Imaging biomarkers of behavioral impairments: A pilot micro-positron emission tomographic study in a rat electrical post-status epilepticus model

Epilepsia ◽  
2018 ◽  
Vol 59 (12) ◽  
pp. 2194-2205 ◽  
Author(s):  
R. Maarten van Dijk ◽  
Valentina Di Liberto ◽  
Matthias Brendel ◽  
Ann Marie Waldron ◽  
Christina Möller ◽  
...  
Keyword(s):  
Status Epilepticus ◽  
Imaging Biomarkers ◽  
Positron Emission Tomographic ◽  
Positron Emission ◽  
Behavioral Impairments

Asymmetric somatosensory activation with right- vs left-hand stimulation: a positron emission tomographic study

1989 ◽  
Vol 483 (2) ◽  
pp. 355-360 ◽  
Author(s):  
Fumihito Yoshii ◽  
Myron D. Ginsberg ◽  
Roger E. Kelley ◽  
Jen Y. Chang ◽  
Warren W. Barker ◽  
...  
Keyword(s):  
Positron Emission Tomographic ◽  
Left Hand ◽  
Positron Emission

Diffuse FDG Uptake in the Lungs in Aspiration Pneumonia on Positron Emission Tomographic Imaging

2004 ◽  
Vol 29 (9) ◽  
pp. 567-568 ◽  
Author(s):  
Jian Q. Yu ◽  
Rakesh Kumar ◽  
Yan Xiu ◽  
Abass Alavi ◽  
Hongming Zhuang
Keyword(s):  
Aspiration Pneumonia ◽  
Tomographic Imaging ◽  
Positron Emission Tomographic ◽  
Fdg Uptake ◽  
Positron Emission

scholarly journals News about the Role of Fluid and Imaging Biomarkers in Neurodegenerative Diseases

Biomedicines ◽  
2021 ◽  
Vol 9 (3) ◽  
pp. 252
Author(s):  
Jacopo Meldolesi
Keyword(s):  
Neurodegenerative Diseases ◽  
Imaging Techniques ◽  
Imaging Biomarkers ◽  
Positron Emission ◽  
Specific Proteins ◽  
Great Relevance ◽  
The Brain ◽  
Positive Point

Biomarkers are molecules that are variable in their origin, nature, and mechanism of action; they are of great relevance in biology and also in medicine because of their specific connection with a single or several diseases. Biomarkers are of two types, which in some cases are operative with each other. Fluid biomarkers, started around 2000, are generated in fluid from specific proteins/peptides and miRNAs accumulated within two extracellular fluids, either the central spinal fluid or blood plasma. The switch of these proteins/peptides and miRNAs, from free to segregated within extracellular vesicles, has induced certain advantages including higher levels within fluids and lower operative expenses. Imaging biomarkers, started around 2004, are identified in vivo upon their binding by radiolabeled molecules subsequently revealed in the brain by positron emission tomography and/or other imaging techniques. A positive point for the latter approach is the quantitation of results, but expenses are much higher. At present, both types of biomarker are being extensively employed to study Alzheimer’s and other neurodegenerative diseases, investigated from the presymptomatic to mature stages. In conclusion, biomarkers have revolutionized scientific and medical research and practice. Diagnosis, which is often inadequate when based on medical criteria only, has been recently improved by the multiplicity and specificity of biomarkers. Analogous results have been obtained for prognosis. In contrast, improvement of therapy has been limited or fully absent, especially for Alzheimer’s in which progress has been inadequate. An urgent need at hand is therefore the progress of a new drug trial design together with patient management in clinical practice.

Distinct Imaging Modalities in Head and Neck Cancer: Benefits and Drawbacks

2020 ◽  
Vol 11 (SPL4) ◽  
pp. 2777-2784
Author(s):  
Dana Merin ◽  
Roshni P R
Keyword(s):  
Head And Neck Cancer ◽  
Head And Neck ◽  
Neck Cancer ◽  
Imaging Techniques ◽  
Precise Determination ◽  
Imaging Biomarkers ◽  
Selection Strategies ◽  
Positron Emission ◽  
Before And After ◽  
Oncological Imaging

This review mainly focuses on the distinct imaging techniques in for head and neck cancer (HNC), its altered techniques used in diagnosis and its applications. It also depicts the upcoming imaging methods present in the field of HNC causing areas. It explains precise determination regarding the degree and extends of neoplasm. We mainly look on to the MRI(Magnetic resonance imaging), PET(Positron emission tomography), CT (computed tomography)imaging biomarkers for the management of HNC. It plays an important role in the therapy selection strategies and also enhances the therapeutic ratio in the management of HNC. The role of imaging techniques become increasingly more crucial in the management process in locally progressed head and neck squamous cell carcinoma(HNSCC). In this structure, PET allows non-invasive assessment of a range of tumour biomarkers such as metabolism, hypoxia and proliferation. MRI techniques such as can characterize different tissues by probing into their microstructure, providing a novel methodology in oncological imaging. CT, MRI, and PET/CT are widely used to determine the presence and extent of the tumours before and after treatment. This review depicts a synopsis of the most recent imaging strategies and imaging recommendations for every one of the different strides along the clinical way of patients with head and neck malignant growth.

Sign in / Sign up

Export Citation Format

Share Document