ◽  
Outcome Assessment ◽  
Critically Ill ◽  
Critically Ill Patients ◽  
Assessment Tool ◽  
Observational Cohort Study ◽  
Observational Cohort

scholarly journals Obesity and smoking as risk factors for invasive mechanical ventilation in COVID-19: A retrospective, observational cohort study

PLoS ONE ◽  
2020 ◽  
Vol 15 (12) ◽  
pp. e0238552
Author(s):  
Ana C. Monteiro ◽  
Rajat Suri ◽  
Iheanacho O. Emeruwa ◽  
Robert J. Stretch ◽  
Roxana Y. Cortes-Lopez ◽  
...  
Keyword(s):  
Mechanical Ventilation ◽  
Cohort Study ◽  
Smoking Status ◽  
Univariate Analysis ◽  
Invasive Mechanical Ventilation ◽  
Multivariable Analysis ◽  
Observational Cohort Study ◽  
Smoking History ◽  
Observational Cohort ◽  
Retrospective Observational Cohort Study

Purpose To describe the trajectory of respiratory failure in COVID-19 and explore factors associated with risk of invasive mechanical ventilation (IMV). Materials and methods A retrospective, observational cohort study of 112 inpatient adults diagnosed with COVID-19 between March 12 and April 16, 2020. Data were manually extracted from electronic medical records. Multivariable and Univariable regression were used to evaluate association between baseline characteristics, initial serum markers and the outcome of IMV. Results Our cohort had median age of 61 (IQR 45–74) and was 66% male. In-hospital mortality was 6% (7/112). ICU mortality was 12.8% (6/47), and 18% (5/28) for those requiring IMV. Obesity (OR 5.82, CI 1.74–19.48), former (OR 8.06, CI 1.51–43.06) and current smoking status (OR 10.33, CI 1.43–74.67) were associated with IMV after adjusting for age, sex, and high prevalence comorbidities by multivariable analysis. Initial absolute lymphocyte count (OR 0.33, CI 0.11–0.96), procalcitonin (OR 1.27, CI 1.02–1.57), IL-6 (OR 1.17, CI 1.03–1.33), ferritin (OR 1.05, CI 1.005–1.11), LDH (OR 1.57, 95% CI 1.13–2.17) and CRP (OR 1.13, CI 1.06–1.21), were associated with IMV by univariate analysis. Conclusions Obesity, smoking history, and elevated inflammatory markers were associated with increased need for IMV in patients with COVID-19.

scholarly journals Cumulative fluid balance predicts mortality and increases time on mechanical ventilation in ARDS patients: An observational cohort study

PLoS ONE ◽  
2019 ◽  
Vol 14 (10) ◽  
pp. e0224563 ◽  
Author(s):  
Niels van Mourik ◽  
Hennie A. Metske ◽  
Jorrit J. Hofstra ◽  
Jan M. Binnekade ◽  
Bart F. Geerts ◽  
...  
Keyword(s):  
Mechanical Ventilation ◽  
Cohort Study ◽  
Fluid Balance ◽  
Observational Cohort Study ◽  
Observational Cohort ◽  
Cumulative Fluid Balance

scholarly journals Characteristics and Outcomes of Mechanically Ventilated COVID-19 Patients—An Observational Cohort Study

2020 ◽  
pp. 088506662095480
Author(s):  
Martin Krause ◽  
David J. Douin ◽  
Kevin K. Kim ◽  
Ana Fernandez-Bustamante ◽  
Karsten Bartels
Keyword(s):  
United States ◽  
Mechanical Ventilation ◽  
Logistic Regression ◽  
Cohort Study ◽  
Intensive Care ◽  
The United States ◽  
Observational Cohort Study ◽  
Mechanically Ventilated ◽  
Independent Variables ◽  
Observational Cohort

Background: The United States currently has more confirmed cases of COVID-19 than any other country in the world. Given the variability in COVID-19 testing and prevention capability, identifying factors associated with mortality in patients requiring mechanical ventilation is critical. This study aimed to identify which demographics, comorbidities, markers of disease progression, and interventions are associated with 30-day mortality in COVID-19 patients requiring mechanical ventilation. Methods: Adult patients with a confirmed diagnosis of COVID-19 admitted to one of the health system’s intensive care units and requiring mechanical ventilation between March 9, 2020 and April 1, 2020, were included in this observational cohort study. We used Chi-Square and Mann-Whitney U tests to compare patient characteristics between deceased and living patients and multiple logistic regression to assess the association between independent variables and the likelihood of 30-day mortality. Results: We included 85 patients, of which 20 died (23.5%) within 30 days of the first hospital admission. In the univariate analysis, deceased patients were more likely ≥60 years of age (p < 0.001), non-Hispanic (p = 0.026), and diagnosed with a solid malignant tumor (p = 0.003). Insurance status also differed between survivors and non-survivors (p = 0.019). Age ≥60 and malignancy had a 9.5-fold (95% confidence interval 1.4-62.3, p = 0.020) and 5.8-fold higher odds ratio (95% confidence interval 1.2-28.4, p = 0.032) for 30-day mortality after adjusted analysis using multivariable logistic regression, while other independent variables were no longer significant. Conclusions: In our observational cohort study of 85 mechanically ventilated COVID-19 patients, age, and a diagnosis of a solid malignant tumor were associated with 30-day mortality. Our findings validate concerns for the survival of elderly and cancer patients in the face of the COVID-19 pandemic in the United States, where testing capabilities and preventative measures have been inconsistent. Preventative efforts geared to patients at risk for intensive care unit mortality from COVID-19 should be explored.

High prevalence of nonconvulsive and subtle status epilepticus in an ICU of a tertiary care center: A three-year observational cohort study

2011 ◽  
Vol 96 (1-2) ◽  
pp. 140-150 ◽  
Author(s):  
Diana Rudin ◽  
Leticia Grize ◽  
Christian Schindler ◽  
Stephan Marsch ◽  
Stephan Rüegg ◽  
...  
Keyword(s):  
Cohort Study ◽  
Status Epilepticus ◽  
Care Center ◽  
Tertiary Care ◽  
Observational Cohort Study ◽  
Tertiary Care Center ◽  
High Prevalence ◽  
Observational Cohort
Sign in / Sign up

Export Citation Format

Share Document